A5060305708- Medical Imaging Techniques and Applications
- Epilepsy research and treatment
- Autoimmune Neurological Disorders and Treatments
- Brain Metastases and Treatment
- Hematological disorders and diagnostics
- Lymphoma Diagnosis and Treatment
- Histiocytic Disorders and Treatments
- Eosinophilic Disorders and Syndromes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Glioma Diagnosis and Treatment
- Lysosomal Storage Disorders Research
- Parvovirus B19 Infection Studies
- Acute Ischemic Stroke Management
- CNS Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Neuroscience and Neuropharmacology Research
- Cardiac tumors and thrombi
- Sarcoma Diagnosis and Treatment
- Vagus Nerve Stimulation Research
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Vascular Tumors and Angiosarcomas
- Radiomics and Machine Learning in Medical Imaging
- Sarcoidosis and Beryllium Toxicity Research
- Breast Lesions and Carcinomas
Institut d'Investigació Biomédica de Bellvitge
2010-2025
Bellvitge University Hospital
2012-2025
Duran i Reynals Hospital
2024
Institut Català d'Oncologia
2024
The aim of this study was to assess the physical performance a new PET/CT system, Discovery IQ with 5-ring detector blocks. <b>Methods:</b> Performance measured using National Electrical Manufacturers Association NU2-2012 methodology. Image quality extended by accounting for different acquisition parameters (lesion-to-background ratios [8:1, 4:1, and 2:1] times) reconstruction algorithms (VUE-point HD [VPHD], VPHD point-spread-function modeling [VPHD-S], Q.Clear). Tomographic also assessed...
Background: Antibodies to glutamic acid decarboxylase (GAD ab) have been found in patients with limbic encephalitis (LE) and chronic pharmacoresistant focal epilepsy (FE). The objectives of the study were to: (1) analyze clinical neuroimaging course FE+GAD ab, (2) compare these characteristics a control group, (3) describe most affected cerebral areas structural functional imaging. Methods: Patients FE + high titers GAD ab follow-up at least 5 years selected. Titers serum exceeding 2,000...
Background Musicogenic reflex seizures (MRS) are a rare form of described in patients with temporal lobe epilepsy (TLE), mainly unknown etiology. Epilepsy antibodies against glutamic acid decarboxylase (GAD-ab) is autoimmune for which no specific semiology has been described. Aim the study To retrospectively review incidence MRS general epileptic population and series GAD-ab to describe its clinical paraclinical characteristics. Methods Patients recorded between January 2010 2016 Database...
Abstract Background Niemann–Pick disease type C (NP-C) is a rare genetic lysosomal lipid storage disorder characterized by progressive neurological impairment. Early diagnosis critical for initiating treatment with miglustat, which can decelerate progression. In this study, we evaluated cohort of 22 NP-C patients who underwent MRI, [ 18 F]FDG PET, and clinical assessment at baseline. We performed cross-sectional longitudinal imaging study evaluating the role PET as an adjunct diagnostic tool...
TPS6125 Background: The prognosis of locally-advanced head and neck squamous cell carcinoma (LA-HNSCC) remains poor, with a 60% 5-year overall survival (OS) rate despite curative-intent therapies. Treatment intensification strategies antiPD-(L)1 agents given concurrently to (chemo)radiotherapy (CRT) have failed improve survival. New radiosensitizing such as PARP inhibitors shown encouraging results in early studies, are special interest cisplatin-unfit patients (pts) (Moutafi et al. 2021)....
Objective The aim of the study was to determine evolution patients with internal mammary chain (IMC) drainage whether IMC-sentinel lymph node (IMC-SLN) biopsied or not, as well clinical implications biopsy IMC-SLN (IMC-SLNB) in breast cancer and IMC lymphoscintigraphy. Methods Eighty-two out 914 included a prospective database sentinel (9%) showed were study. Two groups established depending on removal: group A (IMC-SLN removed): 44 patients, mean age 48.8 years, follow-up, 35.8 months....
Niemann-Pick disease Type C (NPC) is a genetic, incurable, neurodegenerative disorder. This orphan most frequently caused by mutations in the NPC1 protein, resulting intralysossomal cholesterol accumulation. found neuronal cell bodies, axon terminals and synaptosomes, suggesting it plays role lysosomal degradation pathway synaptic transmission. Neuronal function especially vulnerable to deficiency changes seem key element development. Currently, Miglustat (Zavesca®) only approved treatment...
Medullary thyroid carcinoma (MTC) is a rare malignancy. Location of residual, recurrent, or metastatic disease crucial to treatment management and outcome. We aimed evaluate the use F-FDG PET/CT in localizing MTC foci patients with biochemical relapse.This retrospective cohort study. Review 51 FDG studies 45 referred restage due increased calcitonin (Ctn) carcinoembryonic antigen (CEA) values at follow-up. diagnostic accuracy was determined through patient-based analysis, using histology as...
Eating-induced seizures (EIS) are a rare form of reflex seizures. The objective this study was to report series cases EIS involving patients admitted our epilepsy unit, and analyze the clinical characteristics, etiology, treatment response type infrequent seizure.We performed single-center retrospective analysis all consecutive diagnosed with eating-induced between 2008 2020.We included eight (six women) mean age 54.75 years (range: 40-79), at onset 30.75 9-58 years). were triggered during...
Drug resistant epilepsy (DRE) has been associated with a high incidence of psychotic disorders. Patients can develop psychosis after starting new antiseizure medication, undergoing resective surgery, or implantation vagus nerve stimulation (VNS) system. The aim this study was to investigate the modulation effect VNS on episodes in DRE patients pre-existing history periictal (PPE). We retrospectively report outcome four from single tertiary center PPE prior implantation. None implanted...
Glutamic acid decarboxylase antibodies (GAD-Ab) are sometimes associated with chronic drug-resistant focal epilepsy. Clinically, it may manifest as mesial temporal lobe epilepsy (mTLE), GAD-Ab patients difficult to distinguish. Therefore, the aim of this study is compare brain metabolism mTLE and high serum titers (>2000 UI/ml) those hippocampal sclerosis (HS) confirmed GAD-ab negativity.Images from PET studies were normalized an SPM 12 template. Voxel voxel comparisons made using a...