A5032700354- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Immune responses and vaccinations
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Metabolomics and Mass Spectrometry Studies
- Vaccine Coverage and Hesitancy
- Bacterial Identification and Susceptibility Testing
- COVID-19 Prevention and Impact
- Pneumonia and Respiratory Infections
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Long-Term Effects of COVID-19
- COVID-19 Impact on Reproduction
Ospedale Monaldi
2021-2024
SARS-CoV-2 infection is characterized by several clinical manifestations, ranging from the absence of symptoms to severe forms that necessitate intensive care treatment. It known patients with highest rate mortality develop increased levels proinflammatory cytokines, called “cytokine storm”, which similar inflammatory processes occur in cancer. Additionally, induces modifications host metabolism leading metabolic reprogramming, closely linked changes A better understanding correlation...
Background: The monocyte-phagocyte system (MPS), including monocytes/macrophages and dendritic cells (DCs), plays a key role in anti-viral immunity. We aimed to analyze the prognostic value of MPS components on in-hospital mortality cohort 58 patients (M/F ; mean ageSD years) with COVID-19 pneumonia 22 age- sex-matched healthy controls. Methods: measured frequencies absolute numbers peripheral blood CD169+ monocytes, conventional CD1c+ CD141+ (namely cDC2 cDC1), plasmacytoid CD303+ DCs by...
real-world data on COVID-19 vaccine safety, immunogenicity and acceptance in adults with congenital heart disease (ACHD) are lacking.ACHD patients who were offered vaccination from January to June 2021 included. Data adverse events, patients' attitude towards antispike IgG titre retrospectively collected. A group of healthy individuals similar age sex undergoing was included for comparison.208 followed a single ACHD tertiary centre (33.3 [26-45] years, 54% male) received vaccine, 65%...
Abstract Background The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has unpredictable manifestations of disease (COVID-19) and variable clinical course some patients being asymptomatic whereas others experiencing distress, or even death. We aimed to evaluate the immunoglobulin G (IgG) response towards linear peptides on a peptide array containing sequences from SARS-CoV-2, Middle East syndrome-related (MERS) common-cold coronaviruses 229E, OC43, NL63 HKU1...
Background: The monocyte–phagocyte system (MPS), including monocytes/macrophages and dendritic cells (DCs), plays a key role in anti-viral immunity. We aimed to analyze the prognostic value of MPS components on in-hospital mortality cohort 58 patients (M/F; mean age ± SD years) with COVID-19 pneumonia 22 age- sex-matched healthy controls. Methods: measured frequencies absolute numbers peripheral blood CD169+ monocytes, conventional CD1c+ CD141+ (namely cDC2 cDC1), plasmacytoid CD303+ DCs by...
Abstract Introduction Candidemia can be a significant cause of death in immunosuppressed or debilitated patients particularly. Abnormalities the instrumental cytograms some hematological analyzers, such as Mindray BC‐6800Plus, related to circulating Candida. We studied possible diagnostic usefulness this information. Methods A fungal bloodstream infection has been simulated by adding aliquots Candida albicans , parapsilosis and glabrata 75 leftovers anonymized peripheral blood samples....