A5027880433- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Congenital Heart Disease Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Mechanical Circulatory Support Devices
- Respiratory Support and Mechanisms
- Cardiovascular Conditions and Treatments
- Neonatal and fetal brain pathology
- Thermal Regulation in Medicine
- Bacterial Infections and Vaccines
- Hedgehog Signaling Pathway Studies
- Neonatal skin health care
- Genomic variations and chromosomal abnormalities
- Hemodynamic Monitoring and Therapy
- Infant Health and Development
- Pediatric health and respiratory diseases
- Sarcoma Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Soft tissue tumor case studies
- Epilepsy research and treatment
- Bone Tumor Diagnosis and Treatments
- Sepsis Diagnosis and Treatment
- Cancer and Skin Lesions
Saitama Medical University
2014-2024
Social Insurance Saitama Chuo Hospital
2014-2024
Saitama Medical University Hospital
2024
Saitama University
2023
Pediatrics and Genetics
2022
OBJECTIVES: Our aim is to compare the efficacy and safety of high-flow nasal cannula (HFNC) against those continuous positive airway pressure (NCPAP) or intermittent positive-pressure ventilation (NIPPV) after extubation in preterm infants. METHODS: This prospective, randomized, noninferiority trial was conducted 6 tertiary NICUs. Infants born at <34 weeks who needed noninvasive were enrolled. We randomly assigned infants an HFNC group when used NCPAP/NIPPV NCPAP NIPPV used. The...
Abstract High‐flow nasal cannula is a new modality of respiratory support and increasing in popularity despite the lack supporting evidence. We investigated prevalence its use tertiary neonatal units Japan . A paper‐based survey was conducted. The response rate 83%. used 46/80 (58%), which 96% high‐flow without guidelines. It for several indications, including weaning off continuous positive airway pressure post‐extubation support. main perceived benefits included better access to neonate...
Acute encephalopathy has the possibility of sequelae. While early treatment is required to prevent development sequelae, differential diagnosis utmost priority. The aim this study was therefore identify parameters that can facilitate and prediction outcome acute encephalopathy.We reviewed medical charts inpatients from 2005 2011 identified 33 patients with febrile status epilepticus. Subjects were classified into an group (n = 20) a convulsion 13), serum aspartate aminotransferase (AST),...
Abstract Septic shock is associated with impaired vasoregulation, and treatment includes vasoactive drugs. Therefore, evaluation of vasoregulatory change important. The present report describes the successful characterization in response to a drug during septic shock. A male infant born at 23 weeks' gestation developed Severe hypotension developed, colloid fluid dopamine failed increase blood pressure. With continuous measurement skin flow using laser D oppler, noradrenaline was started....
Abstract Background Although indomethacin and ibuprofen are the standard treatments for hemodynamically significant patent ductus arteriosus (hsPDA), they associated with renal impairment gastrointestinal complications. Paracetamol hsPDA closure does not provoke a peripheral vasoconstrictive effect seems to have effects similar those of ibuprofen. We previously reported safety low-dose (7.5 mg/kg) intravenous paracetamol preterm infants hsPDA, who were indomethacin-resistant or...
Abstract Background Several reports have shown the beneficial effects of early or prophylactic surfactant therapy for preterm infants, who often develop respiratory distress syndrome. No report, however, has addressed which infants should receive in delivery room. Therefore, aim this study was to assess validity identifying need based on fraction inspiratory oxygen ( FiO 2 ) requirement Methods In observational, retrospective study, given room, use therapy, stable microbubble test SMT...
Pallister-Hall syndrome (PHS) is defined as a group of characteristic manifestations caused by monoallelic GLI3 pathogenic variant. A two-month-old infant was referred to our institution because undetermined sex. The had atypical genitalia with postaxial polysyndactyly, hypothalamic mass, and an imperforate anus. We identified known variant the gene within one week diagnosed PHS. parents assigned male, considering 46,XY karyotype, normal testosterone secretion, possible male identity,...
Abstract OBJECTIVE: We aimed to present the active management and outcomes of infants born at 22 weeks gestation. STUDY DESIGN: This retrospective observational study presented resuscitation methods, during hospitalization, 29 gestation who were actively resuscitated admitted our center 2013–2020. RESULTS: The survival rate was 82.8% (24/29). Tracheal intubation performed in all patients, surfactant given for 27 (93.1%). Conventional mechanical ventilation introduced (93.1%), this changed...
Patent ductus arteriosus (PDA) causes severe morbidity in premature infants. Although the use of indomethacin is standard therapy for PDA, it sometimes not applicable because its adverse effects, such as renal and platelet dysfunctions. Paracetamol has emerged an alternative to owing excellent safety profile Of recently reported case series clinical trials on paracetamol there are few reports Japan preterm Furthermore, indications PDA have been approved PDA. While intravenous infants treated...