A5084543956- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Ophthalmology and Eye Disorders
- Migraine and Headache Studies
- Glaucoma and retinal disorders
- Neural dynamics and brain function
- Cerebral Venous Sinus Thrombosis
- Obstructive Sleep Apnea Research
- Bone health and treatments
- Cancer Diagnosis and Treatment
- Ear Surgery and Otitis Media
- Hearing Loss and Rehabilitation
- Cardiovascular Syncope and Autonomic Disorders
- Visual perception and processing mechanisms
- Retinal Development and Disorders
- Multisensory perception and integration
- Parkinson's Disease Mechanisms and Treatments
- Hearing Impairment and Communication
- Motor Control and Adaptation
- Hereditary Neurological Disorders
- Connexins and lens biology
- Hemispheric Asymmetry in Neuroscience
- Facial Nerve Paralysis Treatment and Research
- Paraoxonase enzyme and polymorphisms
- Virtual Reality Applications and Impacts
University of Naples Federico II
2011-2025
Ospedale San Giovanni Bosco
2016-2021
University of Campania "Luigi Vanvitelli"
2014
University of Salerno
2014
Hermitage Museum
2014
Maastricht University
2014
Ospedale San Filippo Neri
2014
Lega Italiana per la Lotta ai Tumori
2006
Federico II University Hospital
1997
<h3>Objective:</h3> To investigate the functional response of neural pathways associated with vestibular stimulation in patients migraine (VM). <h3>Methods:</h3> Twelve VM underwent whole-brain blood oxygen level–dependent (BOLD) fMRI during ear irrigation cold water. The to this was compared age- and sex-matched without aura healthy controls. Secondary analyses explored associations between BOLD signal change clinical features patients. <h3>Results:</h3> We observed a robust cortical...
The objective of this study was to evaluate hearing impairment in patients affected by Parkinson's disease compared with scores observed normal age- and sex-matched controls. One hundred eighteen consecutive a clinical diagnosis were screened. Severity motor symptoms staging measured the Unified Disease Rating Scale (section III) Hoehn Yahr scale. Audiometric evaluation consisted comprehensive audiologic case history questionnaire, visual otoscopic examination, acoustic immittance measures...
Objective.—The study explored the hypothesis that spontaneous nystagmus (Ny) in migraine patients can be triggered or modulated by painful trigeminal stimulation, providing evidence of a functional connection between vestibular and systems. Background.—Vertigo attacks are reported subjects with familiar history migraine, also independently headache episodes. Idiopathic vertigo is three times more frequent than controls. Vestibular investigations have consistently demonstrated Ny both central...
Abstract Lateral trunk flexion is a very common clinical observation in patients affected by Parkinson's disease. Postural control known to depend on vestibular, visual, and somatosensory information. The aim of this study was investigate whether impairment vestibular function can account for the postural alterations observed parkinsonian with lateral flexion. We evaluated 11 age‐, sex‐, disease duration–matched without following tests were performed: infrared videonystagmography including...
Abstract Background: Noise-induced cochlear epithelium damage can cause hearing loss in industrial workers. In experimental systems, noise induces the release of free radicals and may sensorial epithelium. Therefore, genes involved regulating reactive oxygen species manganese-superoxide dismutase (SOD2) antioxidant paraoxonase (PON) could influence cochlea vulnerability to noise. We evaluated whether susceptibility noise-induced (NIHL) is associated with SOD2, PON1, PON2 polymorphisms...
Objectives/Hypothesis The need for class I and II studies on the efficacy of liberatory maneuvers in treatment lateral canal benign paroxysmal positional vertigo (LC‐BPPV) motivated present double‐blind randomized trial short‐term Gufoni maneuver (GLM). Study Design Double‐blind controlled trial. Methods Seventy‐two patients with unilateral LC‐BPPV were recruited a multicentric study. Patients randomly assigned to by GLM (n = 37) or sham 35). Subjects followed up twice (at 1 hour 24 hours)...
To evaluate differences in the visual phenotype and natural history of Usher syndrome caused by mutations MYO7A or USH2A, most commonly affected genes Type I (USH1) II (USH2), respectively.Eighty-eight patients with a clinical diagnosis USH1 (26 patients) USH2 (62 were retrospectively evaluated. Of these, 48 had 2 disease-causing (10 patients), USH2A (33 other USH (5 genes. Clinical investigation included best-corrected acuity, Goldmann field, fundus photography, electroretinography,...
To assess, during symptom free intervals, the clinical, audiological, and vestibular findings in a cohort of child migraine sufferers, with or without vertigo dizziness both.In adults children, are frequently associated migraine.Twenty-two sufferers symptoms, aged 7-13 years (group A), 18 8-13 B) entered our study between January 2007 June 2007. The characteristics auditory functions symptoms signs were assessed reviewed by blinded physician.The whole sample was found audiologically normal....
Background: The diagnosis of benign paroxysmal positional vertigo (BPPV) involving the lateral semicircular canal (LSC) is traditionally entrusted to supine head roll test, also known as yaw test (SHYT), which usually allows identification pathologic side and BPPV form (geotropic vs. apogeotropic). Nevertheless, SHYT may not always allow easy detection affected canal, resulting in similar responses on both sides intense autonomic symptoms patients with recent onset vertigo. newly introduced...
Several studies in children with neurodevelopmental disorders (NDDs) including autism spectrum (ASDs), reading impairment, or attention deficit/hyperactive disorder (ADHD) pointed toward a potential dysfunction of the vestibular system, specifically its complex relationship cerebellum. The aim present study was to test functional vestibulo-ocular reflex (VOR) responses NDDs measure performance system. VOR is involved this stabilization image on retina during rapid movements head. To perform...
Benign paroxysmal positional vertigo (BPPV) usually has a favorable course, although it is possible to observe BPPV with high recurrence rate. Previous studies suggested that vitamin D deficiency might affect recurrences, and oxidative stress play complementary role in pathogenesis. This multicentric trial aimed evaluate the effectiveness of oral nutritional supplementation compound alpha-lipoic acid, Carnosine, Zinc (LICA® (Difass International, Coriano (RN), Italy)), vitamins group B...
The objective was to evaluate nystagmus intensity and direction (NID) during bow lean test (BLT) in subjects suffering from idiopathic lateral semicircular canal benign paroxysmal positional vertigo (LSC-BPPV), order differentiate between the geotropic apogeotropic form determine affected ear before using classic diagnostic procedures. BLT performed 32 by LSC-BPPV. "Nystagmus intensity" evaluation allows distinguishing variant one, while "nystagmus direction" identification of side. In...
Abstract Introduction Benign paroxysmal positional vertigo (BPPV) of the horizontal semicircular canal (hSCC) can present with otoconia blocking its lumen (canalith jam), signs and symptoms that make it difficult to distinguish from central nervous system pathology. Objective Here we report two cases canalith jam affecting hSCC offer a theoretical mechanism based on known vestibular neurophysiology. Methods We use video‐oculography document show moment loosen. Results Canalith is rare form...
Objectives/Hypothesis The need for class I and II studies on the efficacy of liberatory maneuvers in treatment lateral canal benign paroxysmal positional vertigo (LC‐BPPV) motivated present double‐blind randomized trial short‐term forced prolonged position (FPP). Study Design Double‐blind, controlled trial. Methods Two hundred twenty‐one patients with unilateral LC‐BPPV met inclusion criteria a multicentric study. Patients were randomly assigned to by FPP (116 subjects) or sham (105...
Aim The aim of this article is to explore the progression neurological, neuro-otological and cochlear features in benign paroxysmal vertigo (BPV) children over time its relation with migraine, disorders adulthood. Methods From January 2002 December 2002, 15 BPV were prospectively recruited then evaluated during a 10-year observational follow-up. All patients underwent detailed examinations interictal phases. Six also studied ictal periods. Results At first assessment, four reported migraine...
To assess if a polyphenol compound supplementation (Vertigoval®) could improve residual dizziness earlier after benign paroxysmal positional vertigo (BPPV) and relieve patients from this disabling symptomatology.In prospective, multicentric study, 127 were randomized in the treatment group (TG), who received 60-day supplementation, while 131 control (CG), did not receive any medication. The handicap inventory (DHI) score, static posturography, visual analog scale (VAS) for both (D-VAS)...