A5038752515- Wound Healing and Treatments
- Cytokine Signaling Pathways and Interactions
- Virus-based gene therapy research
- Advanced Proteomics Techniques and Applications
- Pressure Ulcer Prevention and Management
- Education and Critical Thinking Development
- Neuropeptides and Animal Physiology
- Pluripotent Stem Cells Research
- Bacteriophages and microbial interactions
- Synthesis and Characterization of Heterocyclic Compounds
- Monoclonal and Polyclonal Antibodies Research
- Pancreatic function and diabetes
- Extracellular vesicles in disease
- Education and Islamic Studies
- Pain Mechanisms and Treatments
- Pediatric Pain Management Techniques
- interferon and immune responses
- Enzyme Catalysis and Immobilization
- Educational Practices and Challenges
- Vibrio bacteria research studies
- Spinal Cord Injury Research
- Veterinary Pharmacology and Anesthesia
- Diagnosis and Treatment of Venous Diseases
- Microbial Metabolic Engineering and Bioproduction
- Mesenchymal stem cell research
National Institute of Genetic Engineering and Biotechnology
2012-2023
Malek Ashtar University of Technology
2017-2019
Baqiyatallah University of Medical Sciences
2019
Abstract Pancreatic duodenum homeobox protein‐1 (PDX1) is a master regulatory gene in pancreatic development. Reprogramming of mesenchymal stem cells (MSCs) promising tool for producing insulin‐producing cells. In this study, lentivirus harboring PDX1 (LV‐PDX1) has been used persistence expression MSCs. The objective study was to evaluate the potential introduce into MSCs produce insulin‐secreting and apply it treatment hyperglycemia diabetic rats. were isolated from rat bone marrow,...
Objective: This study aimed at comparing the descriptive assessment in terms of critical and creative thinking sixth grade students public private schools district four Karaj. is a research which done causal-comparative method. Methodology: The population consisted all (girls boys) primary schools. According to information, total number was 8529 people, 7788 them were selected among school 741 students. sample size 368 determined by using Morgan table, 330 samples belonged 38 Stratified...
Background: Human IFN-α is a family of structurally related proteins that exhibit wide range antiproliferative and antiviral activities. IFNs bind to specific cell receptor as the IFN-α/β (IFNAR) compose IFNAR1 IFNAR2 chains. Interferon’s affinity for chains changes type its activity. Objective: To understand structural basis these different activities, some important amino acid residues in this study binding region interferon were replaced more effective ones. Method: In order suggestion...
Traumatic brain injury (TBI) is the leading cause of death, disability, and mental health disorders. A wide range bioactive lipids, cytokines, chemokines drives inflammatory response. This study aimed to assess efficacy buprenorphine on moderate Trauma Brain Injury (mTBI) in rats.In this study, 21 Wistar male rats weighing 230 ± 10 g were included. We trained cases by Morris water navigation task mTBI induced pendulum. Then, treatment with 0.05 mg per kilogram body weight continued from day...
Type I interferons (IFNs) are homologous cytokines that bind to a cell surface receptor and establish signaling pathways motivate immune responses. The purpose of the current study is assess activity novel-engineered IFN-α2b. crystallographic structure IFN-α2b its receptors was acquired from Protein Data Bank. Various amino acid substitutions were designed based on structural properties other biological characteristics residues find most effective IFN affinity advanced activities. mutants...