A5009832075- Escherichia coli research studies
- Bacterial Genetics and Biotechnology
- Microbial Metabolites in Food Biotechnology
- Antibiotic Resistance in Bacteria
- Microbial Metabolic Engineering and Bioproduction
- Gut microbiota and health
- Probiotics and Fermented Foods
- Diet and metabolism studies
- Evolution and Genetic Dynamics
- Legionella and Acanthamoeba research
- Animal Behavior and Welfare Studies
- Vibrio bacteria research studies
- Amino Acid Enzymes and Metabolism
- Salmonella and Campylobacter epidemiology
- Enzyme Structure and Function
- Biomedical Research and Pathophysiology
- Digestive system and related health
- Mycobacterium research and diagnosis
- Trace Elements in Health
- Bacterial Infections and Vaccines
- Radioactive element chemistry and processing
- Parasitic Infections and Diagnostics
- Human-Animal Interaction Studies
- Veterinary Practice and Education Studies
- Infant Nutrition and Health
Institut National de la Recherche Scientifique
2013-2017
Université de Montréal
2013-2017
Armand Frappier Museum
2012-2017
Université de Tours
2012
Institut National de la Recherche Agronomique
2012
Université Laval
2012
Infectiologie Animale et Santé Publique
2008-2011
ABSTRACT In Escherichia coli , the small regulatory noncoding RNA (sRNA) RyhB and global ferric uptake regulator (Fur) mediate iron acquisition storage control. Iron is both essential potentially toxic for most living organisms, making precise maintenance of homeostasis necessary survival. While roles these regulators in have been well studied a nonpathogenic E. strain, their impact on production virulence-associated factors still unknown pathogenic strain. We thus investigated Fur virulence...
Escherichia coli can cause extraintestinal infections in humans and animals. The hlyF gene is epidemiologically associated with virulent strains of avian pathogenic E. human neonatal meningitis–associated coli. We demonstrated that culture supernatants expressing HlyF induced autophagy eukaryotic cells. This phenotype coincided an enhanced production outer membrane vesicles (OMVs) by bacteria HlyF. protein displays a predicted catalytic domain the short-chain dehydrogenase/reductase...
We identified a carbohydrate metabolic operon (frz) that is highly associated with extraintestinal pathogenic Escherichia coli (ExPEC) strains. The frz codes for three subunits of phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) transporter the fructose subfamily, transcriptional activator PTSs MgA family, two type II ketose-1,6-bisphosphate aldolases, sugar-specific kinase (repressor, open reading frame, family [ROK]), and protein cupin superfamily. proved promotes bacterial...
Summary A gene cluster involved in the metabolism of prebiotic short‐chain fructooligosaccharides (scFOS) has recently been identified extra‐intestinal avian pathogenic Escherichia coli strain BEN2908. This cluster, called fos locus, plays a major role initiation stage chicken intestinal colonization. locus is composed six genes organized as an operon encoding sugar transporter and enzymes scFOS metabolism, divergently transcribed transcriptional regulator, FosR, belonging to LacI/GalR...
Extra-intestinal pathogenic Escherichia coli (ExPEC) strains cause many diseases in humans and animals. While remaining asymptomatic, they can colonize the intestine for subsequent extra-intestinal infection dissemination environment. We have previously identified fos locus, a gene cluster within pathogenicity island of avian ExPEC strain BEN2908, involved metabolism short-chain fructooligosaccharides (scFOS). It is assumed that these sugars are metabolized by probiotic bacteria microbiota...
The pst gene cluster encodes the phosphate-specific transport (Pst) system. Inactivation of Pst system constitutively activates two-component regulatory PhoBR and attenuates virulence pathogenic bacteria. In uropathogenic Escherichia coli strain CFT073, attenuation by inactivation is predominantly attributed to decreased expression type 1 fimbriae. However, molecular mechanisms connecting fimbriae are unknown. To address this, a transposon library was constructed in mutant, clones were...
The yicJI operon of the common genetic backbone Escherichia coli codes an α-xylosidase and a transporter galactosides--pentoses--hexuronides:cation symporter family. In extraintestinal pathogenic E. strain BEN2908, metabolic (frz) seven genes is found downstream yicI gene. It was proved that frz promotes bacterial fitness under stressful conditions. During this work, we identified motif containing palindromic sequence in promoter region both operons. We then showed these two operons are...
Background: Separation-related disorders are prevalent in dogs and can result problem behaviours such as inappropriate elimination, destructive behaviour, distress vocalizations which occur when an owner is absent or perceived absent. Numerous natural products marketed for managing anxiety dogs; however, few, if any, of these have documented evidence efficacy veterinary behaviour. Purpose: This open, multicentric clinical trial aimed to assess the a new supplement containing alpha-casozepine...