A5010759202- Retinal Development and Disorders
- Visual perception and processing mechanisms
- Semiconductor Quantum Structures and Devices
- Retinal Diseases and Treatments
- Photoreceptor and optogenetics research
- Retinal Imaging and Analysis
- Neural dynamics and brain function
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Semiconductor materials and devices
- Nanowire Synthesis and Applications
- Hearing, Cochlea, Tinnitus, Genetics
- Quantum and electron transport phenomena
- Soil and Water Nutrient Dynamics
- Neuroscience and Neural Engineering
- Hydrology and Watershed Management Studies
- Color Science and Applications
- Hydrocarbon exploration and reservoir analysis
- Geological Studies and Exploration
- Semiconductor Lasers and Optical Devices
- Photonic and Optical Devices
- Ocular and Laser Science Research
- Tactile and Sensory Interactions
- Quantum Dots Synthesis And Properties
- Flood Risk Assessment and Management
STZ eyetrial
2012-2022
University of Tübingen
2007-2022
Universität Trier
2004-2016
He Eye Hospital
2008
TH Bingen University of Applied Sciences
2008
Universitäts-Augenklinik Bonn
1992-1997
Max Planck Society
1994-1997
Max Planck Institute for Solid State Research
1993-1996
Philipps University of Marburg
1996
Forschungszentrum Jülich
1992
Usher syndrome (USH), the most prevalent cause of hereditary deafness–blindness, is an autosomal recessive and genetically heterogeneous disorder. Three clinical subtypes (USH1–3) are distinguishable based on severity sensorineural hearing impairment, presence or absence vestibular dysfunction, age onset retinitis pigmentosa. A total 10 causal genes, 6 for USH1, 3 USH2, 1 USH3, USH2 modifier gene, have been identified. robust molecular diagnosis required not only to improve genetic...
We have prepared small InP islands which are embedded in In0.485Ga0.515P grown on a (100) GaAs substrate by solid-source molecular beam epitaxy. The form due to the 3.7% lattice mismatch between and InP. Atomic force microscopy measurements show that island size is typically ∼50 nm diameter ∼5 height for nominally two monolayers of deposited In0.485Ga0.515P. energy photoluminescence (PL) peak shifts from 1.85 1.53 eV as nominal thickness increases 2 10 monolayers. A minimum PL linewidth 21.6...
To evaluate differences in the visual phenotype and natural history of Usher syndrome caused by mutations MYO7A or USH2A, most commonly affected genes Type I (USH1) II (USH2), respectively.Eighty-eight patients with a clinical diagnosis USH1 (26 patients) USH2 (62 were retrospectively evaluated. Of these, 48 had 2 disease-causing (10 patients), USH2A (33 other USH (5 genes. Clinical investigation included best-corrected acuity, Goldmann field, fundus photography, electroretinography,...
Optical gain measurements have been performed on self-assembled InP quantum dots embedded in GaInP. The are formed during the growth of GaInP by molecular beam epitaxy due to strong lattice mismatch and overgrown with afterwards. optical spectra show two peaks which could be clearly identified their polarization properties as being wetting layer, respectively. As expected from results measurements, pumping cleaved samples at room temperature leads lasing either or depending experimental conditions.
The aim of this study was to characterize the ophthalmic and genetic features Bardet Biedl (BBS) syndrome in a cohort patients from German specialized care center. Sixty-one patients, aged 5–56 years, underwent detailed examination including visual acuity color vision testing, electroretinography (ERG), visually evoked potential recording (VEP), fundus examination, spectral domain optical coherence tomography (SD-OCT). Adaptive optics flood illumination ophthalmoscopy performed five...
The aim of this study was to investigate the effects an increase in saturation blood oxygen (SaO 2 ) and/or serum glucose on photoreceptor sensitivity normal subjects and patients with diabetes mellitus. We monitored cone rod by recording dark-adaptation curves both green red test stimuli while inhaling either air (20% O + 80% N or 100% 12 diabetic no (10) mild (2) retinopathy. also repeated experiment 10 under hyperglycemia (mean glucose: 161 mg/dl). Results show that dark-adapted is...
<h3>AIMS</h3> To examine the colour vision of juvenile patients suffering from diabetes mellitus without retinopathy in relation to metabolic and ophthalmic state. <h3>METHODS</h3> Metameric matches, both Rayleigh (red/green) Moreland (blue/green) were used test yearly 10 patients. The monitored over 4 years, during final year, their blood glucose level was determined directly after testing vision. An examination performed on day urine analysed regularly throughout years. Their results are...
Diffuse reflectance infrared Fourier transform (DRIFT) spectrometry was applied to a set of sediment samples collected by traps over one and half years in mid-mountainous river. Dynamic changes hydrological life-cycle conditions generated particles different Corg content organic composition. Periods the midst or shortly after flood events left poor with spectral features that were enriched carboxylic aromatic signals. These are characteristic terrestrial oxidized vascular plant debris....
We report on the investigation of exciton relaxation, as traced by time-resolved photoluminescence, in nanoscale InP islands embedded an ${\mathrm{In}}_{0.48}$${\mathrm{Ga}}_{0.52}$P matrix. Excitons are generated excited, high-energy states. Depending excitation energy, up to three LO-phonon replicas into lower-energy states observed. The rise all phonon replicas, which we attribute emission time, is faster than 10 ps, our time resolution. Their $\frac{1}{e}$ decay times, acoustical-phonon...
purpose. To perform a detailed topographical analysis of functional age-related changes over the retina. methods. Fifty-nine normal phakic subjects aged 10 to 69 years were divided into six groups, according decade age. mfERG traces recorded from central 60° retina, with resolution 61 and 103 scaled hexagons. Group medians peak amplitude latency first- second-order (first slice) responses used generate 3-D maps. results. With age, there was continuous loss delay implicit time response...