The increasing use of the common marmoset (Callithrix jacchus) in research makes it important to diagnose spontaneous disease that may confound experimental studies. Bone and gastrointestinal are two major causes morbidity mortality captive marmosets, but currently no effective antemortem tests available identify affected animals prior terminal stage disease. In this study we propose bone associated entities marmosets aim establish efficacy several economical identifying predicting Tissues...

A 2-d-old Warmblood colt was submitted for autopsy with a spectrum of bilateral ocular abnormalities. At postmortem examination, constellation lesions within the anterior segment included retention ectodermal elements, compatible choristoma. Ocular choristomas can be localized to different intraocular structures and are rare in equids. The morphologic features our case were suggestive abnormal corneal differentiation.

It has recently been reported that relatively short-term inhibition of vascular endothelial growth factor (VEGF) signaling can cause photoreceptor cell death, a potentially clinically important finding since VEGF blockade become an modality treatment ocular neovascularization and macular edema. However, in set studies which we achieved extended complete blockage VEGF-induced leakage through retinal expression binding protein, did not observe any toxicity to neurons. To follow-up on these...

The common marmoset ( Callithrix jacchus) is a New World primate that used in biomedical research due to its small size and relative ease of handling compared with larger primates. Although bone disease marmosets well recognized, there are very few detailed descriptions the literature cover range lesions seen these animals. For all animals model human disease, it important be aware background may affect interpretation study findings. This retrospective details diseases encountered breeding...

Purpose: To perform a comprehensive clinical, diagnostic, and imaging characterization of the ocular surface in West Highland White Terriers (WHWTs) diagnosed with aqueous deficient dry eye (ADDE) disease. Methods: Six ADDE-affected 13 ADDE-unaffected WHWT dogs were enrolled underwent clinical assessment disease scoring, tear osmolarity, phenol red thread test, Schirmer film breakup time, fluorescein staining, Rose bengal lissamine green vital dye meibometry, corneal esthesiometry,...

Abstract Purpose To perform selected ophthalmic diagnostic tests in healthy capuchin monkeys ( Cebus apella ) with the aim of establishing normal physiological reference values for this species. Methods A total 15 healthy, were used to test most parameters investigation. Five evaluation conjunctival flora. Ages varied from 6 20 years age. Selected ocular performed including Schirmer tear (STT), tonometry using an applanation tonometer (Tonopen ® ), central corneal thickness (CCT) ultrasonic...

Portuguese Water Dog breeders and veterinary ophthalmologists recognize microphthalmia with multiple congenital ocular anomalies. Fifteen puppies (<8 weeks of age; 8 females, 7 males) 1 adult (5 years old; castrated male) were examined. The 2 most common abnormalities (31/32 eyes; 97%) lens abnormality (congenital cataract or aphakia; 32/32 100%). Other histologic lesions included lack both a ciliary cleft trabecular meshwork (15/32 47%) abnormal relationship anterior segment structures...

Abstract Objective s To identify canine breeds at risk for ocular melanosis and to compare the clinical histologic features between affected Cairn Terriers (CTs) non‐Cairn (NCTs). Design Relative (RR) analysis retrospective cohort study of dogs histologically diagnosed with melanosis. Procedures The COPLOW archive was searched globe submissions Six hundred fifty globes were included, RR performed at‐risk NCT breeds. A 360 CT from 2013 2023 included in study. Clinical data collected...

Summary Angiomatosis refers to a vascular tumour consisting of several vascular, blood‐filled cavities with lining well‐differentiated endothelial cells. This condition is seen in very young cattle as malformative process and has been documented other animals well. In horses, this disease only rarely described, no reported lesions being found within the equine orbit. report details clinical findings, surgical exploration, histopathology, long‐term follow‐up an aged horse orbital angiomatosis.

Purpose: The aim of this study was to investigate the effects prostaglandin analogs on blood flow in ophthalmic artery clinically healthy rabbits. Methods: Fifty-five New Zealand white rabbits were divided into six groups, and left eyes treated for four weeks with preservative benzalkonium chloride (BAK) only or a topical formulation different (bimatoprost BAK, tafluprost BAK-free, travoprost POLYQUAD, latanoprost BAK). Color Doppler imaging performed before after treatments. mean values...

Spontaneously occurring ocular neoplasia is rarely reported in rabbits. This case series presents four cases of rabbits diagnosed with iridociliary tumors, which have not been previously this species. Major pathological findings include epithelial tumors affecting the anterior uvea variable pigmentation and basement membrane formation. Follow-up information was only available for two cases, but neither showed evidence metastasis, suggesting that prognosis these rabbits, as other species, may...

Abstract An eleven‐year‐old, female spayed Boxer dog was diagnosed with a uveal schwannoma (formerly known as the spindle cell tumor of blue‐eyed or SCTBED ) despite having uniformly brown iris. The patient presented to emergency for ocular discomfort, and right globe subsequently enucleated due glaucoma submitted histopathology. Upon histopathologic evaluation, confirmed immunohistochemical staining. Complete metastatic evaluation 1 6 months after initial presentation did not reveal...

This report aims to describe a case of tumor-like lymphoplasmacytic conjunctivitis in 7-year-old spayed-female Pomeranian. On complete ophthalmic examination, mass with papillary projections was noted on the bulbar surface right third eyelid. Debulking performed while preserving as much eyelid possible. histopathological diagnosed mild epithelial hyperplasia. Although slight regrowth 3 weeks after surgery, intralesional injection triamcinolone acetonide led its disappearance. There no...

Purpose: To retrospectively evaluate and describe the relationship between use of topical corticosteroids development crystalline corneal opacities (steroid keratopathy) in a colony research Beagles Beagle-derived dogs. Methods: Medical records 73 purpose-bred dogs were reviewed from June 2012 to May 2021. All treated with ophthalmic for at least 21 days. In addition regular examination, some also had systemic lipid profile (n = 6) performed work up further characterize opacities. Globes 3...

Abstract A 13‐year‐old, domestic shorthair cat presented for evaluation of left‐sided exophthalmos, epiphora and third eyelid elevation approximately 4‐month duration. Based on ophthalmic exam findings, a retrobulbar mass was suspected. Computed tomography the head revealed fluid to soft‐tissue, non‐contrast‐enhancing caudoventral left globe. these abscess considered most likely differential, while neoplastic could not be completely excluded. The globe were surgically excised via modified...

Abstract Objective To describe the case of a 12‐year‐old male African lion ( Panthera leo ) presented with ocular discharge, corneal edema, and buphthalmos right eye. Procedures Ocular ultrasonography showed an intraocular mass involving iris ciliary body. Enucleation was performed. Results Subsequent histopathological analysis revealed pleomorphic pigmented neoplastic cell population infiltrating, expanding effacing body occupying cleft. The immunohistochemical features were consistent...

Abstract Purpose To describe the clinical and histopathologic features secondary to ocular periocular snakebites in dogs requiring enucleation. Methods Retrospective review of patients with recorded snakebite envenomation from archives Comparative Ocular Pathology Laboratory Wisconsin (COPLOW) Texas A&M Veterinary Medical Teaching Hospital (1997‐2017). The cases included this study required witnessed dog by owner, signs supportive or envenomation, and/or lesions compatible snakebites....