A5002673886- Parathyroid Disorders and Treatments
- Bone health and treatments
- Bone health and osteoporosis research
- Vitamin D Research Studies
- Genetic Syndromes and Imprinting
- Pituitary Gland Disorders and Treatments
- Diabetes and associated disorders
- Diabetes Management and Research
- COVID-19 Clinical Research Studies
- Pancreatic and Hepatic Oncology Research
- Diet and metabolism studies
- Pancreatitis Pathology and Treatment
- Metabolism, Diabetes, and Cancer
- Neuroendocrine Tumor Research Advances
- Growth Hormone and Insulin-like Growth Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Medical Imaging and Pathology Studies
- Liver Disease Diagnosis and Treatment
- Celiac Disease Research and Management
- Thyroid and Parathyroid Surgery
- Adrenal and Paraganglionic Tumors
- Bone Metabolism and Diseases
- Digestive system and related health
- Pancreatic function and diabetes
Post Graduate Institute of Medical Education and Research
2016-2025
Endocrinology Research Center
2014-2025
Creative Commons
2017-2023
Chitkara University
2023
Regional Centre for Biotechnology
2023
Institute of Post Graduate Medical Education and Research
2009-2023
Collaborative Group (United States)
2022
Diabetes Australia
2021
Chandigarh University
2009-2018
Henry Ford Hospital
2017
To report presentation and outcome of rhino-orbital-cerebral mucormycosis (ROCM) exclusively in patients with diabetes mellitus.Retrospective, non-comparative, interventional analysis the medical records 35 ROCM among 22 316 seen over last 12 years.A cohort 23 men women a mean (SD) age 47.3 (14.4) years (range 18-70 years) was studied. Five had type 1 mellitus, 29 2 one secondary diabetes. Nine as first clinical manifestation The blood glucose at 20.6 (8.3) mmol/l 10.0 to 53.3 mmol/l) 17...
With the easy availability of thyroid hormone assays, disorders are now recognised even in a subclinical state. However, patients still seen with advanced manifestations disease, particularly developing countries. This observational study analysed predictors outcome myxoedema coma and tested validity different modules to define morbidity mortality these patients.
Although glycated hemoglobin (HbA1c) has recently been incorporated as a diagnostic test by the American Diabetes Association, its validity needs to be established in Asian Indians community setting.The objective of study was assess HbA1c screening and individuals with newly detected diabetes mellitus.Community based randomized cross sectional urban Chandigarh, city north India, from April 2008 August 2009.Subjects included 1972 subjects aged 20 yr or older.Intervention an oral glucose...
Purpose Accurate preoperative localization of parathyroid lesion(s) is crucial for successful surgical management primary hyperparathyroidism (PHPT). This study was conducted to compare the effectiveness ultrasonography (USG) neck, 99m Tc-sestamibi (MIBI) imaging with or without SPECT/CT, and 18 F-fluorocholine (FCH) PET/CT in lesions patients PHPT. Methods Fifty-four consecutive PHPT were included this prospective who underwent using 3 diagnostic modalities followed by surgery. The...
Background Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome, usually caused by small benign mesenchymal tumors. The localization of these tumors challenging, however, essential for the management. We compared utility 18F-FDG PET/CT and 68Ga DOTATATE to detect site primary tumor in patients with suspicion TIO. Patients Methods Retrospective analysis 6 hypophosphatemic TIO was performed. study performed all localize tumor. 4 patients. studies were within 1 week each other....
Abstract Context Increased bone fragility and reduced energy absorption to fracture associated with type 2 diabetes (T2D) cannot be explained by mineral density alone. This study, for the first time, reports on alterations in tissue’s material properties obtained from individuals known status. Objective To investigate role of T2D altering biomechanical, microstructural, compositional fracture. Methods Femoral head tissue specimens were collected patients who underwent replacement surgery hip...
Abstract Crohn’s and ulcerative colitis are common inflammatory conditions associated with Inflammatory bowel disease. Owing to the importance of diet based approaches for prevention gut conditions, present study was aimed screen human isolates Bifidobacterium strains on their ability reduce LPS-induced inflammation in murine macrophage (RAW 264.7) cells evaluate prioritized preventive efficacy against mice. Twelve out 25 isolated reduced production nitric oxide cytokines. Furthermore, three...
<h3>Importance</h3> Women with recent gestational diabetes (GDM) have increased risk of developing type 2 diabetes. <h3>Objective</h3> To investigate whether a resource-appropriate and context-appropriate lifestyle intervention could prevent glycemic deterioration among women GDM in South Asia. <h3>Design, Setting, Participants</h3> This randomized, participant-unblinded controlled trial investigated 12-month vs usual care at 19 urban hospitals India, Sri Lanka, Bangladesh. Participants...
Abstract Background efficacy of therapeutic cholecalciferol supplementation for severe COVID-19 is sparingly studied. Objective effect single high-dose on sequential organ failure assessment (SOFA) score in moderate-to-severe COVID-19. Methods participants with moderate to PaO2/FiO2 ratio &lt; 200 were randomized 0.6 million IU oral (intervention) or placebo. Outcomes primary outcome was change Day 7 SOFA and pre-specified secondary outcomes 28-day all-cause mortality. Results all, 90...
Abstract Introduction: Type 2 diabetes mellitus (T2DM) increases the risk of fragility fractures, despite fact that areal bone mineral density (aBMD) is either increased or normal compared to healthy non-diabetic subjects. Hence, trabecular score (TBS) under investigation in this patient cohort as an alternative metric for assessment health. The present study aimed determine TBS post-menopausal women diagnosed with T2DM and individuals. Methods: This cross-sectional enrolled 101 individuals...
Progressive and inexorable beta-cell dysfunction is the hallmark of type 2 diabetes mellitus (T2DM) regeneration using stem cell therapy may prove to be an effective modality. A total 10 patients (8 men) with T2DM for >5 years, failure triple oral antidiabetic drugs, currently on insulin (> or = 0.7 U/kg/day) at least 1 year, glutamic acid decarboxylase antibody negative were included. Patients stable doses medications past 3 months recruited. Primary end points reduction in requirement by >...
Background: Insulin resistance plays an important role in the pathogenesis of NAFLD. Pharmacological treatment patients with NAFLD is still evolving. sensitizing drugs like metformin may be effective these patients. Twenty five adult who did not achieve normalization alanine transaminases (ALT) after 6 months lifestyle interventions and UDCA were treated 500mg tid for months. was determined by HOMA-IR. Liver function tests done monthly defined having no response, partial response or complete...
Abstract Background and Aim: There is scanty data on the occurrence of celiac disease in patients with type 1 diabetes mellitus South Asia. Our aim was to study prevalence clinical profile a tertiary care referral centre north India. Methods: Consecutive attending Endocrine clinic our institute between January 2002 December 2008 were screened using anti‐tissue transglutaminase antibodies (tTGAb), those positive subjected duodenal biopsy. Clinical these recorded. Results: Out 189 mellitus, 21...