A5102975883- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Galectins and Cancer Biology
- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Aortic aneurysm repair treatments
- Atherosclerosis and Cardiovascular Diseases
- Vascular Procedures and Complications
- Nutrition and Health Studies
- Advanced MRI Techniques and Applications
- Pulmonary Hypertension Research and Treatments
- MicroRNA in disease regulation
- Atrial Fibrillation Management and Outcomes
- Circular RNAs in diseases
- Systemic Lupus Erythematosus Research
- Renal and Vascular Pathologies
- Cardiac Arrhythmias and Treatments
- Kidney Stones and Urolithiasis Treatments
- GDF15 and Related Biomarkers
- Mechanical and Thermal Properties Analysis
Medical University of Warsaw
2016-2025
Erasmus MC
2017-2022
University of Amsterdam
2020
Erasmus University Rotterdam
2019
Myocardial infarction with nonobstructive coronary arteries (MINOCA) remains a puzzling clinical entity. It is characterized by evidence of myocardial (MI) normal or near-normal in angiography. Given the complex etiology including multiple possible scenarios varied pathogenetic mechanisms, profound investigation plausible biomarkers MINOCA may bring further pathophysiological insights and novel diagnostic opportunities. Cytokines have great potential are used as for many diseases. An unusual...
BACKGROUND:Prolonged QT interval is an integral part of the definition cirrhotic cardiomyopathy. The aim this study was to analyze relationship between corrected (QTc) and etiology severity liver disease in relation complications cirrhosis candidates for orthotropic transplantation (OLTx). MATERIAL AND METHODS:From 360 consecutive patients with end-stage (ESLD) consulted by a designated cardiologist, 160 underwent OLTx. QTc calculated according 3 formulas 151 ECG tracings good quality....
What's new?Tricuspid regurgitation only recently has been fully acknowledged as a serious condition and the target of specific treatment.Following introduction new transcatheter treatment methods, more patients with severe tricuspid (TR) could become eligible for optimization.In order to do so, there is need better characterize this demanding patient subset.Our study gives thorough characterization real-life cohort TR including clinical echocardiographic factors.Overall mortality in group...
Background. Galectin-3 (Gal-3) as a biomarker of fibrosis and inflammation has been implicated in the development progression heart failure (HF) may predict increased morbidity mortality society.Objectives. In this preliminary report we investigated utility novel serum marker for diagnosis acute HF (AHF).Material Methods. The study involved 14 AHF patients aged 67.0 ± 14.6 yrs. with left ventricular ejection fraction (LVEF) 29.29 10.73%, hospitalized at Intensive Coronary Care Unit, where...
Objective: Platelets are strongly associated with cardiovascular events due to their role in thrombotic processes. Reticulated platelets have higher prothrombotic potential. The aim of the study was evaluate effectiveness immature platelet fraction (IPF) predicting long-term clinical outcomes patients acute coronary syndrome (ACS). Methods: This prospective, observational enrolled ACS treated dual antiplatelet therapy comprising acetylsalicylic acid and clopidogrel or ticagrelor. primary...
Dual antiplatelet therapy (DAPT) is recommended after elective percutaneous coronary intervention (PCI) in stable artery disease (SCAD) patients; however, still one-third of patients do not obtain adequate platelet inhibition that may result increased cardiovascular risk. The aim the ONSIDE TEST study to evaluate clinical impact point-of-care genotyping- and function-based personalized dual strategies SCAD individuals undergoing PCI.Fifty were randomized one three arms: 1) genotyping, 2)...
INTRODUCTION Periprocedural myocardial injury may be associated with an increased risk of cardiovascular events. There is limited evidence on the safety and efficacy more potent P2Y12 antagonists in reduction incidence periprocedural among patients undergoing elective percutaneous coronary intervention (PCI) inadequate response to clopidogrel. OBJECTIVES The aim study was evaluate impact prasugrel PCI clopidogrel, diagnosed by point‑of‑care genotyping platelet function testing (PFT)....
Background: Local bleedings related to vascular access site in percutaneous procedures are relatively common complications. However, no uniform definitions exist classify them. Aim: To compare minor transradial (TR) and transfemoral (TF) coronary intervention (PCI) approaches ST elevation myocardial infarction (STEMI). In addition, a new classification of TF access-related bleeding — the FEMORAL scale was proposed. Methods: OCEAN RACE is prospective, randomised, open-label, clinical trial...
High platelet reactivity (HPR) and presence of CYP2C19 loss-of-function alleles are associated with higher risk for periprocedural myocardial infarction in clopidogrel-treated patients undergoing percutaneous coronary intervention (PCI). It is unknown whether personalised treatment based on function testing or genotyping can prevent such complications.The ONSIDE-TEST a multicentre, prospective, open-label, randomised controlled clinical trial aiming to assess if optimisation antiplatelet...
To evaluate the feasibility of three-vessel three-dimensional (3D) quantitative coronary angiography (QCA)-based fractional flow reserve (FFR) computation in patients discussed within Heart Team whom treatment decision was based on alone, and to concordance between 3D QCA-based vessel FFR (vFFR)-confirmed functional lesion significance revascularisation strategy as proposed by Team.