A5029410184- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Tendon Structure and Treatment
- Virus-based gene therapy research
- Immunotherapy and Immune Responses
- Animal Virus Infections Studies
- Pluripotent Stem Cells Research
- Cancer Immunotherapy and Biomarkers
- Mesenchymal stem cell research
- Viral Infections and Vectors
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Mycology
- Virology and Viral Diseases
- Mycobacterium research and diagnosis
- CAR-T cell therapy research
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Foot and Ankle Surgery
- Whipple's Disease and Interleukins
- Tissue Engineering and Regenerative Medicine
- Viral Infections and Immunology Research
- COVID-19 and Mental Health
- Biochemical and Structural Characterization
- Cancer Mechanisms and Therapy
- Melanoma and MAPK Pathways
Universiti Tunku Abdul Rahman
2015-2025
University of Selangor
2021-2022
Universiti Putra Malaysia
2005-2013
Johns Hopkins University
1998
Johns Hopkins Hospital
1998
In patients with head and neck squamous cell carcinoma (HNSCC), a (SCC) in the lung represents either another primary tumor or metastasis. This distinction greatly influences patient prognosis could guide treatment strategies, but nature of solitary nodule is often difficult to discern by use standard clinical histologic parameters. Comparison genetic alterations tumors resolve this dilemma.We compared paired from 16 HNSCC SCC for loss (i.e., deletion) loci on chromosomal arms 3p 9p. Losses...
This study aims to assess the incidence rate of Pteropine orthreovirus (PRV) infection in patients with acute upper respiratory tract (URTI) a suburban setting Malaysia, where bats are known be present neighborhood. Using molecular detection PRVs directly from oropharyngeal swabs, our demonstrates that PRV is among one common causative agents URTI cough and sore throat as commonest presenting clinical features. Phylogenetic analysis on partial major outer inner capsid proteins shows these...
Molecular alterations in KRAS, BRAF, PIK3CA, and PTEN have been implicated designing targeted therapy for colorectal cancer (CRC). The present study aimed to determine the status of these molecular Malaysian CRCs as such data are not available literature. We investigated mutations PTEN, gene amplification protein expression phosphatidylinositol 3-kinase (PI3K) catalytic subunit (p110α) by direct DNA sequencing, quantitative real-time PCR, immunohistochemistry, respectively, 49 CRC samples....
Interleukin (IL)-17A and IL-17F are inflammatory cytokines mainly produced by T helper 17 cells. IL-17A is known to be protumorigenic while has a protective role in cancer. A number of studies have been conducted determine the association between polymorphisms IL-17AG197A (rs2275913) IL-17FA7488G (rs763780) risk cancers. No yet genotype polymorphism colorectal cancer (CRC).To assess with CRC risk.We performed genotyping polymerase chain reaction-restriction fragment length method on blood...
Background In Malaysia the COVID-19 disease (COVID-19) has continued to escalate since its first detection in late January 2020, despite widespread implementation of control measures. This study aims determine knowledge, perception and behaviors with respect midst third wave infection. Methods A cross-sectional was carried out among staffs students Universiti Tunku Abdul Rahman (UTAR). The survey consists basic sociodemographic information, 22 items on knowledge COVID-19, 3 perceived...
Pteropine orthoreovirus (PRV) is an emerging zoonotic respiratory virus that can be transmitted from bats to humans. In Malaysia, aside PRV2P (Pulau virus) being isolated Pteropus hypomelanus sampled in Tioman Island, PRV3M (Melaka virus), PRV4K (Kampar and PRV7S (Sikamat were all samples of patients who reported having a disease spectrum acute distress influenza-like illness sometimes even with enteric symptoms such as diarrhea abdominal pain. Screening sera collected human volunteers on...
Background: Oncolytic properties had been demonstrated in Mammalian Orthoreovirus (MRV) and Avian Orthorevirus (ARV). Besides MRV ARV, Pteropine (PRV) is also categorized under the genus Orthoreovirus. PRV7S (Sikamat virus) an orthoreovirus isolated Malaysia. Present study aims to investigate oncolytic effects of on ranges nasopharyngeal carcinoma (NPC) cells through apoptosis comparison MRV3. Methods: Non-cancerous (NCNP) NPC were infected by The proliferation inhibition apoptotic activity...
The giant amoebal viruses of Mimivirus and Marseillevirus are large DNA have been documented in water, soil, sewage samples. trend discovering these has increasing throughout Asia with Japan, India, Saudi Arabia being the latest countries to document presence viruses. To date, there no reports isolated South East Asia.In this study, we aim discover from soil samples an aboriginal village (Serendah village) Peninsular -Malaysia.We successfully detected both Mimivirus-like Marseillevirus-like...
This study aims to isolate clinical adenovirus among hospitalized children in Seremban, Malaysia. After that, determination of the serotype and genetic relatedness isolated through phylogenetic analysis with published database human from GenBank will be carried out. 26 HAdV-positive retrospective respiratory specimens were collected pediatric patients distress at Pediatric Department Hospital Tuanku Jaafar HAdV was A549 cell culture, sequenced analysed for typing. Based on hexon, penton, DNA...
<title>Abstract</title> This study investigated the extrapulmonary pathogenesis of a novel <italic>Mycobacteroides abscessus subsp. massiliense</italic> strain in young adult, manifesting as chronic cutaneous infection. Epidemiological investigation proposed pathogen transmission via contaminated Java apple fruit, likely facilitated by tree shrews. The strain, identified through next-generation sequencing, demonstrated resistance to 76.7% tested antibiotics, and potential heteroresistance...
Abstract This study investigated the extrapulmonary pathogenesis of a novel Mycobacteroides abscessus subsp. massiliense strain in young adult, manifesting as chronic cutaneous infection. Epidemiological investigation proposed pathogen transmission via contaminated Java apple fruit, likely facilitated by tree shrews. The strain, identified through next-generation sequencing, demonstrated resistance to 76.7% tested antibiotics, and potential heteroresistance among M. subpopulations were...
Ankle sprain has a great effect on morbidity and complications of chronic diseases. Experts have come to consensus where ankle can be managed by rest, ice, compression elevation, non-steroidal anti-inflammatory drugs, immobilisation, functional support such as the use an brace, exercise, surgery other therapies that include physiotherapy modalities acupuncture. However, time required for healing is still relatively long in addition post-operative complications. Because challenges setbacks...