A5100368679- Pharmacological Effects of Natural Compounds
- Diet, Metabolism, and Disease
- Alcohol Consumption and Health Effects
- Cardiovascular Function and Risk Factors
- International Student and Expatriate Challenges
- Chemotherapy-induced cardiotoxicity and mitigation
- Workplace Spirituality and Leadership
- Circular RNAs in diseases
- Medicinal Plants and Bioactive Compounds
- Job Satisfaction and Organizational Behavior
- Apelin-related biomedical research
- Endoplasmic Reticulum Stress and Disease
- Kruppel-like factors research
- Liver Disease Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Ginseng Biological Effects and Applications
Henan University Huaihe Hospital and Huaihe Clinical Institute
2016-2023
Salidroside, a bioactive constituent isolated from Rhodiola rosea, has been reported to have anti-inflammatory effects. However, the effects of salidroside on interleukin (IL)-1β-stimulated osteoarthritis (OA) chondrocytes remain be elucidated. Thus, this study aimed evaluate IL-1β-stimulated human OA and explore its underlying mechanisms. Our results showed that significantly inhibited production nitric oxide prostaglandin E-2, as well suppressed expression inducible synthase...
Objective To explore the effect of microRNA-22-3p (miR-22-3p) regulating expression Kruppel-like factor 6 (KLF6) on cardiomyocyte-like differentiation bone marrow mesenchymal stem cell (BMSC). Methods Rat BMSC was isolated and cultured,and third-generation divided into a control group,a 5-azacytidine(5-AZA)group,a mimics-NC miR-22-3p mimics mimics+pcDNA group,and mimics+pcDNA-KLF6 group.Real-time fluorescent quantitative PCR (qRT-PCR) carried out to determine KLF6 in cells.Immunofluorescence...