A5101622617- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Birth, Development, and Health
- Nutritional Studies and Diet
- HIV-related health complications and treatments
- Clinical practice guidelines implementation
- HIV Research and Treatment
- Health Promotion and Cardiovascular Prevention
- Health and Wellbeing Research
- Nuclear Receptors and Signaling
- Hepatocellular Carcinoma Treatment and Prognosis
Seoul National University Hospital
2015
University of Miami
2014
Seoul National University
2009
The strategies to protect against the disrupted blood–brain barrier (BBB) in HIV-1 infection are not well developed. Therefore, we investigated potential of peroxisome proliferator-activated receptor (PPAR) agonists prevent enhanced BBB permeability induced by HIV-1-specific protein Tat. Exposure Tat via internal carotid artery (ICA) across BBB; however, this effect was attenuated mice treated with fenofibrate (PPAR α agonist) or rosiglitazone γ agonist). In contrast, exposure GW9662...
An elevated mean corpuscular volume (MCV) is associated with aging, nutrition, alcohol abuse and more, it known as a survival predictor in chronically ill patients. The aim of this study was to investigate the association between MCV levels mortality from all-causes, cancer site-specific non-anemic healthy population.A total 36,260 participants aged 40 years or older who underwent routine check-ups at Seoul National University Hospital Health Promotion Center 1995 2008 were followed-up for...
Hepatocellular carcinoma (HCC) is one of the major cancers with a high incidence and mortality in Korea. A Korean multidisciplinary collaborative committee consisting hepatologists, radiologists, epidemiologists family medicine doctors systematically reviewed clinical practice guidelines world literatures. The level evidence for each recommendation was assessed discussed to reach consensus. Meta-analysis also conducted evaluate grade five key questions. Several randomized controlled studies...
Periodic Health Examination and Prevention Guidelines for Koreans were first proposed since 1988.Based on that guideline, clinical preventive services has been applied to clinic population in a few University Hospitals 1991.In 1995, LHMP development committee Korean Academy of Family Physician Society published evidence based practice guidelines updated the 2003.Lifetime Maintenance Program (LHMP) commitee represents efforts take more evidence-based approach third guideline 2009.We focused...