A5048745358- COVID-19 and healthcare impacts
- Global Public Health Policies and Epidemiology
- Healthcare cost, quality, practices
- Chronic Disease Management Strategies
- Liver Disease and Transplantation
- COVID-19 Clinical Research Studies
- Parathyroid Disorders and Treatments
- Thyroid Disorders and Treatments
- Bone health and treatments
- Drug-Induced Hepatotoxicity and Protection
- Poisoning and overdose treatments
- Genetic Syndromes and Imprinting
- Clinical Laboratory Practices and Quality Control
- Thyroid Cancer Diagnosis and Treatment
- Vitamin D Research Studies
National Health Laboratory Service
2020-2024
Stellenbosch University
2020-2024
Tygerberg Hospital
2020-2024
Abstract Asymptomatic primary hyperparathyroidism (PHPT) is often missed in developing nations due to limited formal healthcare exposure and biochemical screening programs. Many patients are thus only diagnosed once symptomatic. We present a 32-year-old female who developed bony protrusions her jaw during pregnancy, resulting stillbirth. Three months later, dental consultation for worsening toothache, abnormalities were detected. Radiological studies revealed bilateral mandibular radiolucent...
Abstract Objective: The aim of this study was to determine the impact COVID-19 pandemic on test requests for diagnosis and routine care patients with various non-communicable diseases (NCD) across South Africa (SA). Methods: A retrospective audit laboratory received from hospital outpatient departments primary healthcare facilities SA performed. following analytes were studied: glycated hemoglobin (HbA1c), lipids profiles, thyroid-stimulating hormone (TSH), thyroxine (fT4), as well...
Background. Paracetamol is a commonly prescribed drug, and often implicated in pharmaceutical overdoses. Paracetamol-induced hepatotoxicity common cause of acute liver failure many high-income countries, but little known about the factors associated with severity injury poor clinical outcomes among those treated sub-Saharan African settings. Objective. To describe characteristics patients presenting paracetamol poisoning, to identify adults biochemical evidence paracetamol-induced damage at...
Background. Globally, few studies have examined the effect of COVID-19 pandemic on routine patient care and follow-up. Objectives. To evaluate response biochemical test requests received from outpatient departments (OPDs) peripheral clinics serviced by National Health Laboratory Service Chemical Pathology at Tygerberg Hospital, Cape Town, South Africa (SA). Request volumes were used as a measure patients, clinical information was not readily available. Methods. A retrospective audit...
Critical laboratory results are test suggesting a patient is in immediate danger unless treatment administered promptly. There paucity of studies sub-Saharan Africa on clinicians' utility these and affected patients' outcomes. In our resource-limited setting South Africa, we rely telephonic communication to convey critical results.
Non-thyroidal illness syndrome (NTIS) can be defined as the presence of abnormal thyroid function in absence primary dysfunction and is associated with acute illness. Thyroid testing generally not advised critically ill patient. Thyroid-stimulating hormone (TSH) measurement preferred screening test for disease, but results may misleading variable setting critical illness.To describe pattern requests TSH patients admitted to emergency department intensive care units at Tygerberg Hospital,...