A5014469662- Advanced X-ray Imaging Techniques
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced Electron Microscopy Techniques and Applications
- GaN-based semiconductor devices and materials
- Astrophysical Phenomena and Observations
- Nuclear Physics and Applications
- Laser-Plasma Interactions and Diagnostics
- Medical Imaging Techniques and Applications
- Advanced Battery Materials and Technologies
- Advancements in Battery Materials
- Crystallography and Radiation Phenomena
- ZnO doping and properties
- Advanced biosensing and bioanalysis techniques
- Electronic and Structural Properties of Oxides
- Perovskite Materials and Applications
- Geological and Geochemical Analysis
- Advanced Condensed Matter Physics
- Pediatric Urology and Nephrology Studies
- Metal and Thin Film Mechanics
- Advanced X-ray and CT Imaging
- Digital Holography and Microscopy
- Electron and X-Ray Spectroscopy Techniques
- Advanced Data Storage Technologies
- Piezoelectric Actuators and Control
- Advanced MRI Techniques and Applications
Argonne National Laboratory
2016-2025
Yunnan Normal University
2025
Yunnan University
2025
Aalto University
2025
Northwestern University
2013-2021
Oregon State University
2019
Peking University
2009-2011
Abstract Single-crystal cathode materials for lithium-ion batteries have attracted increasing interest in providing greater capacity retention than their polycrystalline counterparts. However, after being cycled at high voltages, these single-crystal exhibit severe structural instability and fade. Understanding how the surface changes determine performance degradation over cycling is crucial, but remains elusive. Here, we investigate correlation of structure, internal strain, deterioration...
RNA interference–based spherical nucleic acid nanoconjugates are a potentially safe and brain-penetrant approach for glioblastoma treatment.
Significance X-ray fluorescence microscopy provides unparalleled sensitivity for measuring the distribution of trace elements in many-micrometer-thick specimens, whereas ptychography offers a path to imaging weakly fluorescing biological ultrastructure at beyond-focusing-optic resolution. We demonstrate here first time, our knowledge, combination and frozen-hydrated specimens cryogenic temperatures, with excellent structural chemical preservation. This combined approach will have significant...
Hard X-ray fluorescence microscopy is one of the most sensitive techniques for performing trace elemental analysis biological samples such as whole cells and tissues. Conventional sample preparation methods usually involve dehydration, which removes cellular water may consequently cause structural collapse, or invasive processes embedding. Radiation-induced artifacts also become an issue, particularly spatial resolution increases beyond sub-micrometer scale. To allow imaging under hydrated...
Ptychography is an imaging method whereby a coherent beam scanned across object, and image obtained by iterative phasing of the set diffraction patterns. It able to be used extended objects at resolution limited scattering strength object detector geometry, rather than optics-imposed limit. As technical advances allow larger fields imaged, computational challenges arise for reconstructing correspondingly data volumes, yet same time there also need deliver reconstructed images immediately so...
Abstract State-of-the-art halide perovskite solar cells have bandgaps larger than 1.45 eV, which restricts their potential for realizing the Shockley-Queisser limit. Previous search low-bandgap (1.2 to 1.4 eV) perovskites has resulted in several candidates, but all are hybrid organic-inorganic compositions, raising concern regarding device stability. Here we show promise of an inorganic (1.38 CsPb 0.6 Sn 0.4 I 3 stabilized via interface functionalization. Device efficiency up 13.37% is...
Sequestration within the cytoplasm often limits efficacy of therapeutic nanoparticles that have specific subcellular targets. To allow for both cellular and nanoparticle delivery, we created epidermal growth factor receptor (EGFR)-targeted Fe3O4@TiO2 use native intracellular trafficking EGFR to improve internalization nuclear translocation in EGFR-expressing HeLa cells. While bound EGFR, these do not interfere with interaction between karyopherin-β, a protein is critical ligand-bound...
Ptychography is a coherent diffraction imaging (CDI) method for extended objects in which patterns are acquired sequentially from overlapping illumination spots. The object's complex transmission function can be reconstructed those at spatial resolution limited only by the scattering strength of object and detector geometry. Most experiments to date have positioned spots on sample using move-settle-measure sequence move settle steps take longer complete than measure step. We describe here...
X-ray microscopy can be used to image whole, unsectioned cells in their native hydrated state. It complements the higher resolution of electron for submicrometer thick specimens, and molecule-specific imaging capabilites fluorescence light microscopy. We describe here first use fast, continuous x-ray scanning frozen simultaneous sub-20 nm ptychographic transmission with high contrast, sub-100 deconvolved diffusible bound ions at concentrations, without need add specific labels. By working...
Accurate knowledge of elemental distributions within biological organisms is critical for understanding their cellular roles. The ability to couple this with overall architecture in three dimensions (3D) deepens our chemistry. Using a whole, frozen-hydrated Chlamydomonas reinhardtii cell as an example, we report the development 3D correlative microscopy through combination simultaneous cryogenic x-ray ptychography and fluorescence microscopy. By taking advantage recently developed...
Motivated by the advanced photon source upgrade, a new hard X-ray microscope called "Velociprobe" has been recently designed and built for fast ptychographic imaging with high spatial resolution. We are addressing challenges of high-resolution scanning novel hardware designs, motion controls, data acquisition strategies, including use high-bandwidth interferometric measurements. The granite, air-bearing-supported stages provides necessary long travel ranges coarse to accommodate real samples...
Today's scientific simulations require a significant reduction of data volume because extremely large amounts they produce and the limited I/O bandwidth storage space. Error-bounded lossy compression has been considered one most effective solutions to above problem. In practice, however, best-fit method often needs be customized or optimized in particular diverse characteristics different datasets various user requirements on quality performance. this paper, we address issue with novel...
The development of commercially friendly and stable catalysts for oxygen reduction reaction (ORR) is critical many energy conversion systems such as fuel cells metal–air batteries. Many Co-based perovskite oxides LaCoO3 have been discovered the active ORR catalysts, which can be good candidates to replace platinum (Pt). Although researchers tried substituting various transition metals into improve performance, influence substitution on mechanism rarely studied. In this paper, we explore...
Single-crystal Ni-rich Li[NixMnyCo1-x-y]O2 (SC-NMC) cathodes represent a promising approach to mitigate the cracking issue of conventional polycrystalline cathodes. However, many reported SC-NMC still suffer from unsatisfactory cycling stability, particularly under high charge cutoff voltage and/or elevated temperature. Herein, we report an ultraconformal and durable poly(3,4-ethylenedioxythiophene) (PEDOT) coating for using oxidative chemical vapor deposition (oCVD) technique, which...
Abstract X-ray ptychographic tomography is a nondestructive method for three dimensional (3D) imaging with nanometer-sized resolvable features. The size of the volume that can be imaged almost arbitrary, limited only by penetration depth and available scanning time. Here we present rapidly accelerates operation over given through acquiring set data via large angular reduction compensating resulting ill-posedness deeply learned priors. proposed 3D reconstruction “RAPID” relies initially on...
We fabricate heterojunctions consisting of a single n-type ZnO nanowire and p-type GaN film. The photovoltaic effect exhibits open-circuit voltages ranging from 2 to 2.7 V, maximum output power reaching 80 nW. Light-emitting diodes with UV electroluminescence based on the are demonstrated.
Synchrotron radiation light source facilities are leading the way to ultrahigh resolution X-ray imaging. High imaging is essential understanding fundamental structure and interaction of materials at smallest length scale possible. Diffraction based methods achieve nanoscale by replacing traditional objective lenses pixelated area detectors computational image reconstruction. Among these methods, ptychography quickly becoming standard for sub-30 nanometer extended samples, but expense...
Modern integrated circuits (ICs) employ a myriad of materials organized at nanoscale dimensions, and certain critical tolerances must be met for them to function. To understand departures from intended functionality, it is essential examine ICs as manufactured so adjust design rules ideally in nondestructive way that imaged structures can correlated with electrical performance. Electron microscopes do this on thin regions or exposed surfaces, but the required processing alters even destroys...
Achieving high spatial resolution is the goal of many imaging systems. Designing a high-resolution lens with diffraction-limited performance over large field view remains difficult task in system design. On other hand, creating complex speckle pattern wavelength-limited features effortless and can be implemented via simple random diffuser. With this observation inspired by concept near-field ptychography, we report new modality, termed Fourier for tackling challenges both microscopic...