Melvyn Rubenfire

ORCID: 0000-0002-0290-7154
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cardiac Health and Mental Health
  • Pulmonary Hypertension Research and Treatments
  • Heart Failure Treatment and Management
  • Cardiac Arrhythmias and Treatments
  • Cardiac Imaging and Diagnostics
  • Lipoproteins and Cardiovascular Health
  • Cardiovascular Function and Risk Factors
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular and exercise physiology
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Heart Rate Variability and Autonomic Control
  • Cardiovascular Issues in Pregnancy
  • Cardiac Valve Diseases and Treatments
  • Cardiac Arrest and Resuscitation
  • Cardiovascular Effects of Exercise
  • Atrial Fibrillation Management and Outcomes
  • Congenital Heart Disease Studies
  • Cardiovascular Health and Risk Factors
  • Cardiac pacing and defibrillation studies
  • Cardiovascular Health and Disease Prevention
  • Blood Pressure and Hypertension Studies
  • Acute Myocardial Infarction Research
  • Cardiac Structural Anomalies and Repair
  • ECG Monitoring and Analysis
  • Health Promotion and Cardiovascular Prevention

Michigan Medicine
2015-2024

University of Michigan–Ann Arbor
2015-2024

Michigan United
2014-2024

Rogers (United States)
2020

University Health System
2016-2020

Löwenstein Medical (Germany)
2020

Eastern Michigan University
2020

Morishita Jintan (Japan)
2020

FishBase Information and Research Group
2020

McGowan Institute for Regenerative Medicine
2019

Eighty-seven patients with cardiogenic shock were treated the intra-aortic counterpulsating balloon in 10 institutions according to a common protocol. Clinical and physiologic responses favorable most patients. Heart rate fell from 110 ± 24 (mean S.D.) 103 21 beats per minute, systolic arterial pressure ("afterload") 76 22 57 17 mm Hg, diastolic increased 53 12 83 19 mean did not change. Cardiac output 500 ml decrease lactate production or increase extraction by myocardium occurred 18 of...

10.1056/nejm197305102881901 article EN New England Journal of Medicine 1973-05-10

We report clinical experience with the coronary vasodilator nifedipine in 127 patients symptoms of myocardial ischemia associated electrocardiographic or angiographic evidence, both, coronary-artery spasm. In majority conventional antianginal therapy including nitrates and beta-adrenergic blockers failed, one third at least episode ventricular tachycardia developed during an attack angina. Nifedipine (40 to 160 mg every 24 hours) significantly reduced mean weekly rate anginal attacks from 16...

10.1056/nejm198006053022301 article EN New England Journal of Medicine 1980-06-05

The objective of this study was to compare coronary flow reserve (CFR) as a measure vascular integrity in asymptomatic middle-aged men with family history artery disease (CAD) and high-risk lipid profile without risk factors for CAD using positron emission tomography (PET). Previous studies suggested that the assessment CFR is sensitive means detect abnormalities before angiographic appearance CAD. N-13 ammonia PET scanning allows noninvasive evaluation regional global myocardial blood...

10.1161/01.cir.90.2.808 article EN Circulation 1994-08-01

There are no reliable predictors of mortality in primary pulmonary hypertension (PPH). This study assessed whether exercise oxygen desaturation and distance achieved during a six-minute walk associated with moderately symptomatic patients PPH. Thirty-four PPH underwent pretreatment test, an invasive haemodynamic assessment vasodilator reserve, to select the best treatment option (epoprostenol 27 nifedipine 7). Median follow-up was 26 months (12 for nonsurvivors 26%), median survival, >46...

10.1183/09031936.01.17406470 article EN European Respiratory Journal 2001-04-01

Pulmonary hypertension (PH) is a fatal disease. Although the prognosis of pulmonary arterial (PAH) has improved with targeted therapies, outcome dependent on early detection and an accurate diagnosis.To determine accuracy PH diagnoses in patients referred to centers frequency PAH-specific medication use despite uncertain or incorrect diagnosis.Multicenter, descriptive, cross-sectional study. During 10-month period 2010 2011, data newly were collected entered into secure Internet...

10.1001/jamainternmed.2013.319 article EN JAMA Internal Medicine 2013-04-08

The goal of this research was to evaluate the personal health behaviors physicians in training and attending association with patient-related lifestyle counseling. Physicians at a major teaching hospital were surveyed regarding their behavior, perceived confidence, frequency counseling patients behaviors. One hundred eighty-three total responses received. Trainees more likely consume fast food less fruits vegetables than attendings. Attending exercise 4 or days per week 150 minutes week....

10.1111/j.1751-7141.2010.00079.x article EN Preventive Cardiology 2010-08-16

Patients with pulmonary arterial hypertension (PAH) often die from right heart failure or sudden cardiac death. Cardiopulmonary resuscitation (CPR) may be instituted in these patients but there are no data the medical literature about outcome of CPR this group patients. We conducted a retrospective multicenter international study on frequency and results PAH. A total 3,130 PAH were treated between 1997 2000 17 referral centers Europe United States. During period, 513 had circulatory arrest...

10.1164/ajrccm.165.3.200109-0130c article EN American Journal of Respiratory and Critical Care Medicine 2002-02-01

Retrospective and prospective analyses of chest radiographs patients following coronary artery bypass surgery were undertaken. Left lower lobe pulmonary infiltrate and/or atelectasis developed in 13 40 (32.5%) who operated upon without topical cooling the heart with ice, 77 122 (63.1%) one group 34 (85.0%) another ice. This difference was highly significant (p less than 0.001). Of whom left abnormality developed, 69.2% had paralysis or paresis hemidiaphragm. It is evident that application...

10.1148/radiology.142.1.6975951 article EN Radiology 1982-01-01

10.1016/j.amjcard.2012.04.062 article EN The American Journal of Cardiology 2012-06-01

Validation of associations for SNPs in RAC2, NCF4 and SLC28A3, identification a novel association with TOP2B SNP screening 23 putatively relevant to anthracycline-induced cardiotoxicity.A total 166 breast cancer patients treated doxorubicin underwent echocardiogram, including 19 cases systolic dysfunction (ejection fraction <55%) 147 controls. Four high priority were tested the primary analysis, appropriate statistical correction, additional screened an uncorrected secondary...

10.2217/pgs.15.162 article EN Pharmacogenomics 2016-01-22
Coming Soon ...