A5088274896- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Electroconvulsive Therapy Studies
- Sleep and related disorders
- Advanced MRI Techniques and Applications
- Treatment of Major Depression
- Long-Term Effects of COVID-19
- Psychosomatic Disorders and Their Treatments
- Attachment and Relationship Dynamics
- Mental Health Research Topics
- Maternal Mental Health During Pregnancy and Postpartum
- Sleep and Wakefulness Research
- Hallucinations in medical conditions
University of Bern
2021-2025
University Hospital of Bern
2021-2025
Structural and functional alterations of the anterior cingulate cortex (ACC) have been related to emotional, cognitive behavioral domains major depressive disorder. In this study, we investigate cortical thickness rostral caudal ACC. addition, explore white matter microstructure cingulum bundle (CB), a pathway connecting multiple segments We hypothesized reduced CB in MDD, particular melancholic subtype. expect an association between depression severity microstructure. Fifty-four patients...
Abstract Electroconvulsive therapy (ECT) is a highly effective treatment for depression. Previous studies point to ECT-induced volume increase in the hippocampi and amygdalae, cortical thickness. However, it unclear if these neuroplastic changes are associated with response. This observational study aimed address this research question by comparing neuroplasticity between patients depression receiving ECT that respond as usual (TAU-responders). Twenty ECT-patients (16 major depressive...
Sleep disturbances are common in depression, but their neurobiological correlates poorly understood. Recent evidence suggests links between insula dysfunction and sleep dysregulation. This study aimed to explore the association of quality structural functional characteristics major depressive disorder (MDD). We included 47 patients with MDD 15 healthy controls (HC) matched for age sex. was assessed Pittsburgh Quality Index (PSQI). Patients were classified into two subgroups poor (PAT-PS,...
Electroconvulsive therapy (ECT) is a highly efficient treatment for depression. Previous studies repeatedly reported an ECT-induced volume increase in the hippocampi. We assume that this also affects extended hippocampal networks. This study aims to investigate structural and functional interplay between hippocampi, pathways core regions of default mode network (DMN). Twenty patients with current depressive episode receiving ECT-treatment twenty age sex matched healthy controls (HC) were...
Insecure attachment style (anxious and avoidant) predisposes to the development of depression has been linked hippocampal alterations in healthy individuals. However, it is unclear if there are hippocampus parahippocampal cingulum (PHC) patients with depression. Forty-eight major depressive disorder 18 controls underwent MP2RAGE diffusion-weighted magnetic resonance imaging. Attachment characteristics were assessed revised adult scale. Patients classified into subgroups low (anxious: n = 27;...
Numerous studies show that electroconvulsive therapy (ECT) induces hippocampal neuroplasticity, but findings are inconsistent regarding its clinical relevance. This study aims to investigate ECT-induced plasticity of anterior and posterior hippocampi using mathematical complexity measures in neuroimaging, namely Higuchi's fractal dimension (HFD) for fMRI time series the cortical morphology (FD-CM). Furthermore, we explore potential these predict ECT treatment response.
Abstract Background Numerous studies show that electroconvulsive therapy (ECT) induces hippocampal neuroplasticity, but findings are inconsistent regarding its clinical relevance. This study aims to investigate ECT-induced plasticity of anterior and posterior hippocampi using mathematical complexity measures in neuroimaging, namely Higuchi’s fractal dimension (HFD) for fMRI time series the cortical morphology (FD-CM). Furthermore, we explore potential these predict ECT treatment response....