About
Contact & Profiles
A5071474165
Research Areas
- CAR-T cell therapy research
- Virus-based gene therapy research
- Glioma Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Biomedical Ethics and Regulation
- MicroRNA in disease regulation
- Brain Metastases and Treatment
- Nanoplatforms for cancer theranostics
- Conflict of Laws and Jurisdiction
- RNA Interference and Gene Delivery
Northwestern University
2017-2021
RNA interference–based spherical nucleic acid nanoconjugates are a potentially safe and brain-penetrant approach for glioblastoma treatment.
10.1126/scitranslmed.abb3945
article
EN
Science Translational Medicine
2021-03-10
10.1016/s1470-2045(21)00245-x
article
EN
The Lancet Oncology
2021-06-29
Oncolytic virotherapy represents a potentially innovative approach for patients with malignant glioma. A major obstacle to effective therapy has been delivery of an oncolytic virus the tumor. For this first-in-human phase I clinical study, we developed novel adenovirus, CRADd-Survivin-pk7, which utilizes survivin promoter and binds heparan sulfate proteoglycans expressed on surface tumor cells. Survivin is overexpressed in gliomas also radiosensitive driving viral replication glioma but not...
10.1093/neuonc/nox168.027
article
EN
Neuro-Oncology
2017-11-01
10.1016/s0167-8140(23)08492-x
article
EN
Radiotherapy and Oncology
2023-05-01
10.1016/s0167-8140(21)00908-7
article
EN
Radiotherapy and Oncology
2020-11-01
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