A5051117077- Phytochemicals and Medicinal Plants
- Pharmacological Effects of Natural Compounds
- Medicinal Plants and Neuroprotection
- Essential Oils and Antimicrobial Activity
- Curcumin's Biomedical Applications
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Andrographolide Research and Applications
- Moringa oleifera research and applications
- Pharmacological Effects of Medicinal Plants
- Ethnobotanical and Medicinal Plants Studies
- Natural Antidiabetic Agents Studies
- Phytochemistry and Bioactive Compounds
- Cholinesterase and Neurodegenerative Diseases
- Gout, Hyperuricemia, Uric Acid
- Helicobacter pylori-related gastroenterology studies
- Biochemical and Molecular Research
- Medicinal Plant Research
- Diet, Metabolism, and Disease
- Phytochemistry and Biological Activities
- Vitamin C and Antioxidants Research
- Drug-Induced Hepatotoxicity and Protection
- Phytochemistry and biological activity of medicinal plants
- Plant biochemistry and biosynthesis
- Orthopedic Infections and Treatments
All India Institute of Medical Sciences
2025
Thomas Jefferson University
2024
University of Arkansas for Medical Sciences
2006-2024
Arkansas Children's Hospital
2024
Natural Remedies (India)
2012-2022
Bristol-Myers Squibb (United States)
2021
National Institute of Pharmaceutical Education and Research
2009-2011
University of Mississippi
2009
Arkansas Children's Nutrition Center
2006
The fruit of Euterpe oleraceae, commonly known as acai, has been demonstrated to exhibit significantly high antioxidant capacity in vitro, especially for superoxide and peroxyl scavenging, and, therefore, may have possible health benefits. In this study, the capacities freeze-dried acai pulp/skin powder (OptiAcai) were evaluated by different assays with various free radical sources. It was found exceptional activity against scavenging (SOD) assay, highest any food reported date measured...
On the basis of structures known topoisomerase II catalytic inhibitors and initial molecular docking studies, bicyclic N-fused aminoimidazoles were predicted as potential inihibitors. They synthesized by multicomponent reactions evaluated against human IIα (hTopoIIα) in decatenation, relaxation, cleavage complex, DNA intercalation vitro assays. Among 31 compounds eight different scaffolds, it was found that imidazopyridine, imidazopyrazole, imidazopyrazine with suitable substituents...
Pharmacognosy Research,2013,5,2,71-79.DOI:10.4103/0974-8490.110527 Published:April 2013Type:Original Article Authors:Chinampudur V Chandrasekaran, Kannan Sundarajan, Jothie R Edwin, Giligar M Gururaja, Deepak Mundkinajeddu, and Amit Agarwal Author(s) affiliations:Chinampudur D Centre, Natural Remedies Pvt. Ltd., Bangalore, India. Abstract:Background: While curcuminoids have been reported to possess diverse biological activities, the anti-inflammatory activity of polar extracts (devoid...
Curcuma longa is widely known for its anti-inflammatory activity in traditional system of medicine centuries and has been scientifically validated extensively. The present study was conducted to evaluate the curcuminoids oil-free aqueous extract (COFAE) C. compare it with that turmerones (volatile oil), bioactive components are proven potential. against inflammation evaluated xylene-induced ear edema, cotton pellet granuloma models albino Swiss mice Wistar rats, respectively. results showed...
// Anjan Thakurta 1 , William E. Pierceall Michael D. Amatangelo Erin Flynt and Amit Agarwal 2 Translational Medicine, Bristol Myers Squibb, Summit, NJ, USA Global Medical Affairs, Correspondence to: Thakurta, email: anjan.thakurta@bms.com Keywords: multiple myeloma; combinations; immunomodulatory agents; apoptosis; protein degradation Received: March 19, 2021 Accepted: May 13, Published: July 20, Copyright: © et al. This is an open access article distributed under the terms of Creative...
A randomized, double-blind, placebo-controlled study was conducted to evaluate the efficacy of GutGard, an extract Glycyrrhiza glabra, in patients with functional dyspepsia. The primary outcome variables were change severity symptoms and global assessment efficacy. quality life evaluated as a secondary measure. received either placebo or GutGard (75 mg twice daily) for 30 days. Efficacy terms (as measured by 7-point Likert scale), efficacy, using short-form Nepean Dyspepsia Index. In...
Abstract Background and Objectives Chronic pancreatitis (CP) is a fibroinflammatory disease causing functional injury. Abdominal pain the predominant symptom negatively impacting quality of life. The Comprehensive Pain Assessment Tool (COMPAT-SF) questionnaire, designed validated to assess in CP, was previously only available English Danish. Given high prevalence CP India, translating validating COMPAT-SF into different languages becomes crucial. Methods underwent translation three Indian...
Context: Phyllanthus (Euphorbiaceae) species are traditionally well-known for their medicinal properties including hepatoprotective activity.Objective: The study assessed the and antioxidant activities of 11 species, P. amarus Schumach., urinaria L., debilis Klein ex Willd, tenellus Roxb., virgatus G. Forst., maderaspatensis reticulatus Poir., polyphyllus Willd., emblica indofischerii Bennet. acidus (L.) Skeels.Materials methods: dried leaves stems each plant were extracted in methanol...
Diverse high energy diets have been utilized to precipitate obesity and related metabolic disorders in rodent models, though the dietary intervention has not absolutely standardized. The present study established usage of a customized semipurified normal control diet (NCD) fat (HFD), for research studies on diet-induced albino rats. Male Wistar rats were fed with pellet (NPD) or NCDs I, II, III HFDs 12 weeks parameters, namely, body weight, visceral adiposity, serum triglycerides,...
N. nucifera is one among the important medicinal plants assessed for its antiobesity action in various preclinical models. The present study was aimed at investigating effect of methanol and successive water extracts petals by studying on adipogenesis, adipolysis, lipase, serotonin (5-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
The present study investigated anti‐stress potential of Ocimum sanctum in chronic variable stress (CVS) paradigm. Further, the possible mechanism was explored vitro using cell and cell‐free assays. Rats were administered O. followed by CVS regimen for a period 16 days. On days 4, 8, 12, 16, body weight immobility time forced swim test measured. In addition, inhibitory effect ursolic acid on cortisol release CRHR1 receptor activity studied cell‐based assays, while effects 11β‐hydroxysteroid...