A5051751538- Education, sociology, and vocational training
- Cultural Insights and Digital Impacts
- Photosynthetic Processes and Mechanisms
- RNA and protein synthesis mechanisms
- scientometrics and bibliometrics research
- Competitive and Knowledge Intelligence
- Algal biology and biofuel production
- Enzyme Structure and Function
- Social Sciences and Governance
- Protein Structure and Dynamics
- Healthcare Systems and Practices
- International Development and Aid
- Bioinformatics and Genomic Networks
- Bacterial Identification and Susceptibility Testing
- Genomics and Phylogenetic Studies
- Religion, Society, and Development
- Social Policies and Family
- Conferences and Exhibitions Management
- Natural Language Processing Techniques
- Molecular Biology Techniques and Applications
- Academic Publishing and Open Access
- Cancer Research and Treatments
- Machine Learning in Bioinformatics
- Health, Medicine and Society
- Electrochemical sensors and biosensors
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2005-2023
CEA Cadarache
2023
CEA Grenoble
2023
CEA Paris-Saclay - Etablissement de Saclay
2023
CEA Paris-Saclay
2023
Université d'Évry Val-d'Essonne
2021
Société Française de Cardiologie
2020
Agency for Science, Technology and Research
2011
Vrije Universiteit Brussel
2001-2006
Vlaams Instituut voor Biotechnologie
2001
FoldX is an empirical force field that was developed for the rapid evaluation of effect mutations on stability, folding and dynamics proteins nucleic acids. The core functionality FoldX, namely calculation free energy a macromolecule based its high-resolution 3D structure, now publicly available through web server at http://foldx.embl.de/. current release allows stability protein, positions protons prediction water bridges, metal binding sites analysis complex formation. Alanine scanning,...
Single nucleotide variants (SNVs) are, together with copy number variation, the primary source of variation in human genome and are associated phenotypic such as altered response to drug treatment susceptibility disease. Linking structural effects non-synonymous SNVs functional outcomes is a major issue bioinformatics. The SNPeffect database (http://snpeffect.switchlab.org) uses sequence- structure-based bioinformatics tools predict effect protein-coding on phenotype proteins. It integrates...
We have developed a web tool, PupaSuite, for the selection of single nucleotide polymorphisms (SNPs) with potential phenotypic effect, specifically oriented to help in design large-scale genotyping projects. PupaSuite uses collection data on SNPs from heterogeneous sources and large number pre-calculated predictions offer flexible intuitive interface selecting an optimal set SNPs. It improves functionality PupaSNP PupasView programs implements new facilities such as analysis user's derive...
p13suc1 has two native states, a monomer and domain-swapped dimer. We show that their folding pathways are connected by the denatured state, which introduces kinetic barrier between dimer under conditions. The is lowered conditions speed up unfolding, thereby allowing, to our knowledge for first time, quantitative dissection of energetics domain swapping. monomer–dimer equilibrium controlled conserved prolines in hinge loop connects exchanging domains. These residues exploit backbone strain...
We describe here the complete amino acid sequence of photosystem I subunit IV from Synechocystis 6803. The molecular mass 8.0 kDa is lower than in higher plants and Chlamydomonas , due to lack a characteristic, proline‐rich, N‐terminal sequence. remaining exhibits good conservation, with hydrophilic strongly basic N‐tenninal head followed by two hydrophobic domains. There no possibility classical membrane‐spanning alpha helices. This component likely be one most stroma accessible subunits I.
12 Ar ( abes ) ques N°103 OCTOBRE