- Bone Tumor Diagnosis and Treatments
- Spinal Fractures and Fixation Techniques
- Sarcoma Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Oral and Maxillofacial Pathology
- Infectious Diseases and Tuberculosis
- Scoliosis diagnosis and treatment
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Bone fractures and treatments
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Orthopedic Infections and Treatments
- Neurofibromatosis and Schwannoma Cases
- Musculoskeletal synovial abnormalities and treatments
- Esophageal Cancer Research and Treatment
- Glioma Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Hip and Femur Fractures
- Lung Cancer Diagnosis and Treatment
- Urologic and reproductive health conditions
- Shoulder Injury and Treatment
- Management of metastatic bone disease
- Diabetes, Cardiovascular Risks, and Lipoproteins
Guangdong Academy of Medical Sciences
2019-2025
Southern Medical University
2024-2025
Guangdong Provincial People's Hospital
2005-2025
First People's Hospital of Yunnan Province
2025
Kunming University of Science and Technology
2025
Nanjing Forestry University
2025
Central South University
2015-2024
Wannan Medical College
2023-2024
Nanjing Jiangning Hospital
2024
Second Xiangya Hospital of Central South University
2015-2024
To predict the optimal cut-off values for screening and predicting metabolic syndrome(MetS) in a middle-aged elderly Chinese population using 13 obesity lipid-related indicators, to identify most suitable predictors.The data this cross-sectional investigation came from China Health Retirement Longitudinal Study (CHARLS), including 9457 people aged 45-98 years old. We examined waist circumference (WC), body mass index (BMI), waist-height ratio (WHtR), visceral adiposity (VAI), shape (ABSI),...
Abstract To investigate the screening and predicting functions of obesity- lipid-related indices for type 2 diabetes (T2D) in middle-aged elderly Chinese, as well ideal predicted cut-off value. This study's data comes from 2011 China Health Retirement Longitudinal Study (CHARLS). A cross-sectional study design was used to relationship T2D 13 indices, including body mass index (BMI), waist circumference (WC), waist–height ratio (WHtR), visceral adiposity (VAI), a shape (ABSI), roundness...
Objective Type 2 diabetes mellitus (T2DM) remains a major and widespread public health concern throughout the world. The prevalence of T2DM in elderly has risen to top list concerns. In this study, obesity- lipid-related indices were used predict middle-aged Chinese adults. Methods data came from China Health Retirement Longitudinal Study (CHARLS), including 7902 participants aged 45 years or above. study assessed association by measuring 13 indicators, body mass index (BMI), waist...
Depressive symptom is a serious mental illness often accompanied by physical and emotional problems. The prevalence of depressive in older adults has become an increasingly important public health priority. Our study used cardiometabolic indicators to predict middle-aged China.The data came from the China Health Retirement Longitudinal Study 2011 (CHARLS2011), which was cross-sectional study. analytic sample included 8,942 participants aged 45 years or above. evaluated relationship between...
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. There no nomogram model available for mortality prediction stable COPD. We intended to develop and validate a predict risk in COPD patients personalised prognostic assessment.
Abstract The purpose of the study was to determine whether changes in body mass index (BMI) and waist circumference (WC) middle-aged elderly Chinese are associated with metabolic syndrome. In this cohort investigation, 3697 people aged 45 or over were recruited from China Health Retirement Longitudinal Study (CHARLS). National Cholesterol Education Program Adult Treatment Panel III (2005) defined syndrome (MetS). With Cox regression analysis, we calculated hazard ratio (HR) 95% confidence...
Currently, clinical implications of immune system cells in chordoma remain to be elucidated.To characterize situ cell infiltrates, the Immunoscore, and investigate their correlation with clinicopathologic data spinal patients outcome.Tumor-infiltrating lymphocytes (TILs) subtypes were assessed 54 tumor specimens using immunohistochemistry for CD3, CD4, CD8, CD20, Foxp3, PD-1, PD-L1.Overall, infiltrates present all samples there was low or moderate among several TILs subsets. PD-1+ density,...
Currently, little is known about the clinical relevance of tumor-stroma ratio (TSR) in chordoma and data discussing relationship between TSR immune status are lacking.To characterize distribution spinal chordoma, investigated its correlation with clinicopathologic or immunological features patients outcome.TSR was assessed visually on hematoxylin eosin-stained sections from 54 tumor specimens by 2 independent pathologists. Multiplex immunofluorescence used to quantify expression levels...
Currently, the oncogenic mechanism of endoplasmic reticulum stress-CAF (ERS-CAF) subpopulation in chordoma remains unknown. Here, single-cell RNA sequencing, spatial transcriptomics, GeoMx Digital Spatial Profiler, data-independent acquisition proteomics, bulk RNA-seq, and multiplexed quantitative immunofluorescence are used to unveil precise molecular how ERS-CAF affected progression. Results show that hypoxic microenvironment reprograms CAFs into subtype. Mechanistically, this occurrs via...
The Capanna technique involves the use of a vascularized fibular graft inlaid in massive bone intercalary reconstruction for diaphyseal long-bone defects caused by tumor resection. Allograft-host union time varies different reports, and few studies have focused on underlying factors affecting time. purpose present study was to analyze relevant report complications technique.
Stereotactic radiosurgery is a common treatment for brain metastases and typically planned on magnetic resonance imaging (MRI). However, the MR acquisition parameters used patient selection planning stereotactic can vary within across institutions. In this work, we investigate effect of MRI slice thickness detection contoured volume metastatic lesions in brain.