A5024890415- Angiogenesis and VEGF in Cancer
- PI3K/AKT/mTOR signaling in cancer
- Melanoma and MAPK Pathways
- Immune cells in cancer
- Cell Adhesion Molecules Research
- Colorectal Cancer Treatments and Studies
- Cancer Mechanisms and Therapy
Korea Research Institute of Bioscience and Biotechnology
2022
Sungkyunkwan University
2022
Identifying biomarkers related to the diagnosis and treatment of gastric cancer (GC) has not made significant progress due heterogeneity tumors. Genes involved in histological classification genetic correlation studies are essential develop an appropriate for GC.In vitro vivo lentiviral shRNA library screening was performed. The expression Synaptotagmin (SYT11) tumor tissues patients with GC confirmed by performing Immunohistochemistry, between level patient's survival rate analyzed....
The tumor microenvironment comprising blood vessels, fibroblasts, immune cells, and the extracellular matrix surrounding cancer has recently been targeted for research in therapy. We aimed to investigate effect of macrophages on invasive ability gastric studied their potential mechanism. In transcriptome analysis, integrin αV was identified as a gene increased AGS cells cocultured with RAW264.7 cells. displayed adhesion greater invasiveness compared cultured alone. This invasion inhibited by...