A5001343726- Esophageal and GI Pathology
- Cancer-related molecular mechanisms research
- Reconstructive Surgery and Microvascular Techniques
- Tracheal and airway disorders
- RNA modifications and cancer
- RNA Research and Splicing
- Salivary Gland Tumors Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Bioinformatics and Genomic Networks
- Head and Neck Cancer Studies
- Oral and Maxillofacial Pathology
- Biomedical Text Mining and Ontologies
- Head and Neck Surgical Oncology
- Machine Learning in Bioinformatics
- Ferroptosis and cancer prognosis
Jiangxi Provincial Cancer Hospital
2020-2025
To investigate the role of translocase outer mitochondrial membrane 40 (TOM40) in oral squamous cell carcinoma (OSCC) with aim identifying new biomarkers or potential therapeutic targets. TOM40 expression level OSCC was evaluated using datasets downloaded from The Cancer Genome Atlas (TCGA), as well clinical data. correlation between and clinicopathological parameters survival were analyzed TCGA. signaling pathways associated identified through gene set enrichment analysis. A network genes...
Abstract Objectives To evaluate the diagnostic performance of Milan system for reporting salivary gland cytopathology (MSRSGC) in two southern China tertiary cancer centers and investigate impact rapid on‐site evaluation (ROSE) on FNAC performance. Materials Methods Five hundred forty‐nine patients who underwent lesions with surgical follow‐up from were enrolled this retrospective cohort study. All slides recategorized using MSRSGC after consensus criteria each category. The was evaluated...
For determining pathways and key genes that have relation with development of ATC, differentially expressed (DEGs) from GSE33630 as well GSE65144 expression microarray were screened. Furthermore, we also worked on carrying out the task constructing a protein-protein interaction (PPI) network work weighing gene coexpression (WGCNA). DAVID was utilized for performance Gene Ontology (GO) KEGG pathway enrichment analyses DEGs. We used TCGA THCA data GSE53072 to further verify hub pathway.
A refractory cervical anastomotic fistula which postoperatively remains unhealed for more than 2 months under conservative care severely impacts the quality of life patient and potentially leads to stricture after heals. It is widely accepted that, avoid this complication, fistulas should undergo aggressive treatments. However, when surgical intervention be considered unclear.This study was designed evaluate role pectoralis major myocutaneous flap in management based on our experience 6...
To investigate the role of CAB39 in nasopharyngeal carcinoma (NPC) development and examine its expression level NPC tumor samples.Immunohistochemistry staining tissue microarray was conducted to detect protein tissues, clinical significance evaluated. Lentivirus-mediated over-expression designed increase CNE-1 cells. Cell colony formation, cell cycle CCK-8 proliferation experiments were performed compare ability cells with or without over-expression. Western blotting downstream targets...