A5060457951- Lattice Boltzmann Simulation Studies
- Aerosol Filtration and Electrostatic Precipitation
- Heat and Mass Transfer in Porous Media
- Advanced Mathematical Modeling in Engineering
- Surface Modification and Superhydrophobicity
- Advanced MRI Techniques and Applications
- Coronary Interventions and Diagnostics
- Cardiovascular Health and Disease Prevention
- Angiogenesis and VEGF in Cancer
- Fluid Dynamics and Turbulent Flows
- Metallurgical Processes and Thermodynamics
- Health Systems, Economic Evaluations, Quality of Life
- Gas Dynamics and Kinetic Theory
- Microfluidic and Bio-sensing Technologies
- Retinal Imaging and Analysis
- Characterization and Applications of Magnetic Nanoparticles
University College London
2014-2018
Eindhoven University of Technology
2011-2014
University of Stuttgart
2011-2012
Computational Physics (United States)
2012
Over the last two decades, lattice Boltzmann methods have become an increasingly popular tool to compute flow in complex geometries such as porous media. In addition single phase simulations allowing, for example, a precise quantification of permeability sample, number extensions method are available which allow study multiphase and multicomponent flows on pore scale level. this article, we give extensive overview these diffuse interface models discuss their advantages disadvantages....
There is currently limited understanding of the role played by haemodynamic forces on processes governing vascular development. One many obstacles to be overcome being able measure those forces, at required resolution level, vessels only a few micrometres thick. In current paper, we present an in silico method for computation experienced murine retinal vasculature (a widely used development animal model) beyond what measurable experimentally. Our results show that it possible reconstruct...
We describe a generalization of the tensorial slip boundary condition, originally justified for thick (compared to texture period) channel, any channel thickness. The eigenvalues effective length tensor, however, in general case become dependent on gap and cannot be viewed as local property surface, being global characteristic channel. To illustrate use tensor formalism we develop semi-analytical theory an parallel-plate with one super-hydrophobic striped hydrophilic surface. Our approach is...
Droplets on hydrophobic surfaces are ubiquitous in microfluidic applications and there exists a number of commonly used multicomponent multiphase lattice Boltzmann schemes to study such systems. In this paper we focus popular implementation model as introduced by Shan Chen. Here, interactions between different components implemented repulsive forces whose strength is determined parameters. present simulations droplet surface. We investigate the dependence contact angle simulation parameters...
We introduce the lattice-Boltzmann code LB3D, version 7.1. Building on a parallel program and supporting tools which have enabled research utilising high performance computing resources for nearly two decades, LB3D 7 provides subset of functionality as an open source project. Here, we describe theoretical basis algorithm well computational aspects implementation. The software package is validated against simulations meso-phases resulting from self-assembly in ternary fluid mixtures...
Drug targeting promises to substantially enhance future therapies, for example through the focussing of chemotherapeutic drugs at site a tumor, thus reducing exposure healthy tissue unwanted damage. Promising work on steering medication in human body employs magnetic fields acting nanoparticles made paramagnetic materials. We develop computational tool aid optimization physical parameters these particles and configuration, estimating fraction reaching given target large patient-specific...
Anisotropic super-hydrophobic surfaces have the potential to greatly reduce drag and enhance mixing phenomena in microfluidic devices. Recent work has focused mostly on cases of stripes. Here, we analyze a relevant situation cosine variation local slip length. We derive approximate formulae for maximal (longitudinal) minimal (transverse) directional effective lengths that are good agreement with exact numerical solution lattice-Bolzmann simulations any surface fraction. The texture can...
Cerebrovascular diseases such as brain aneurysms are a primary cause of adult disability. The flow dynamics in arteries, both during periods rest and increased activity, known to be major factor the risk aneurysm formation rupture. precise relation is however still an open field investigation. We present automated ensemble simulation method for modelling cerebrovascular blood under range regimes. By automatically constructing performing multiscale simulations, where we unidirectionally...
By means of lattice-Boltzmann simulations the drag force on a sphere radius R approaching superhydrophobic striped wall has been investigated as function arbitrary separation h. Superhydrophobic (perfect-slip vs. no-slip) stripes are characterized by texture period L and fraction gas area ϕ. For very large values h/R, we recover macroscopic formulae for moving towards hydrophilic no-slip plane. h/R = O(1), is smaller than predicted classical theories surfaces, but larger expected interacting...
Many modern production and measurement facilities incorporate multiphase systems at low pressures. In this region of flows small, non-zero Knudsen- Mach numbers the classical mesoscopic Monte Carlo methods become increasingly numerically costly. To increase numerical efficiency simulations hybrid models are promising. contribution, we propose a novel efficient simulation approach for two phase with large concentration imbalance in pressure environment intermediate Knudsen regime. Our model...
Objective: We calculate quality-adjusted life years (QALY) and incremental cost-effectiveness ratio (ICER) for the use of interventional decentralized telemonitoring (idTM) in hypertension therapy. Both values are key performance indicators cost-benefit analysis medical interventions. The calculations compare blood pressure adjustment correlated reduction risk morbidity mortality between idTM standard therapy (ST). Prior studies have shown to significantly reduce time required reach targets...