A5024100049- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Peripheral Artery Disease Management
- Cardiac Structural Anomalies and Repair
- Vascular Procedures and Complications
- Cardiac pacing and defibrillation studies
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Cardiovascular Health and Disease Prevention
- Atherosclerosis and Cardiovascular Diseases
- Nutrition and Health Studies
- Systemic Lupus Erythematosus Research
- Lipoproteins and Cardiovascular Health
- Obstructive Sleep Apnea Research
- Cardiovascular Disease and Adiposity
- Inflammatory Biomarkers in Disease Prognosis
- Mast cells and histamine
Medical University of Warsaw
2016-2025
Instytut Techniczny Wojsk Lotniczych
2020
Central Clinical Hospital
2010-2019
Samodzielny Publiczny Centralny Szpital Kliniczny
2018
Abstract Background : Mast cells (MCs) are multifunctional immune that produce a number of vasoactive or thromboactive mediators. Elevated numbers human heart MCs observed in the shoulder regions coronary atherosclerotic plaques, suggesting they play role plaque rupture. Cardiac MC degranulation after myocardial ischemia has been documented animal models. highly profibrinolytic and release tryptase, their specific protease, ischemic events. Hypothesis cell activation tryptase may...
Background: Percutaneous treatment of patients with ST segment elevation myocardial infarction (STEMI) has become the standard and default mode management as recommended by European Society Cardiology guidelines for managing acute in presenting STEMI. The choice vascular access is made operator a potential impact on safety efficacy procedure outcomes. Aim: To understand influence radial approach bleeding complications angiographic success, we performed prospective, controlled randomised...
What's new?Tricuspid regurgitation only recently has been fully acknowledged as a serious condition and the target of specific treatment.Following introduction new transcatheter treatment methods, more patients with severe tricuspid (TR) could become eligible for optimization.In order to do so, there is need better characterize this demanding patient subset.Our study gives thorough characterization real-life cohort TR including clinical echocardiographic factors.Overall mortality in group...
The aim of the study was to evaluate healing process at 12 months after ABSORB™ bioresorbable vascular scaffold (BVS) implantation in patients with ST-segment elevation myocardial infarction (STEMI).There is currently no data on long-term BVS performance acute thrombotic setting. underlying altered plaque pathomorphology may impact neointima pattern, potentially making it different that observed stable coronary artery disease (CAD).We have performed an angiographic and optical coherence...
Background: optical coherence tomography (OCT) might allow identifying lesion features reportedly associated with plaque vulnerability and increased risk of clinical events. Previous studies on correlation between OCT functional significance indices reported contradictory results, yet integration complementary information from both modalities is gaining interest. The aim the study was to compare morphology using in hemodynamically relevant vs. non-relevant lesions by fractional flow reserve...
Background The pathophysiology of atherosclerotic plaque formation and its vulnerability seem to differ between genders due contrasting risk profiles sex hormones, however this process is still insufficiently understood. aim the study was compare differences sexes regarding optical coherence tomography (OCT), intravascular ultrasound (IVUS) fractional flow reserve (FFR)-derived coronary indices. Methods In single-center multimodality imaging patients with intermediate grade stenoses...
Aims: To assess for the first time in a multicentre design between-centre reproducibility of volumetric virtual histology intravascular ultrasound (VH-IVUS) measurements with semi-automated, computerassisted contour detection system mild-to-moderately diseased coronary segments.Methods and results: Analysts four European IVUS centres performed independent analyses (in total 7,188 cross-sectional analyses) obtained data to evaluate VH-IVUS 36 segments (length 20.0±0.4 mm) from patients stable...
Background: The purpose of this retrospective study was to investigate outcomes patients with severe coronary artery disease (CAD) after implementing various treatment strategies following multidisciplinary Heart Team (MHT) discussion. Methods Primary and secondary endpoints quality life during a mean (SD) follow-up 37 (14) months CAD (three-vessel [3-VD] or/and left main [LM] disease) qualified MHT discussion optimal medical (OMT) alone, OMT bypass grafting (CABG), or percutaneous...
Background: Bioresorbable vascular scaffold (BVS) implantation is a new, promising treatment method of coronary artery disease. Preliminary data in patients with stable angina are encouraging. However, the utility BVS was not sufficiently evaluated setting acute thrombotic lesions. The aim this study an optical coherence tomography (OCT) assessment procedural result everolimus-eluting ST segment elevation myocardial infarction (STEMI) and evaluation mid-term clinical outcomes. Methods: OCT...
INTRODUCTION Periprocedural myocardial injury may be associated with an increased risk of cardiovascular events. There is limited evidence on the safety and efficacy more potent P2Y12 antagonists in reduction incidence periprocedural among patients undergoing elective percutaneous coronary intervention (PCI) inadequate response to clopidogrel. OBJECTIVES The aim study was evaluate impact prasugrel PCI clopidogrel, diagnosed by point‑of‑care genotyping platelet function testing (PFT)....
Tricuspid regurgitation (TR) is a common acquired valvular heart disease (VHD). TR has progressive character and associated with impaired long-term survival in both symptomatic asymptomatic subjects. Despite this knowledge, the overall number of tricuspid valve surgeries very low worldwide many patients clear indications for intervention are left untreated. The development less invasive transcatheter techniques may offer new treatment options growing population patients. Out various...
Angiographic coronary flow parameters and resolution of ST segment changes play an important role in the evaluation reperfusion patients with acute elevation myocardial infarction (STEMI). In previous studies on relation between angiographic electrocardiographic (ECG) reperfusion, several alternative methods to assess were used. Thus, TIMI Myocardial Perfusion Grade (TMPG) different evaluate seems be interest.To relationship TMPG absolute relative after successful primary percutaneous...
Abstract The article presents methods to monitor the actual state of aircraft’s airframe, in particular, onset corrosion. greatest emphasis is put on “Corrosion Prognostic Health Management” CPHM system. Authors discuss corrosion detection using NDT as well possibilities forecasting for estimating basing data gathered by means sensors. Based results previous research and analyses, authors focus monitoring internal microclimate factors causing aspect damage tolerance operation aircraft....
INTRODUCTION Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel remains a cornerstone of pharmacotherapy after percutaneous coronary intervention (PCI). It has been demonstrated that even up to 30% patients receiving DAPT have inadequate response clopidogrel, namely, high on‑treatment platelet reactivity (HPR). The red cell distribution width (P‑RDW) ratio represents an indicator cardiovascular risk may be related HPR. OBJECTIVES aim the present study was establish whether P‑RDW...
The aim of the study was to assess vascular healing response after Absorb bioresorbable scaffold (BVS) implantation in patients with ST-segment elevation myocardial infarction (STEMI) utilising truly serial optical coherence tomography (OCT) examination at baseline, 12 and 24 months.This a single-centre, prospective, longitudinal 12- 24-month OCT evaluation 18 STEMI treated 22 BVS. pattern evaluated based upon lumen area, neointimal hyperplasia, strut coverage apposition. area decreased...
Background: Local bleedings related to vascular access site in percutaneous procedures are relatively common complications. However, no uniform definitions exist classify them. Aim: To compare minor transradial (TR) and transfemoral (TF) coronary intervention (PCI) approaches ST elevation myocardial infarction (STEMI). In addition, a new classification of TF access-related bleeding — the FEMORAL scale was proposed. Methods: OCEAN RACE is prospective, randomised, open-label, clinical trial...