A5074170004- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Polyomavirus and related diseases
- Genetic Neurodegenerative Diseases
- Telemedicine and Telehealth Implementation
- Health Systems, Economic Evaluations, Quality of Life
- Transcranial Magnetic Stimulation Studies
- Pharmaceutical industry and healthcare
- Mitochondrial Function and Pathology
- Immunotherapy and Immune Responses
- Chronic Lymphocytic Leukemia Research
- Psoriasis: Treatment and Pathogenesis
- Artificial Intelligence in Healthcare and Education
- Neurogenetic and Muscular Disorders Research
- Sphingolipid Metabolism and Signaling
- MicroRNA in disease regulation
- Amyotrophic Lateral Sclerosis Research
- Autoimmune and Inflammatory Disorders Research
- Clinical Reasoning and Diagnostic Skills
- Ethics in Clinical Research
- Long-Term Effects of COVID-19
- Inflammatory Myopathies and Dermatomyositis
- RNA regulation and disease
- Inflammasome and immune disorders
- Research on Leishmaniasis Studies
University of Campania "Luigi Vanvitelli"
2021-2024
Medical University of Vienna
1982
Abstract Background ChatGPT is an open-source natural language processing software that replies to users’ queries. We conducted a cross-sectional study assess people living with Multiple Sclerosis’ (PwMS) preferences, satisfaction, and empathy toward two alternate responses four frequently-asked questions, one authored by group of neurologists, the other ChatGPT. Methods An online form was sent through digital communication platforms. PwMS were blind author each response asked express their...
Cladribine administration has been approved for the treatment of relapsing-remitting multiple sclerosis (MS) in 2017; thus, data on cladribine a real-world setting are still emerging.We report effectiveness, safety profile, and response predictors 243 patients with MS followed at eight tertiary centers. Study outcomes were: (1) No Evidence Disease Activity-3 (NEDA-3) status its components (absence clinical relapses, MRI activity, sustained disability worsening); (2) development grade III/IV...
Abstract Background Multiple sclerosis (MS) and psoriasis (PsO) are distinct chronic autoimmune conditions with varying impacts on patients' lives. While the co-occurrence of MS PsO has been reported, underlying pathogenic link remains unclear. This study aimed to investigate prevalence in a outpatient clinic population explore potential interplay between these conditions. Methods 316 patients who had at least one visit our center last year, were selected from Clinic electronic database...
Background: Neuromuscular electrical stimulation (NMES) has beneficial effects on physical functions in Multiple Sclerosis (MS) patients. However, the neurophysiological mechanisms underlying these functional improvements are still unclear. This study aims at comparing acute responses spinal excitability, as measured by soleus Hoffmann reflex (H-reflex), between MS patients and healthy individuals, following three experimental conditions involving ankle planta flexor muscles: 1) passive NMES...
Abstract Introduction People with multiple sclerosis (PwMS) exhibit a spectrum of needs that extend beyond solely disease-related determinants. Investigating unmet from the patient perspective may address daily difficulties and optimize care. Our aim was to identify patterns among PwMS their Methods We conducted cross-sectional multicentre study. Data were collected through an anonymous, self-administered online form. To cluster according main needs, we performed agglomerative hierarchical...
Background: over the past 20 years, treatment scenario of multiple sclerosis (MS) has radically changed and an ever-increasing number disease-modifying treatments emerged. Among high efficacy agents, monoclonal antibodies (mAbs) have become a mainstay in MS patient’s due to their targeted mechanism, favorable risk profile. The latter varies from drug skin cancer warning emerged with sphingosine 1-phosphate receptors inhibitors. Several cases malignancy people (pwMS) undergoing therapy mAbs...
Siponimod, a selective modulator of sphingosine 1-phosphate receptors 1 (S1P1) and 5 (S1P5), has recently been marketed for patients with Secondary Progressive Multiple Sclerosis (SPMS). Herein, we report three SPMS presenting disease reactivation in the first months after switching from fingolimod to siponimod. Fingolimod binds S1P1, S1P3, S1P4 S1P5 receptors. S1P3 holds central role eliciting proinflammatory responses, thus it hypothesized that upregulation may be mechanism behind relapses...
In 13 cases referred to psychiatric treatment between 1974 and 1980 acute viral encephalitis was diagnosed in the further course of illness. The majority were female patients. Positive virological or pathological evidence obtained 38% all cases. most frequent etiology be found herpes-simplex virus. These findings correspond 36 from literature.
(1) Background: Neuromuscular electrical stimulation (NMES) has beneficial effects on physical functions in Multiple sclerosis (MS) patients. However, the neurophysiological mechanisms underlying these functional improvements are still unclear. This study aims at comparing acute responses spinal excitability, as measured by soleus Hoffmann reflex (H-reflex), between MS patients and healthy individuals, under three experimental conditions involving ankle planta flexor muscles: passive NMES...
Unlike the consumer industry, biopharma, medical technology, and wellness companies have struggled to build meaningful, personalized patient healthcare professional (HCP) experiences. The increase in drug launches growing competition across therapy areas has made it challenging for brands organizations stand out from crowd, whether new molecules vs. legacy an established treatment area their generic counter-parts or a rare disease where trust is not yet earned. customers’ needs preferences...
The DYSPHAGIA IN MULTIPLE SCLEROSIS (DYMUS) questionnaire is the only specific tool developed to screen for dysphagia in people with Multiple Sclerosis (pwMS). However, some limitations of DYMUS could potentially be addressed by SWALLOWING DISTURBANCE QUESTIONNAIRE (SDQ), which has not yet been validated pwMS. objective this study was translate and validate SDQ into Italian language use pwMS detect swallowing disturbances.