A5042981707- Lipoproteins and Cardiovascular Health
- Pesticide Exposure and Toxicity
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer, Lipids, and Metabolism
- MicroRNA in disease regulation
- Galectins and Cancer Biology
- Hormonal Regulation and Hypertension
- Analytical Methods in Pharmaceuticals
- Diet and metabolism studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Analytical Chemistry and Chromatography
- Acute Myocardial Infarction Research
- Circular RNAs in diseases
- Mitochondrial Function and Pathology
- Vitamin D Research Studies
- Adipose Tissue and Metabolism
- Cholinesterase and Neurodegenerative Diseases
- Atrial Fibrillation Management and Outcomes
- Vitamin C and Antioxidants Research
- Pituitary Gland Disorders and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Antioxidant Activity and Oxidative Stress
- Cancer-related molecular mechanisms research
- Folate and B Vitamins Research
- Peptidase Inhibition and Analysis
Medical University of Warsaw
2015-2024
Polskie Towarzystwo Gastroenterologii
2012-2020
Uczelnia Łazarskiego
2020
Institute of Cardiology
1992-2009
Instytut Matki i Dziecka
1992-2007
St.Petersburg V.M.Bekhterev Psychoneurological Research Institute
1980
In Poland there are still nearly 20 million individuals with hypercholesterolaemia, most of them unaware their condition; that is also why only ca. 5% patients familial hypercholesterolaemia have been diagnosed; other rare cholesterol metabolism disorders so rarely diagnosed in Poland. Let us hope these guidelines, being an effect work experts representing 6 main scientific societies, as well the network PoLA lipid centers a part EAS centers, certification lipidologists by PoLA, or growing...
Lipid disorders are the most common (even 70%) and worst monitored cardiovascular risk factor (only 1/4 of patients in Poland CEE countries on LDL-C goal). In order to improve this clear easy implement diagnostic criteria for all components lipid profile should be introduced. These updated guidelines two main scientific societies area - Polish Society Laboratory Diagnostics (PSLD) Association (PoLA), which, comparison those from 2020, introduce few important changes recommendations (two...
Altered expression of cell adhesion molecules (CAMs) has been implicated in a variety chronic inflammatory conditions, including atherosclerosis. Regulation molecule by specific redox-sensitive mechanisms reported. Additionally, it observed that the extract Aronia melanocarpa (A. Melanocarpa) fruits, rich polyphenols, exhibits potent anti-oxidant properties and displays cardioprotective activity.Human aortic endothelial cells (HAECs) were pretreated with various concentrations (primarily 50...
1. Banach M, Jankowski P, Jóżwiak J, et al. (2017). PoLA/CFPiP/PCS guidelines for the management of dyslipidaemias family physicians 2016 Arch Med Sci. 13: 1-45. Google Scholar
Left ventricular (LV) dysfunction after acute myocardial infarction (AMI) is associated with an increased risk of heart failure (HF) development. Diverse microRNAs (miRNAs) have been shown to appear in the bloodstream following various cardiovascular events. The aim this study was identify prognostic miRNAs LV AMI. Patients were divided into subgroups comprising patients who developed or not within six months infarction. miRNA profiles determined plasma and serum samples on first day Levels...
The biochemical confirmation of myocardial infarction is based on cardiac troponin (cTnI or cTnT) determination. Recent scientific results suggested that microRNAs (miRNAs) might become a new biomarker tissue injury.To evaluate the release kinetics circulating heart-specific miRNA-208a and also to test hypothesis can serve as an accessible, diagnostically sensitive plasma ST-elevation acute (STEMI).Nineteen STEMI patients (four women 15 men, aged 44-85 years), 12 with stable coronary artery...
Mycophenolate mofetil (MMF) has beneficial effects in cardiac transplant patients beyond the suppression of tissue rejection. Moreover, mycophenolic acid (MPA), its active metabolite, been associated with positive on atherosclerosis animal models. The attachment leukocytes to vascular endothelium and subsequent migration these cells into vessel wall are early events inflammation atherosclerosis. aim this study was investigate MPA tumour necrosis-α (TNF-α)-induced, endothelial cell...
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Background. Galectin-3 (Gal-3) as a biomarker of fibrosis and inflammation has been implicated in the development progression heart failure (HF) may predict increased morbidity mortality society.Objectives. In this preliminary report we investigated utility novel serum marker for diagnosis acute HF (AHF).Material Methods. The study involved 14 AHF patients aged 67.0 ± 14.6 yrs. with left ventricular ejection fraction (LVEF) 29.29 10.73%, hospitalized at Intensive Coronary Care Unit, where...
Today no established biomarkers are available for the early diagnosis of takotsubo syndrome and its differentiation from ST-segment elevation myocardial infarction. We hypothesized that copeptin copeptin/NT-proBNP ratio may serve a routine marker combination non-invasive differentiation.The study compared serum concentrations copeptin, troponin I (TnI) NT-proBNP in 19 consecutive women diagnosed with according to Mayo Clinic criteria 10 infarction.Copeptin were significantly lower patients...
Abstract: This paper describes the effect of four organophosphorus insecticides: Dipterex, DDVP, Ronnel and its oxygen analogue on respiration rat brain synaptosomes. Dipterex DDVP in concentrations used, 5, 50, or 500 μM, did not change rate uptake oxidative phosphorylation highest concentration (500 μM) inhibited state 3 conditions abolished respiratory control by ADP. inhibition was correlated with a cytochrome c oxidase activity. The (OAR) micromolar (50 increased synaptosomes utilizing...
Myeloperoxidase (MPO) and C-reactive protein (CRP) may play critical roles in generation of oxidative stress the development systemic inflammatory response. The aim study was to determine effect atorvastatin therapy on MPO gene expression its plasma level relation lipids lowering an anti-inflammatory response patients after acute myocardial infarction. research material represented by 112 samples. Thirty-eight with first AMI receiving (40 mg/day) followed up for one month were involved...
To characterize endothelin-1 inactivating peptidase (ET-1 peptidase) recently isolated from rat kidney.ET-1 was purified the membranes of whole Wistar-Kyoto (WKY) kidneys using differential centrifugation, detergent solubilization, ion-exchange chromatography, ultrafiltration and preparative electrophoresis. The enzyme activity in presence increasing concentrations unlabelled peptides, inhibitors other substances determined at pH 5.5 37 degrees C fixed amounts [125I]-ET-1 as substrate.On...