A5069480043- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Liquid Crystal Research Advancements
- Spinal Cord Injury Research
- Cervical and Thoracic Myelopathy
- Pancreatic and Hepatic Oncology Research
- Musculoskeletal pain and rehabilitation
- Color Science and Applications
- Surface Roughness and Optical Measurements
- Neurogenesis and neuroplasticity mechanisms
- Nerve injury and regeneration
- Advanced Optical Imaging Technologies
- Photonic Crystals and Applications
- Spinal Dysraphism and Malformations
- Scoliosis diagnosis and treatment
- Neuroendocrine Tumor Research Advances
- Pain Mechanisms and Treatments
- Nerve Injury and Rehabilitation
- Medical Imaging and Analysis
- Lung Cancer Diagnosis and Treatment
- Advanced optical system design
- Industrial Vision Systems and Defect Detection
- Pelvic and Acetabular Injuries
- Neuroinflammation and Neurodegeneration Mechanisms
- Optical Polarization and Ellipsometry
Matsudo City Hospital
2011-2024
Chiba University
2007-2014
Tohoku University
1994-2007
Kyushu University
2006
Kanazawa Institute of Technology
2006
Tokyo Metropolitan University
2001
Toyama Prefectural Central Hospital
2001
Kanazawa University
1995
Nippon Medical School
1994
Granulocyte colony-stimulating factor (G-CSF) is a protein that stimulates differentiation, proliferation, and survival of granulocytic lineage cells. Recently, neuroprotective effect G-CSF was reported in model cerebral infarction. The aim the present study to elucidate potential therapeutic for spinal cord injury (SCI) mice. We found against glutamate-induced cell death cerebellar granule neurons vitro. Moreover, we used mouse compressive SCI examine vivo. Histologic assessment with cresyl...
Wnt proteins are a large family of diffusible factors that play important roles in embryonic development, including axis patterning, cell fate specification, proliferation, and axon development. It was recently demonstrated Ryk (receptor related to tyrosine kinase) is conserved high-affinity receptor, Ryk-Wnt interactions guide corticospinal axons down the spinal cord during Here, we report signal mediates inhibition growth adult cord. The expression Wnt-5a induced reactive astrocytes around...
Background Granulocyte colony-stimulating factor (G-CSF) is a protein that stimulates differentiation, proliferation, and survival of cells in the granulocytic lineage. Recently, neuroprotective effect G-CSF was reported model cerebral infarction we previously same studies murine spinal cord injury (SCI). The aim present study to elucidate potential therapeutic for SCI rats. Methods Adult female Sprague-Dawley rats were used study. Contusive introduced using Infinite Horizon Impactor...
An open-labeled multicenter prospective nonrandomized controlled clinical trial.To confirm the feasibility of using granulocyte colony-stimulating factor (G-CSF) for treatment acute spinal cord injury (SCI).We previously reported that G-CSF promotes functional recovery after compression-induced SCI in mice. On basis these findings, we conducted a trial to assess therapy patients with SCI.The ran from August 2009 March 2011, and included 41 treated within 48 hours onset. Informed consent was...
The authors previously reported that Schwann cells (SCs) could be derived from bone marrow stromal (BMSCs) in vitro and they promoted axonal regeneration of completely transected rat spinal cords vivo. aim the present study is to evaluate efficacy transplanted BMSC-derived SCs (BMSC-SCs) a model cord contusion, which relevant clinical injury.Bone were cultured as plastic-adherent GFPtransgenic rats. BMSC-SCs BMSCs with sequential treatment using beta-mercaptoethanol, all-trans-retinoic acid,...
Abstract To measure the pretilt angle in a liquid crystal cell, rotation method is commonly used because it very precise and measurement time short. However, if cell gap not uniform, significant error occurs due to shift of point. This caused by refraction at glass plate when rotating cell. In this paper, we estimate magnitude theoretically experimentally propose an improvement which accurate value can be obtained even uniform. Key Words: crystalpretilt anglecrystal methodmeasurement
Reactive "polymer nanosheets" consisting of N-dodecylacrylamide and a photocrosslinkable methacryloyl group in the polymer monolayer have been deposited onto solid substrates by Langmuir–Blodgett technique. The nanosheets well-ordered molecular alignment controlled thickness on nanoscale. Multiple photopatterning allows formation 3D nanostructures, such as pyramids, tracery patterns, etc. (see Figure), with nanometer precision. scale bar bottom figure represents 5.0 mm. Supporting...
Case series.To analyze factors that contribute to the development of sleep apnea in patients with rheumatoid arthritis (RA) and upper cervical lesions.No large prospective study has analyzed association between involvement resulting from RA. Furthermore, only 1 report literature describes a case accompanying vertical subluxation odontoid process.The authors 8 consecutive RA lesions who underwent occipitocervical (O-C) fusion. The were examined all-night polysomnography before after surgery....
A retrospective clinical and radiographical study.To assess the outcomes fusion rate of facet (FF) for degenerative lumbar spondylolisthesis (DLS).On basis long-term radiological follow-up studies posterolateral (PLF)-that is, intertransverse process with pedicle screw instrumentation-for DLS, we recognized that FF alone would be sufficient spinal fusion.Eighty-eight patients who underwent single-level DLS were retrospectively reviewed after at least 1 year follow-up. The control group...
An open-labeled multicenter prospective controlled clinical trial.To confirm the feasibility of granulocyte colony-stimulating factor (G-CSF) administration for patients with thoracic myelopathy.Although G-CSF is best known as an important cytokine commonly used to treat neutropenia, it also has nonhematopoietic functions. Previous experimental studies have shown that can enhance tissue regeneration several organs, such heart and brain. We previously reported promotes functional recovery...
To examine the effects of conservative and surgical treatments for nocturnal leg cramps in patients with lumbar spinal stenosis (LSS). Nocturnal is frequently observed peripheral neuropathy. However, there have been few reports on relationship between LSS, it remains unknown whether or intervention has an impact LSS.The subjects were 130 LSS low back pain. Conservative treatment such as exercise, medication, epidural block was used 66 decompression fusion performed 64 patients. Pain scores...
The pain of hip osteoarthritis (OA) is generally recognized as nociceptive in origin because the local pathology. However, some patients with OA experience a neuropathic component an essential part nociplastic subtype. Here, we sought to examine mechanism chronic symptomatic by association its distribution, complex screening, and prevalence lumbar spinal stenosis.We conducted prospective cross-sectional study 100 hips state. We examined all baseline clinical characteristics including...
Abstract Three‐dimensional (3D) displays without using any special glasses such as parallax barrier method and lenticular are actively researched recently. However, a high resolution display is difficult to obtain by these methods because of the limitation due pitch or lens. Then, we have proposed new solve this problem. In method, light from back‐light controlled in required direction, different images displayed according each direction. An observer receives 3D changing direction on liquid...
Abstract A color‐field sequential LCD using advanced OCB mode liquid crystal cell and an LED backlight has been developed. Application of a wide‐viewing‐angle‐wide‐band type circular polarizer realized wide viewing angle high transmittance LC cell. This paper describes the concept optical compensation fundamental characteristics LCD.
Study Design Retrospective case-control study. Purpose To determine whether kissing spine is a risk factor for recurrence of sciatica after lumbar posterior decompression using spinous process floating approach. Overview Literature Kissing defined by apposition and sclerotic change the facing processes as shown in X-ray images, often accompanied marked disc degeneration decrement height. If significantly contributes to weight bearing stability spine, trauma might induce breakdown surgery...