A5087987306- Multiple Sclerosis Research Studies
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Peripheral Neuropathies and Disorders
- Polyomavirus and related diseases
- Restless Legs Syndrome Research
- SARS-CoV-2 and COVID-19 Research
- Acute Lymphoblastic Leukemia research
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Long-Term Effects of COVID-19
- Botulinum Toxin and Related Neurological Disorders
- Systemic Sclerosis and Related Diseases
- Autism Spectrum Disorder Research
- Retinal and Optic Conditions
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Telemedicine and Telehealth Implementation
- Advanced Neuroimaging Techniques and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Dementia and Cognitive Impairment Research
- Neurological diseases and metabolism
- Health Literacy and Information Accessibility
- Olfactory and Sensory Function Studies
- Viral Infections and Immunology Research
Federico II University Hospital
2016-2025
University of Naples Federico II
2016-2025
University College London
2016-2024
National Hospital for Neurology and Neurosurgery
2017-2024
Queen Mary University of London
2018-2024
University Medical Center of the Johannes Gutenberg University Mainz
2024
Johannes Gutenberg University Mainz
2024
Associazione Italiana Sclerosi Multipla
2023
Institute for Health Metrics and Evaluation
2023
National Institute for Health Research
2020-2021
Abstract Background ChatGPT is an open-source natural language processing software that replies to users’ queries. We conducted a cross-sectional study assess people living with Multiple Sclerosis’ (PwMS) preferences, satisfaction, and empathy toward two alternate responses four frequently-asked questions, one authored by group of neurologists, the other ChatGPT. Methods An online form was sent through digital communication platforms. PwMS were blind author each response asked express their...
The variability in the clinical phenotype of Parkinson's disease seems to suggest existence several subtypes disease. To test this hypothesis we performed a cluster analysis using data assessing both motor and non-motor symptoms large cohort newly diagnosed untreated PD patients.We collected on demographic, motor, whole complex from 100 consecutive outpatients. Statistical allowed identification different subgroups, which have been subsequently explored.The driven approach identified four...
Cognitive impairment occurs from the early phases of multiple sclerosis (MS), and more frequently affects secondary progressive (SP) subjects than relapsing-remitting (RR).To investigate relationships between cognitive dysfunctions in newly diagnosed RRMS, long-term MS-related outcomes.The present 10-year retrospective longitudinal study included 155 RRMS subjects, tested with Rao Brief Repeatable Battery at MS diagnosis. The reaching Expanded Disability Status Scale (EDSS) 4.0, SP...
The objective of this study was to evaluate hearing impairment in patients affected by Parkinson's disease compared with scores observed normal age- and sex-matched controls. One hundred eighteen consecutive a clinical diagnosis were screened. Severity motor symptoms staging measured the Unified Disease Rating Scale (section III) Hoehn Yahr scale. Audiometric evaluation consisted comprehensive audiologic case history questionnaire, visual otoscopic examination, acoustic immittance measures...
Background: Optical coherence tomography (OCT) angiography is a new method to assess the density of vascular networks. Vascular abnormalities are considered involved in multiple sclerosis (MS) pathology. Objective: To presence MS and evaluate their correlation disease features. Methods: A total 50 patients with without history optic neuritis (ON) 46 healthy subjects were included. All underwent spectral domain (SD)-OCT OCT angiography. Clinical history, Expanded Disability Status Scale...
<h3>Background</h3> Non-motor symptoms are very common among patients with Parkinson9s disease since the earliest stage, but little is known about their progression and relationship dopaminergic replacement therapy. <h3>Methods</h3> We studied non-motor before after 2 years from therapy introduction in ninety-one newly diagnosed previously untreated PD patients. <h3>Results</h3> At baseline, nearly all (97.8%) referred at least one symptom. follow-up, only few significantly changed....
Background and purpose Very little is known about the progression of non‐motor symptoms ( NMSs ) in Parkinson's disease PD there are no longitudinal studies exploring this topic from earliest stage, when patients receive diagnosis. We here report on over 4 years diagnosis a cohort de‐novo , previously untreated, with . Methods Consecutive (disease duration < 2 years), untreated were enrolled observational study. Evaluations then scheduled every included assessment motor features as well...
Restless legs syndrome (RLS) prevalence estimates range from 0% to 52% in Parkinson disease (PD), but the causal relationship between two disorders is still debated. The present study aims evaluate RLS de novo PD subjects, its incidence during first 4 years diagnosis, and possible relationships with clinical, laboratory, neuroradiological data.One hundred nine newly diagnosed, drug-naïve subjects were evaluated at time of after 2- 4-years. diagnosis was performed Diagnostic Index each visit....
Background: Longitudinal studies on healthy participants have shown that subjective memory impairment (defined as cognitive complaints with normal objective performance) might be a strong predictor of mild (MCI). Parkinson disease (PD) also manifests disturbances, but whether may predict the development MCI in PD has not yet been explored. Methods: We prospectively screened newly diagnosed, untreated patients order to evaluate over 2-year follow-up evaluation. Results: enrolled 76 de novo...
To estimate the prevalence of Pisa syndrome (PS) in patients with Parkinson disease (PD) and to assess association between PS demographic clinical variables.In this multicenter cross-sectional study, consecutive outpatients PD attending 21 movement disorders Italian tertiary centers were enrolled underwent standardized evaluation. was defined as trunk lateral deviation ≥10°. Patients compared according presence for several variables.Among 1,631 PD, detected 143 (8.8%, 95% confidence interval...
Background and purpose Cardiovascular risk factors can increase the of multiple sclerosis ( MS ) modify its course. However, such possibly interact, determining a global cardiovascular risk. Our aim was to compare subjects with without simplified 10‐year Framingham General Disease Risk Score FR evaluate importance on ‐related outcomes. Methods Age, gender, smoking status, body mass index, systolic blood pressure, type II diabetes use antihypertensive medications were recorded in estimate ,...