A5051917001- Childhood Cancer Survivors' Quality of Life
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Cardiac Arrest and Resuscitation
- Immune Response and Inflammation
- Dermatology and Skin Diseases
- E-Learning and Knowledge Management
- Higher Education Teaching and Evaluation
- Educational Technology in Learning
- Psoriasis: Treatment and Pathogenesis
- Immunodeficiency and Autoimmune Disorders
- Congenital Diaphragmatic Hernia Studies
- Maternal and Neonatal Healthcare
- Respiratory Support and Mechanisms
- Healthcare cost, quality, practices
- Emergency and Acute Care Studies
- Health Sciences Research and Education
- Dialysis and Renal Disease Management
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Ultrasound in Clinical Applications
- Neutropenia and Cancer Infections
- Galician and Iberian cultural studies
- Health Policy Implementation Science
- Mediterranean and Iberian flora and fauna
Hospital Universitario La Paz
2020-2025
Objectives: The Pediatric Sepsis Definition Task Force developed and validated a new organ dysfunction score, the Phoenix Score (PSS), as predictor of mortality in children with suspected or confirmed infection. PSS showed improved performance compared prior scores. However, criteria were derived general pediatric population, which only 10% had cancer. Given that cancer patients sepsis have higher noncancer sepsis, we aimed to assess PICU sepsis. Design: Retrospective multicenter cohort...
The Venous Excess Ultrasound (VExUS) score has been described as a useful tool to estimate the degree of venous congestion in adult patients. present study aimed analyze feasibility and usefulness VExUS detect grade central pressure (CVP) elevation critically ill children.A cross-sectional pilot was conducted tertiary-care pediatric intensive care unit between November 2020 June 2021. All children whom CVP monitored, were enrolled. At time catheter placement, determined, analyzing inferior...
Abstract Background Internationally, there is an increasing trend in using Rapid Response Systems (RRS) to stabilize in‐patient deterioration. Despite a growing evidence base, remains limited understanding of the processes place aid early recognition and response deteriorating children hospitals across Europe. Aim/s To describe for deterioration European hospitals. Study Design A cross‐sectional opportunistic multi‐centre study, with paediatric in‐patients, descriptive self‐reported,...
Abstract A 6‐year‐old girl presented with fever, skin rash, anuria, and conjunctivitis that rapidly progressed to toxic shock syndrome. Following hospital discharge, she developed a staphylococcal abscess on the lower extremity. She had recently received first two doses of interleukin‐17 (IL‐17) inhibitor secukinumab for resistant plaque psoriasis. IL‐17 is known be essential in host defense against Staphylococcus aureus . To our knowledge, this reported case syndrome (STSS) associated an inhibitor.
BackgroundIdentifying phenotypes in sepsis patients may enable precision medicine approaches. However, the generalisability of these to specific patient populations is unclear. Given that paediatric cancer with have different host response and pathogen profiles higher mortality rates when compared non-cancer patients, we determined whether unique, reproducible, clinically-relevant exist this population.MethodsWe studied underlying malignancies admitted one 25 intensive care units (PICUs)...
Adaptation of evidence-based interventions (EBIs) often occurs when implemented in new local contexts and settings. It is unclear, however, during which phase implementation adaptations are most frequently made how these changes may impact the fidelity, effectiveness, sustainability EBI. Pediatric Early Warning Systems (PEWS) EBIs for early identification deterioration hospitalized children with cancer. This study evaluates PEWS among resource-variable pediatric oncology hospitals Latin...
Background: Intensified treatment protocols have improved survival of pediatric oncology patients. However, these are associated with increased treatment-related morbidity requiring admission to intensive care unit (PICU). We aimed describe the organizational characteristics and processes for this patient group across PICUs in Europe. Methods: A web-based survey was sent PICU directors or representative physicians between February June 2021. Results: Responses were obtained from 77 12...
Background Intensified treatment protocols have improved survival of pediatric oncology patients. However, these are associated with increased treatment-related morbidity requiring admission to intensive care unit (PICU). We aimed describe the organizational characteristics and processes for this patient group across PICUs in Europe. Methods A web-based survey was sent PICU directors or representative physicians between February June 2021. Results Responses were obtained from 77 12 European...
Introduction: Hospitalized pediatric hematology-oncology (PHO) patients have frequent clinical deterioration events (CDE) requiring Intensive Care Unit (ICU) interventions and resulting in high mortality, particularly resource-limited settings. The objective of this study is to describe patterns risk factors for CDE mortality hospitalized PHO Latin America. Methods: In 2017, we implemented a prospective registry among centers participating quality improvement collaborative America (Proyecto...