A5025192250- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Natural Antidiabetic Agents Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Cleft Lip and Palate Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Dermatology and Skin Diseases
- Folate and B Vitamins Research
- Inhalation and Respiratory Drug Delivery
- Mycobacterium research and diagnosis
- Curcumin's Biomedical Applications
- Urticaria and Related Conditions
- Head and Neck Cancer Studies
- Peptidase Inhibition and Analysis
- RNA regulation and disease
- Ovarian cancer diagnosis and treatment
University of Campania "Luigi Vanvitelli"
2025
Sapienza University of Rome
1987-2021
University of Ferrara
2010-2011
Oral squamous cell carcinoma, the most frequently occurring malignant head and neck tumour, generally exhibits poor prognosis metastases are main cause of death. The discovery reliable prognostic indicators tumour progression could greatly improve clinical practice. MicroRNAs involved in regulation basic cellular processes such as proliferation, differentiation, apoptosis. Since miRNAs have been shown to be abnormally expressed different tumours their importance potential cancer is...
Summary This report describes a retrospective analysis of the month birth distribution 2124 children with respiratory allergy in Rome district between 1964 and 1985, comparison total live births same over period. Of children, 1685 had positive skin tests or RAST only to mites, 439 grass pollen ( P < 0.001). A significant relationship was found mite sensitization birth. high proportion born June‐September <0.005), even higher that those March‐May sensitivity 0.005), compared years as...
Conventional/targeted chemotherapies and ionizing radiation (IR) are being used both as monotherapies in combination for the treatment of epithelial ovarian cancer (EOC). Several studies show that these therapies might favor oncogenic signaling impede anti-tumor responses. MiR-200c is considered a master regulator EOC-related oncogenes. In this study, we sought to investigate if chemotherapy IR could influence expression miR-200c-3p its target genes, like immune checkpoint PD-L1 other...
Background: Curcumin is a polyphenolic compound derived from the food spice turmeric that has received interest medical and scientific world for its role in management of several conditions. Clinical studies, humans, have shown ingested safe even at high doses (12 g/day), but it poor bioavailability primarily due to absorption rapid metabolism elimination. Several strategies been implemented improve Curcumin, example, combination piperine complex with or usage formulations phospholipid...
Abstract Ovarian cancer is one of the most common gynecological malignancies, ranking third after cervical and uterine cancer. High-grade serous ovarian (HGSOC) aggressive subtype, late onset its symptoms leads in cases to an unfavourable prognosis. Current predictive algorithms used estimate risk having Cancer fail provide sufficient sensitivity specificity be widely clinical practice. The use additional biomarkers or parameters such as age menopausal status overcome these issues showed...
The onset of embryonic malformations is greatly determined by the intrauterine environment, conditioned maternal lifestyle, diet, drugs and medication intake, in addition to both foetal genotypes. Maternal C677T MTHFR genotype has been identified as important factor cleft lip with or without palate (CL/P) etiology. In present study we evaluated possible interaction between methylenetetrahydrofolate reductase (MTHFR) ABCB1 gene codes for a drug-transport pump charge protect cell extruding...
Mild cognitive impairment (MCI) is a transitional clinical stage prior to dementia. Patients with amnestic MCI have high risk of progression toward Alzheimer's disease. Both mild and sporadic disease are multifactorial disorders consequential from multifaceted cross-talk among molecular biological processes. Non-coding RNAs play an important role in the regulation gene expression, mainly long non-coding (lncRNAs), that regulate other RNA transcripts through binding microRNAs. Cross-talk...
miRNA regulatory axes in blood of MCI patients, which includes lncRNA-SNHG16, lncRNA-H19 and lncRNA-NEAT1. Microarray investigations have demonstrated modifications the expression long non-coding RNAs (lncRNA) patients with compared control samples. This is first study to explore lncRNA profiles Mild Cognitive Impairment blood. Our proposes targets involved molecular pathways connected pathogenesis MCI.