A5044027417- Healthcare and Venom Research
- Acupuncture Treatment Research Studies
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Studies
- Inflammasome and immune disorders
- Immune cells in cancer
- Macrophage Migration Inhibitory Factor
- Medical Research and Treatments
- Complementary and Alternative Medicine Studies
- Cytokine Signaling Pathways and Interactions
- Rheumatoid Arthritis Research and Therapies
- Metallurgical Processes and Thermodynamics
- Additive Manufacturing Materials and Processes
- Dermatology and Skin Diseases
- Lipid metabolism and disorders
- Microfinance and Financial Inclusion
- FinTech, Crowdfunding, Digital Finance
- High Temperature Alloys and Creep
- High-Temperature Coating Behaviors
- Sharing Economy and Platforms
- Nuclear Receptors and Signaling
- Bone Metabolism and Diseases
- Management Theory and Practice
- Cancer Mechanisms and Therapy
- FOXO transcription factor regulation
First Affiliated Hospital of Chengdu Medical College
2021-2025
Chengdu University of Traditional Chinese Medicine
2019-2024
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2024
Shanghai University of Traditional Chinese Medicine
2024
Centre of Excellence for Advanced Materials
2022-2023
Shenzhen University
2021
Chengdu University
2020
Weatherford College
2019
Objective Investigating the association between inflammatory cytokines and hypothyroidism remains challenging due to limitations in traditional observational studies. In this study, we employed Mendelian randomization (MR) assess causal relationship 41 hypothyroidism. Method Inflammatory 30,155 individuals of European ancestry with a GWAS summary containing 8,293 healthy participants were included study for bidirectional two-sample MR analysis. We utilized inverse variance weighting (IVW),...
Ethnopharmacological relevanceAstragalus polysaccharide (APS), the most biologically active ingredient of Astragali Radix, is used to treat diabetes mellitus (DM)-related chronic wounds in traditional Chinese medicine for several decades. This herb possesses an anti-inflammatory effect. Our study proved that APS can reduce excessive inflammation at late phase wound-healing diabetic ulcers.Aim studyTo clarify molecular mechanism promoting via reducing ulcers during stages...
Rheumatoid arthritis (RA) is a systemic and chronic autoimmune inflammatory disease characterized by severe synovial hyperplasia associated with progressive cartilage degradation. Due to the pain disability caused RA, effective therapeutic strategies that could simultaneously alleviate response delay progression are urgently needed. As major alternative therapy in traditional Chinese medicine, moxibustion has been demonstrated it reduce responses of series musculoskeletal diseases; however,...
Rheumatoid arthritis (RA) is an autoimmune disease characterized by systemic inflammation, especially synovitis, leading to joint damage. It important explore potential biomarkers and therapeutic targets improve the clinical treatment of RA. However, underlying mechanisms action available treatments for RA have not yet been fully elucidated. The present study investigated identified specific intervention. A comprehensive analysis was performed using mRNA files downloaded from Gene Expression...
Prior research has documented the association between certain circulating inflammatory proteins/immune cells and gout. However, reliability of these associations remains contentious due to constraints conventional observational methodologies. This investigation seeks reassess causative link gout through application Mendelian randomization (MR). The study included 3576 individuals European ancestry with gout, immune cell data from GWAS summary 3757 Sardinians, protein 14,824 participants for...
OBJECTIVE To explore the mechanism of moxibustion on treatment rheumatoid arthritis (RA) in perspective programmed cell death-1 and its ligand 1 (PD-1/PD-L1). METHODS A total 30 Japanese big ear white rabbits were randomly divided into a control group, model group 10 each one. In RA was prepared by injection Freund's complete adjuvant (FCA) hind knee joint cavities rabbit. 0.9% sodium chloride solution same dose injected. On 8th day experiment, applied to Shenshu (BL 23) Zusanli (ST 36), 5...
To observe the effects of moxibustion on T cells and cell immunoglobulin mucin-domain-containing molecule-3/galectin-9 (Tim-3/Gal-9) pathway in rats with rheumatoid arthritis (RA). further explore possible anti-inflammatory mechanism treatment RA. Thirty Sprague Dawley were randomly divided into three groups, including a control group, an RA model group. An was created through injection Freund's complete adjuvant. In treated at acupoints "Shenshu" "Zusanli." A total courses conducted. Then...
Obesity is a growing chronic health problem worldwide. Studies about acupuncture for obesity treatment are many. But there some doubts the effectiveness of vs sham in treating due to its lack an evidence-based medical proof. Therefore, aim this study assess efficacy and provide clinic evidence.This protocol was based on previous reporting items systematic review meta-analysis agreements. Four English databases (PubMed, EMBASE, Web Science, Cochrane Central Register Controlled Trials) 4...
Rheumatoid arthritis (RA) is an autoimmune disease that starts with inflammation of the synovium. The pain and joint dysfunction caused by RA urgently need effective treatment to alleviate inflammatory reaction delay progression disease. pathological damage proposed associate programmed cell death 1/programmed ligand 1 (PD-1/PD-L1) pathway. Moxibustion, as a main complementary therapy traditional Chinese medicine (TCM), has been proved reduce chronic on RA, but whether anti-inflammatory...
Objective To evaluate the therapeutic effect of point-injection anesthesia for thyroid operation. Methods 123 patients with diseases requiring treatment by surgery were randomly allocated to two groups: experimental group included 61 cases who anesthetized point-injection; control 62 cervial plexum block. Differences in onset time anesthesia, VRS evaluated 30 minutes after injection, SBP, DBP, HR before opreration, at beginning operation, end incidence nausea and vomiting during post...