Milan Kumar Samanta

ORCID: 0000-0002-0199-8170
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About
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Research Areas
  • CRISPR and Genetic Engineering
  • Animal Genetics and Reproduction
  • Genetically Modified Organisms Research
  • Plant responses to water stress
  • Plant Stress Responses and Tolerance
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Insect and Pesticide Research
  • Insect Resistance and Genetics
  • Plant nutrient uptake and metabolism
  • Cancer-related molecular mechanisms research
  • Plant Growth Enhancement Techniques
  • Allelopathy and phytotoxic interactions
  • Plant Molecular Biology Research
  • Phytase and its Applications
  • Pluripotent Stem Cells Research
  • RNA modifications and cancer
  • Plant Virus Research Studies
  • RNA Research and Splicing
  • Soybean genetics and cultivation
  • Plant Micronutrient Interactions and Effects
  • Rice Cultivation and Yield Improvement
  • Epigenetics and DNA Methylation
  • Tissue Engineering and Regenerative Medicine
  • Nitrogen and Sulfur Effects on Brassica
  • Chromosomal and Genetic Variations

University of Michigan–Ann Arbor
2020-2024

Indian Institute of Technology Kharagpur
2015-2017

Bose Institute
2017

Family members of sucrose non-fermenting 1-related kinase 2 (SnRK2), being plant-specific serine/threonine protein kinases, constitute the central core abscisic acid (ABA)-dependent and ABA-independent signaling pathways, are key regulators abiotic stress adaptation in plants. We report here functional characterization SAPK9 gene, one 10 SnRK2s rice, through developing gain-of-function loss-of-function phenotypes by transgenesis.The gene expression profiling revealed that abundance single...

10.1186/s12870-016-0845-x article EN cc-by BMC Plant Biology 2016-07-13

Abstract XX female and XY male therian mammals equalize X-linked gene expression through the mitotically-stable transcriptional inactivation of one two X chromosomes in somatic cells. Here, we describe an essential function homolog ancestral X-Y pair, Kdm5c - Kdm5d , Xist lncRNA, which is required for stable X-inactivation. Ablation females results a significant reduction RNA expression. encodes demethylase that enhances by converting histone H3K4me2/3 modifications into H3K4me1. Ectopic...

10.1038/s41467-022-30352-1 article EN cc-by Nature Communications 2022-05-11

Drought is one of the major limiting factors for productivity crops including rice (Oryza sativa L.). Understanding role allelic variations key regulatory genes involved in stress-tolerance essential developing an effective strategy to combat drought. The bZIP transcription play a crucial abiotic-stress adaptation plants via abscisic acid (ABA) signaling pathway. present study aimed search polymorphism OsbZIP23 gene across selected drought-tolerant and drought-sensitive genotypes,...

10.1371/journal.pone.0150763 article EN cc-by PLoS ONE 2016-03-09

Summary Conventionally, Y-linked Sry is thought to drive sex differences by triggering differential hormone production. Ancestral X-Y gene pairs, however, are hypothesized hormone-independent differences. Here, we show that the pair Kdm5c - Kdm5d regulates sex-biased expression in pluripotent mouse embryonic stem cells (ESCs). Wild-type (WT) XX female ESCs exhibit >2-fold higher of 409 genes relative WT XY male ESCs. Conversely, 126 compared Loss downregulates female-biased genes. In...

10.1101/2024.10.24.620066 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-10-27

Eukaryotic membrane lipids create hydrophobic physical barriers which control information and substance exchange between the outside inside of cells also different cellular compartments.Membrane like Phosphoinositides (PIs) exert regulatory effect on in addition to its trafficking property.Apart from that, phosphoinositide specific phospholipase C (PI-PLC), enzyme acting upon phosphoinositides, plays a significant role exerting such cell functions.PI-PLCs belong an important class enzymes...

10.16943/ptinsa/2017/49223 article EN DELETED 2017-09-01
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