A5070122777- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Analytical Chemistry and Chromatography
- Enzyme Production and Characterization
- Amino Acid Enzymes and Metabolism
- Nanoparticles: synthesis and applications
- Enzyme-mediated dye degradation
- Biofuel production and bioconversion
- Microbial Metabolites in Food Biotechnology
- Electrochemical sensors and biosensors
- Cancer therapeutics and mechanisms
- Protein Hydrolysis and Bioactive Peptides
- Nanoplatforms for cancer theranostics
- Synthesis and biological activity
- Carbohydrate Chemistry and Synthesis
- Phytase and its Applications
- Biochemical and Molecular Research
- Protein purification and stability
- Photodynamic Therapy Research Studies
- Pancreatic function and diabetes
- Innovative Microfluidic and Catalytic Techniques Innovation
- Bioactive Compounds and Antitumor Agents
- Viral Infectious Diseases and Gene Expression in Insects
- Microbial Metabolism and Applications
- Porphyrin and Phthalocyanine Chemistry
National Institute of Pharmaceutical Education and Research
2013-2025
National Institute of Pharmaceutical Education and Research
2004-2025
National Institute of Pharmaceutical Education and Research
2014-2024
All India Institute of Medical Sciences Rishikesh
2023
Amity University
2023
Indian Institute of Science Education and Research Mohali
2015-2016
Pharmaceutical Biotechnology (Czechia)
2015
Institute of Microbial Technology
1993-2003
University of Waterloo
1993-1996
University of Burdwan
1984-1987
On the basis of structures known topoisomerase II catalytic inhibitors and initial molecular docking studies, bicyclic N-fused aminoimidazoles were predicted as potential inihibitors. They synthesized by multicomponent reactions evaluated against human IIα (hTopoIIα) in decatenation, relaxation, cleavage complex, DNA intercalation vitro assays. Among 31 compounds eight different scaffolds, it was found that imidazopyridine, imidazopyrazole, imidazopyrazine with suitable substituents...
A simple and efficient eco-friendly approach for the biosynthesis of stable, monodisperse silver nanoparticles (AgNPs) using Rhododendron dauricum flower extract is described.Different reaction parameters (concentration plant extract, substrate concentration, pH, temperature time)were optimized to synthesize AgNPs with controlled properties.AgNPs were characterized in terms synthesis, size distribution (PDI 0.25), capping functionalities (phenolic compounds) microscopic evaluation by...
The 2-(2-arylphenyl)benzoxazole moiety has been found to be a new and selective ligand for the enzyme cyclooxygenase-2 (COX-2). 2-(2-arylphenyl)benzoxazoles 3a-m have synthesized by Suzuki reaction of 2-(2-bromophenyl)benzoxazole. Further synthetic manipulation 3f 3i led 3o 3n, respectively. compounds 3g, selectively inhibited COX-2 with selectivity index 3n much better than that NSAID celecoxib. in vivo anti-inflammatory potency 3g is comparable celecoxib nonselective diclofenac at two...
Abstract Lipase‐catalyzed organic reactions have widely been practiced in the past three decades. In addition to its wide acceptance conventional such as hydrolysis, transesterification, and enantiopure synthesis (kinetic resolution dynamic kinetic resolution) several reports on catalytic promiscuity of lipases also published. The concept promiscuity, where lipase catalyzes beyond natural function, has perceived a useful phenomenon which can enhance utility biocatalyst. Many Aldol...