Yong-Lai Feng

ORCID: 0000-0002-0353-7239
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About
Contact & Profiles
Research Areas
  • Effects and risks of endocrine disrupting chemicals
  • Analytical chemistry methods development
  • Electrochemical Analysis and Applications
  • Toxic Organic Pollutants Impact
  • Carcinogens and Genotoxicity Assessment
  • Metabolomics and Mass Spectrometry Studies
  • Microfluidic and Capillary Electrophoresis Applications
  • Air Quality and Health Impacts
  • Advanced Chemical Sensor Technologies
  • Mercury impact and mitigation studies
  • Chemical Analysis and Environmental Impact
  • Mass Spectrometry Techniques and Applications
  • Sulfur-Based Synthesis Techniques
  • Analytical Chemistry and Chromatography
  • Radioactive contamination and transfer
  • Indoor Air Quality and Microbial Exposure
  • Microplastics and Plastic Pollution
  • Per- and polyfluoroalkyl substances research
  • Chemical Synthesis and Reactions
  • Health, Environment, Cognitive Aging
  • Nanopore and Nanochannel Transport Studies
  • Biological Control of Invasive Species
  • Synthesis and Catalytic Reactions
  • Prenatal Substance Exposure Effects
  • Synthesis and Reactivity of Sulfur-Containing Compounds

Health Canada
2012-2025

Hunan Agricultural University
2019

Changsha University
2019

State Council of the People's Republic of China
2019

Xishuangbanna Tropical Botanical Garden
2012

Shenyang Agricultural University
2012

Environment and Climate Change Canada
2007

Quality Research
2007

Southern Illinois University Carbondale
2007

Nanjing University
1993-1999

Dechlorane plus (DP), a flame retardant recently identified in the air and sediment of Great Lakes region, has been detected residential indoor dust city Ottawa, Canada using gas chromatography−mass spectrometry under negative chemical ionization mode. DP was all samples with concentration range 2.3 to 182 ng g-1, except for one sample (5683 g-1) which much higher. The levels were several times higher than those Lakes. presence environments could have implications potential human exposure...

10.1021/es071716y article EN Environmental Science & Technology 2007-10-10

DNA methylation is one of the epigenetic mechanisms that regulates gene expression, chromosome structure, and stability. Our objective was to determine whether system could be a target following in utero postnatal exposure human blood contaminants. Pregnant rats were dosed daily from gestation day 1 until 21 with 2 dose levels either organochlorine pesticides (OCP; 0.019 or 1.9 mg/kg/day), methylmercury chloride (MeHg; 0.02 polychlorinated biphenyls (PCBs; 0.011 1.1 mixture (Mix; 0.05, 5...

10.1177/1091581809337918 article EN International Journal of Toxicology 2009-07-01

A simple, practical and metal-free method has been developed for the synthesis of sulfonamides β-arylsulfonyl enamines via selective cleavage C-N C-H bonds through iodine-catalyzed oxidation arenesulfonyl chlorides sodium sulfinates with tert-amines. The uses commercially available inexpensive catalysts oxidants, a wide substrate scope operational simplicity.

10.1039/c8ob02992j article EN Organic & Biomolecular Chemistry 2019-01-01

Hexachlorocyclopentadienyl-dibromocyclooctane (HCDBCO, CAS 51936-55-1) has been detected in residential indoor air and dust Ottawa, Canada. The positive identification of the chemical was based on interpretation mass spectra obtained under both electron impact negative ionization operation modes, as well through synthesis this chemical. This is first report presence HCDBCO environment. Although levels dust, with a geometric mean 2.7 ng g−1 median 2.0 respectively, are generally low compared...

10.1021/es702272s article EN Environmental Science & Technology 2007-12-19

ABSTRACT This study assessed the influence of cigarette smoke condensate (CSC) and benzo(a)pyrene [B(a)P] on levels two oxidative stress biomarkers [8‐isoprostane (8‐IsoP) 8‐hydroxy‐2‐deoxy Guanosine (8‐OH‐dG)], in in‐vitro spent media follicle cells. Follicles (100–130 µm) isolated from ovaries F 1 hybrid (C57Bl/6j × CBA/Ca) mice were cultured for 13 days exposed to B(a)P [0 ng ml –1 (control) 45 ] or CSC µg 130 ]. The concentrations quantified by enzyme‐linked immune sorbent assays...

10.1002/jat.2884 article EN Journal of Applied Toxicology 2013-05-30

Endocrine disrupting chemicals are of concern because possible human health effects, thus they frequently included in biomonitoring studies. Current analytical methods focused on known and incapable identifying or quantifying other unknown their metabolites. Non-targeted analysis (NTA) advantageous since allow for broad chemical screening, which provides a more comprehensive characterization exposure, can elucidation metabolic pathways chemicals. There still many challenges associated with...

10.1016/j.chemosphere.2024.142754 article EN cc-by-nc Chemosphere 2024-07-02

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10.2139/ssrn.4760242 preprint EN 2024-01-01

Passive samplers have become more popular in their application the measurement of airborne chemicals. For volatile organic compounds, rate a chemical's diffusivity is determining factor quantity chemical being collected for given passive sampler. While uptake sampler can be determined either by collocation deployment both active and or use controlled facilities such as environmental chambers, new approach without need accurate flow experiment was demonstrated this study. This uses chemicals...

10.1039/c1em10278h article EN Journal of Environmental Monitoring 2011-01-01

The interaction of chemicals with DNA may lead to genotoxicity, mutation or carcinogenicity. A simple open tubular capillary electrochromatographic method is proposed rapidly assess the affinity three environmental contaminants (1,4-phenylenediamine, pyridine and 2,4-diaminotoluene) by measuring their retention in capillaries coated probes. oligonucleotide probes were immobilized on inner wall a fused silica that was first derivatized 3-(aminopropyl)-triethoxysilane (APTES). difference times...

10.1371/journal.pone.0153081 article EN cc-by PLoS ONE 2016-04-07
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