- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Sepsis Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Childhood Cancer Survivors' Quality of Life
- Long-Term Effects of COVID-19
- Clinical Nutrition and Gastroenterology
- Family and Patient Care in Intensive Care Units
- Intensive Care Unit Cognitive Disorders
- Renal function and acid-base balance
- Infant Development and Preterm Care
- Electrolyte and hormonal disorders
- Neonatal and Maternal Infections
- Parvovirus B19 Infection Studies
- Pneumonia and Respiratory Infections
- Neuroscience of respiration and sleep
- Hemodynamic Monitoring and Therapy
- Mycobacterium research and diagnosis
- Respiratory viral infections research
- Dialysis and Renal Disease Management
- Hematological disorders and diagnostics
- Obstructive Sleep Apnea Research
- Congenital Diaphragmatic Hernia Studies
- Infectious Diseases and Tuberculosis
KK Women's and Children's Hospital
2017-2024
Riverbank Local Redevelopment Authority
2018
Duke-NUS Medical School
2018
National University of Singapore
2018
Pediatric critical illness exposes family members to stressful experiences that may lead subsequent psychological repercussions.
Abstract: Acute respiratory distress syndrome (ARDS) is a clinical condition that poses significant threat to patients of all age groups. It involves severe inflammation pulmonary tissues and results in hypoxemia. In children, pneumonia remains the major cause paediatric ARDS (PARDS) contrast sepsis adults. this article, we provide narrative review on following specific aspects PARDS over past decade: (I) adoption new neonatal definitions; (II) novel biomarkers risk stratification PARDS;...
Recent research has demonstrated that machine learning (ML) the potential to improve several aspects of medical application for critical illness, including sepsis. This scoping review aims evaluate feasibility probabilistic graphical model (PGM) methods in pediatric sepsis and describe use definition these studies.Literature searches were conducted PubMed, Scopus, Cumulative Index Nursing Allied Health Literature (CINAHL+), Web Sciences from 2000-2023. Keywords included "pediatric",...
With improving mortality rates in pediatric acute respiratory distress syndrome (PARDS), functional outcomes survivors are increasingly important. We aim to describe the change status score (FSS) from baseline discharge and identify risk factors associated with poor outcomes.We examined clinical records of patients PARDS admitted our intensive care unit (PICU) 2009 2016. Our primary outcome was acquired morbidity at PICU hospital (defined by an increase FSS ≥3 points above baseline)....
Background. Tuberculosis (TB) remains a major cause of mortality and morbidity globally. Pediatric patients are more likely to develop severe disease. Abdominal TB is rare manifestation pediatric can present with chronic nonspecific abdominal symptoms. This study examines the clinical profile treatment outcomes. Method. A retrospective admitted tertiary hospital in Singapore over 10 years. Clinical characteristics outcomes were examined. Results. There 3 male female mean age 11.3 Household...
Abstract We report a case of an infant who had presented with fever and acral‐accentuated rash, for which his cerebrospinal fluid returned positive parechovirus. He was treated symptomatically discharged well, no long‐term complications.
Abstract Nutritional practice in children with severe sepsis or septic shock remains poorly described. We aimed to describe nutrition received by and explore the association of nutritional intake clinical outcomes. This study was a retrospective who required pediatric intensive care unit (PICU) admission from 2009 2016. Outcomes were mortality, ventilator-free days (VFDs), PICU-free (IFDs). A total 74 patients identified. Forty-one (55.4%) enteral (EN) only, 6 (8.1%) parental (PN) 15 (20.3%)...
Loh, Sin Wee; Gan, Ming Ying; Ong, Chengsi; Wong, Judith Ju-Ming; Lee, Jan Hau Author Information
Introduction: With improving mortality rates in pediatric acute respiratory distress syndrome (PARDS), functional outcomes survivors are increasingly important. We aim to describe the change status score (FSS) from baseline discharge and identify risk factors associated with poor outcomes. Methods: examined clinical records of patients PARDS admitted our intensive care unit (PICU) 2009 2016. Our primary outcome was acquired morbidity at PICU hospital (defined by an increase FSS ≥3 points...
Introduction: Fluid overload in pediatric acute respiratory distress syndrome (PARDS) has been associated with worse clinical outcomes. The association between fluid and functional status among PARDS survivors remains poorly studied. We hypothesized that is these patients. Methods: This retrospective cohort study included patients (2023 PALICC criteria) Feb2009–Oct2016. primary outcome was change status, assessed by Functional Status Scale (FSS) at hospital admission discharge. An overall of...
Background: We hypothesized that children with viral pneumonia have higher severity of illness and mechanical ventilation (MV) requirement than bacterial pneumonia. aim to compare respiratory support requirements severe cases admitted the pediatric intensive care unit (PICU). Methods: This is a retrospective review patients microbiologically proven PICU in KK Women’s Children’s Hospital, Singapore, from 2010 2014. Demographic, clinical ventilatory data up 14 days admission were extracted...