B. Frąckowiak

ORCID: 0000-0002-0203-4066
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About
Contact & Profiles
Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Asymmetric Synthesis and Catalysis
  • Synthetic Organic Chemistry Methods
  • Analytical Chemistry and Chromatography
  • melanin and skin pigmentation
  • Melanoma and MAPK Pathways
  • Plant biochemistry and biosynthesis
  • Carbohydrate Chemistry and Synthesis
  • Axial and Atropisomeric Chirality Synthesis
  • Crystallography and molecular interactions
  • Chemical Synthesis and Analysis
  • Synthesis of Organic Compounds
  • Protein Kinase Regulation and GTPase Signaling
  • Chemical synthesis and alkaloids
  • Oxidative Organic Chemistry Reactions
  • Quinazolinone synthesis and applications
  • Computational Drug Discovery Methods
  • Genomics, phytochemicals, and oxidative stress
  • Free Radicals and Antioxidants
  • Structural and Chemical Analysis of Organic and Inorganic Compounds
  • Organoselenium and organotellurium chemistry
  • Insect Pheromone Research and Control
  • Cytokine Signaling Pathways and Interactions
  • Marine Sponges and Natural Products

University of Opole
2009-2023

Scripps Research Institute
2006-2013

Wrocław University of Science and Technology
1999-2006

Institute of Organic Chemistry
2002

Lactoperoxidase was previously used as a model enzyme to test the inhibitory activity of selenium analogs anti-thyroid drugs with 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) substrate. Peroxidases oxidize ABTS metastable radical ABTS•+, which is readily reduced by many antioxidants, including thiol-containing compounds, and it has been for decades measure antioxidant in biological samples. We showed that 6-n-propyl-2-thiouracil, methimazole, methimazole also rapidly. This...

10.1016/j.bioorg.2023.106891 article EN cc-by-nc-nd Bioorganic Chemistry 2023-09-27

10.1016/j.bbagen.2006.05.001 article EN Biochimica et Biophysica Acta (BBA) - General Subjects 2006-05-19

2,3-Butanediacetal derivatives were used for the stereoselective synthesis of unsymmetrically substituted cis -epoxides. The procedure was applied preparation both enantiomers disparlure and monachalure, components sex pheromones gypsy moth ( Lymantria dispar ) nun monacha using methyl (2 S ,3 R ,5 ,6 )-3-ethylsulfanylcarbonyl-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2-carboxylate as starting material.

10.3762/bjoc.16.57 article EN cc-by Beilstein Journal of Organic Chemistry 2020-04-03
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