A5086246161- Vestibular and auditory disorders
- Ophthalmology and Eye Disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Glaucoma and retinal disorders
- Cerebral Venous Sinus Thrombosis
- Ear Surgery and Otitis Media
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Facial Nerve Paralysis Treatment and Research
- Cerebrovascular and Carotid Artery Diseases
- Obstructive Sleep Apnea Research
- Migraine and Headache Studies
- Tracheal and airway disorders
- Botulinum Toxin and Related Neurological Disorders
- Meningioma and schwannoma management
- Olfactory and Sensory Function Studies
- Soft tissue tumor case studies
- Acupuncture Treatment Research Studies
- Musculoskeletal pain and rehabilitation
- Balance, Gait, and Falls Prevention
- Head and Neck Cancer Studies
- Tumors and Oncological Cases
- Cardiovascular Syncope and Autonomic Disorders
- Peripheral Nerve Disorders
University of Pisa
2013-2024
Azienda Ospedaliera Universitaria Pisana
2015-2024
Fondazione Stella Maris
2024
Pierre Fabre (Germany)
2021
Fondazione Umberto Di Mario
2016
University of Westminster
2015
Charing Cross Hospital
2015
Ospedale Santa Chiara
2004
Neuroscience Institute
2001
The horizontal semicircular canal variant of paroxysmal positional vertigo (HSC-PPV) shows three subtype nystagmic patterns: 1) bilateral geotropic nystagmus, 2) apogeotropic nystagmus that may switch into geotropic, and 3) never switches geotropic. In recent years, many methods physical treatment have been proposed for HSC-PPV, yet no standard protocol has defined. We studied the effects different according to each form HSC-PPV after a precise definition clinical features.A prospective...
Objective The aim of this work was to assess through a questionnaire the features vertiginous episodes, accompanying symptoms, familial history, and migraine precursors in sample 252 subjects with diagnosis definite vestibular migraine. Background Migraine is common neurological disorder characterized by episodic headaches specific features. About two‐thirds cases run families, patients may refer symptoms occurring infancy childhood, defined as syndromes that be associated vertigo, called...
Objective To determine the efficacy and safety of low‐dose intratympanic gentamicin (ITG) compared with dexamethasone (ITD) in patients intractable unilateral Ménière disease (MD). Study Design Open prospective randomized controlled study. Setting Tertiary referral center. Subjects Methods Sixty affected by definite MD were enrolled between January 1, 2007, June 30, 2008. Thirty‐two treated a buffered solution injected middle ear (maximum 2 injections); 28 ITD (4 mg/mL, 3 injections at...
The aim of this study is to compare the results obtained using 2 methods treatment for horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV): barbecue maneuver + forced prolonged position (FPP) versus Gufoni maneuver. In a randomized prospective clinical trial, we recruited 147 patients affected by HSC-BPPV. primary outcome was absence and nystagmus upon application supine roll test during follow-up examination. A statistical evaluation performed in order assess...
Objectives/Hypothesis The need for class I and II studies on the efficacy of liberatory maneuvers in treatment lateral canal benign paroxysmal positional vertigo (LC‐BPPV) motivated present double‐blind randomized trial short‐term Gufoni maneuver (GLM). Study Design Double‐blind controlled trial. Methods Seventy‐two patients with unilateral LC‐BPPV were recruited a multicentric study. Patients randomly assigned to by GLM (n = 37) or sham 35). Subjects followed up twice (at 1 hour 24 hours)...
Although cerebral small vessel disease is a significant contributor to the development of imbalance and falls in elderly, whether it causes dizziness not known.A retrospective case analysis was conducted for 122 dizzy patients referred two neuro-otology tertiary centres London Pisa. Patients were divided into 'explained' (e.g. benign positional vertigo, vestibular neuritis, orthostatic hypotension, cerebellar ataxias) 'unexplained' dizziness. White matter hyperintensities (WMH) MRI (T2...
To evaluate the neurotologic findings in patient suffering from migraine with and without vestibular symptoms.Comparative cross-sectional observational study.Tertiary referral center.Migraine headache is often associated other symptoms, including dizziness, head motion intolerance, or rotational-type vertigo. The neuro-otologic examination migrainous patients gives unremarkable results. date, it not fully understood why some complain of symptoms do not, yet clear whether abnormalities among...
To describe the clinical and oculographic features in patients with anterior semicircular canal benign paroxysmal positional vertigo to determine efficacy of a canalith repositioning procedure for its management.Case series chart review presenting downbeating nystagmus during 2-year period.Outpatients' tertiary referral center balance disorders.Eighteen suffering from were treated maneuver based on modification proposed by Crevits.disappearance nystagmus.Positional was elicited unilaterally...
Background: Treatment of sudden hearing loss is a significant matter discussion. Lack knowledge the natural history disease and use different success criteria are 2 main reasons why it difficult to critically evaluate data available in literature. To date, no therapy has proved effective according evidence criteria. However, there been trend toward steroids recent years. The management patients who fail respond standard even more complex; these cases, intratympanic have proposed as valuable...
La vertigine parossistica posizionale benigna (VPPB) è il tipo più comune di periferica. Frequentemente dopo primo episodio la VPPB presenta recidive, con un tasso ricorrenza tra 15% ed 50%. Ad oggi non vi chiarezza sui processi eziopatogenetici che portano al distacco degli otoconi né su quali siano i fattori rendono una patologia recidivante, ma recenti studi epidemiologici hanno evidenziato possibile associazione rischio cardiovascolari. Lo scopo del presente studio (Sesto Senso Survey)...
Objectives (1) To describe the relationships among main instrumental features characterizing an acute unilateral vestibulopathy and (2) to clarify role of video head impulse test in predicting development chronic vestibular insufficiency. Study Design Case series with chart review. Setting Tertiary referral center. Subjects Methods Sixty patients suffering from were retrospectively analyzed: 30 who recovered spontaneously (group 1) needed a rehabilitation program 2). The outcome measures...
Objective To determine the prevalence of cases missed cerebellar stroke mimicking acute peripheral vertigo (APV), so‐called pseudo‐APV, and to identify clinical indicators useful for differentiating APV from infarction that presents as isolated vertigo. Study Design Case series with chart review. Setting Tertiary referral center. Subjects Methods We conducted a retrospective review over past 5 years. All patients had first undergone an otoneurological evaluation computed tomography brain...
(1) To compare the results of 2 regimens treatment at 2-year follow-up and (2) to evaluate need efficacy retreatment after recurrence vertigo attacks in a longer period (using Kaplan-Meier method analysis).Retrospective chart review.Tertiary referral center.We analyzed 77 patients treated with intratympanic gentamicin (ITG). Thirty-five were high-dose (HD) ITG (in total 6 injections, twice day, repeated every 3 days) 42 low-dose (LD) (1-2 injections). The evaluated terms functional level...
Objectives: To analyze and compare, in two groups of patients affected by definite Ménière's disease (MD) but treated differently, the Video Head Impulse Test findings especially putting them relationship with canal paresis, hearing loss, duration disease. Study Design: Retrospective chart review. Patients: Seventy unilateral MD (16 Group 1 54 2) observed between March 2014 May 2015 a tertiary referral center were retrospectively studied then divided into groups: was previously intratympanic...
To assess, in patients referred to vestibular rehabilitation (VR) for persistence of disability after acute unilateral vestibulopathy (AUV), whether the video head impulse test (vHIT) can be a useful technique define efficacy treatment.Prospective clinical study.Tertiary academic referral hospitals.Thirty with residual symptoms AUV were included.Patients underwent 10-week VR program.Evaluation dizziness handicap inventory score, high-velocity vestibulo-ocular reflex gain, asymmetry index,...
Given a sufficiently provocative stimulus, almost everyone can be made motion sick, with approximately one-third experiencing significant symptoms on long bus trips, ships, or in light aircraft.1–4 Current countermeasures are either behavioral pharmacologic. Behavioral measures include habituation/desensitization treatment protocols5 as well positioning the head alignment direction of gravito-inertial force and maintaining stable horizontal reference frame.5 Pharmacologic antimuscarinics, H1...
Objectives/Hypothesis To evaluate the clinical features of audiologic impairment and its relationship with nasal, vestibular, rheumatologic profile in a cohort patients eosinophilic granulomatosis polyangiitis (EGPA), formerly named Churg‐Strauss syndrome. Study Design Prospective cross‐sectional study. Methods Thirty‐nine EGPA, considered controlled according to Birmingham Vasculitis Activity Score Damage Index, underwent complete evalutaion otomicroscopy, impedance audiometry, speech...