A5006824871- Orthopaedic implants and arthroplasty
- Reconstructive Surgery and Microvascular Techniques
- Metal and Thin Film Mechanics
- Peripheral Artery Disease Management
- Coronary Interventions and Diagnostics
- Molecular Biology Techniques and Applications
- Dental materials and restorations
- Muscle Physiology and Disorders
- Mesenchymal stem cell research
- Scientific Measurement and Uncertainty Evaluation
- COVID-19 and healthcare impacts
- Metal Alloys Wear and Properties
- Bone fractures and treatments
- Adhesion, Friction, and Surface Interactions
- Orthopedic Infections and Treatments
- Aortic aneurysm repair treatments
- Food composition and properties
- Infection Control and Ventilation
- Forensic Anthropology and Bioarchaeology Studies
- Veterinary Equine Medical Research
- Smart Agriculture and AI
- Spectroscopy and Chemometric Analyses
- Anatomy and Medical Technology
- Thermal Regulation in Medicine
- Advanced Measurement and Metrology Techniques
Louisiana State University
2020-2023
Louisiana State University Agricultural Center
2023
Saint Louis University
2021
University of California, Santa Barbara
2013-2020
A novel, hand-held Reference Point Indentation (RPI) instrument, measures how well the bone of living patients and large animals resists indentation. The results presented here are reported in terms Bone Material Strength, which is a normalized measure indentation, inversely related to indentation distance into bone. We present examples instrument's use in: (1) laboratory experiments on bone, including through layer soft tissue, (2) three human clinical trials, two ongoing Barcelona at Mayo...
De novo limb regeneration after amputation is restricted in mammals to the distal digit tip. Central this regenerative process blastema, a heterogeneous population of lineage-restricted, dedifferentiated cells that ultimately orchestrates amputated bone and surrounding soft tissue. To investigate skeletal regeneration, we made use spatial transcriptomics characterize transcriptional profile specifically within blastema. Using technique, generated gene signature with high specificity for...
The bone material strength index (BMSi), as measured by the OsteoProbe, is significantly correlated with Vickers hardness and Rockwell (RW) measurements on conventional materials. RW were carried out according to American Society for Testing Materials standard test methods, OsteoProbe followed published standardized testing methods. correlations between BMSi hardness, r = 0.93, 0.94, are comparable correlation 0.87. significant at p < 0.01, 0.01. These results show that indentation...
Mouse digit amputation provides a useful model of bone growth after injury, in that the injury promotes intramembranous formation an adult animal. The tip is composed skin, nerves, blood vessels, bones, and tendons, all which regenerate amputation, making it powerful for multi-tissue regeneration. Bone integrity relies upon balanced remodeling between resorption formation, which, when disrupted, results changes to architecture biomechanics, particularly during aging. In this study, we used...
To compare results obtained with a handheld reference point indentation instrument for bone material strength index (BMSi) measurements in the equine third metacarpal various testing conditions.24 bones.Third bones from both forelimbs of 12 horses were obtained. The dorsal surface each was divided into 6 regions. In vivo and ex BMSi through skin on exposed bone, respectively, to determine effects condition. Difference plots used assess agreement between conditions. Linear regression analysis...
Abstract Bone is an essential, healing structure in vertebrates that ensures daily function. However, the regenerative capacity of bone declines with age, compromising quality life elderly and increasing cost care. Here, for first time, elasticity regenerated a mouse digit amputation model evaluated order to better investigate biomechanics skeletal regeneration. Amputation distal one third (third phalangeal element – P3) results de novo regeneration digit, where analyzing structural this...
Drug-coated angioplasty balloons (DCBs) are used to treat peripheral artery disease, and proper dosage depends on coating characteristics like uniformity number of layers.
Abstract At 4.44 billion bushels worth an estimated $57.7 dollars, soybeans are one of the most produced crops in United States and appraised using a standard grading system set by USDA(NASS, 2022). The inspection process is based on twenty factors, including six that visual (USDA, 2020). aim this research to apply texture-based image analysis assess indicators damage demonstrate potential use increasing efficiency consistency soybean grading. Surface texture characteristics examined...
In this study, we aim to quantify coating uniformity and correlate fluorescence intensity drug loading for drug-coated angioplasty balloons (DCB) coated with 5, 10, 15, or 20 layers of poly(lactic-co-glycolic acid) nanoparticles (NPs) entrapped quercetin. Uniformity was quantified from histograms horizontal line profiles microscopic fluorescent images acquired sample specific parameters, cracks in the were measured counted. The global parameters correlated quercetin via gravimetric/HPLC...
Older people are projected to outnumber children for the first time in U.S. history by 2030 (U.S. Census Bureau, 2017), creating a tsunami of with reduced bone strength who more susceptible injury and fracture. Decreased quality has multivariate causal path including loss progenitor cells, anabolic catabolic capabilities increased senescence. The age‐related cellular decline begins prior onset diseases such as osteoporosis. Thus, aging models exclusive disease can be immensely beneficial...
Abstract Objective Determine the effectiveness of evacuation systems designed to clear bioaerosols and smoke from surgical field. Study design High-speed photographic evaluation aerosol generated in simulated fields. Materials methods Surgical site clearance was evaluated using a model anterior neck prototypes for evacuator ports created 3D printing. A commercially available electrocautery handpiece fitted with an tested on animal tissue clearance. Both were connected commercial vacuum...