Donna T. Geddes

ORCID: 0000-0002-0431-7078
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About
Contact & Profiles
Research Areas
  • Breastfeeding Practices and Influences
  • Infant Nutrition and Health
  • Infant Health and Development
  • Birth, Development, and Health
  • Cleft Lip and Palate Research
  • Child Nutrition and Feeding Issues
  • Child Nutrition and Water Access
  • Neonatal Respiratory Health Research
  • Infant Development and Preterm Care
  • Pediatric health and respiratory diseases
  • Digestive system and related health
  • Gut microbiota and health
  • Gestational Diabetes Research and Management
  • Oral and Craniofacial Lesions
  • Fatty Acid Research and Health
  • Cancer Risks and Factors
  • Neuroscience of respiration and sleep
  • Obesity, Physical Activity, Diet
  • MicroRNA in disease regulation
  • Clinical Nutrition and Gastroenterology
  • Body Composition Measurement Techniques
  • Viral gastroenteritis research and epidemiology
  • Congenital Anomalies and Fetal Surgery
  • Milk Quality and Mastitis in Dairy Cows
  • Nutritional Studies and Diet

The University of Western Australia
2016-2025

Community Arts Network
2023-2025

Queensland Centre for Mental Health Research
2024-2025

Murdoch Children's Research Institute
2023

International Society for Research in Human Milk and Lactation
2022-2023

The Kids Research Institute Australia
2021-2022

Murdoch University
2021

Regional Energy Agency
2021

King Edward Memorial Hospital
2013

Western Australian Marine Science Institution
2006

Human milk (HM) is the optimal source of nutrition, protection and developmental programming for infants. It species-specific consists various bioactive components, including microRNAs, small non-coding RNAs regulating gene expression at post-transcriptional level. microRNAs are both intra- extra-cellular present in body fluids humans animals. Of these fluids, HM appears to be one richest sources microRNA, which highly conserved its different fractions, with cells containing more than...

10.3390/ijerph121113981 article EN International Journal of Environmental Research and Public Health 2015-10-30

There is evidence that infants with ankyloglossia can experience breastfeeding difficulties including poor attachment to the breast, suboptimal weight gain, and maternal nipple pain, which may lead early weaning of infant. No studies have investigated cause these difficulties. The objective this study was determine effectiveness frenulotomy in experiencing persistent despite professional assistance by measuring changes milk transfer tongue movement during before after frenulotomy.Twenty-four...

10.1542/peds.2007-2553 article EN PEDIATRICS 2008-06-24

Abstract Human milk (HM) contains regulatory biomolecules including miRNAs, the origin and functional significance of which are still undetermined. We used TaqMan OpenArrays to profile 681 mature miRNAs in HM cells fat, compared them with maternal peripheral blood mononuclear (PBMCs) plasma, bovine soy infant formulae. PBMCs (292 345 respectively) had higher miRNA content than fat plasma (242 219 ( p < 0.05). A strong association profiles was found between whilst were distinctly different...

10.1038/srep20680 article EN cc-by Scientific Reports 2016-02-08

Background: Persistent nipple pain is one of the most common reasons given by mothers for ceasing exclusive breastfeeding. We aimed to determine frequency as a reason consultation, attributed aetiologies, and effectiveness advice treatment given. Methods: All consultations at Breast Feeding Centre Western Australia (WA) were audited over two six-month periods in 2011 (n = 469) 2014 708). Attributed cause(s) pain, microbiology results, treatment(s) advised, resolution recorded. Results:...

10.3390/ijerph121012247 article EN International Journal of Environmental Research and Public Health 2015-09-29

Abstract There is a paucity of data on the effect preterm birth immunological composition breast milk throughout different stages lactation. We aimed to characterise effects levels immune factors in during 1st month postpartum, determine whether deficient antimicrobial factors. Colostrum (days 2–5 postpartum), transitional 8–12) and mature 26–30) were collected from mothers extremely (<28 weeks gestation, n 15), very (28–<32 moderately (32–<37 15) term infants (37–41 15). Total...

10.1017/s0007114516000234 article EN British Journal Of Nutrition 2016-02-19

Surgical release of the lingual frenulum (frenotomy) has become an increasingly common procedure, performed from birth through to adulthood. Surprisingly, detailed anatomy in‐situ never been described, and no anatomical basis proposed for individual variability in morphology. The is frequently referred as a “cord” or “submucosal band” connective tissue, yet there evidence support this construct. This paper aims describe its relationship floor mouth structures. Fresh tissue microdissection...

10.1002/ca.23343 article EN cc-by-nc-nd Clinical Anatomy 2019-01-31

Human milk (HM) appetite hormones and macronutrients may mediate satiety in breastfed infants. This study investigated associations between maternal adiposity concentrations of HM leptin, adiponectin, protein lactose, whether these the relationship body mass index percentage fat (%FM) a breastfeeding population change over first year lactation. Lactating women (n = 59) provided samples 283) at 2nd, 5th, 9th and/or 12th month Concentrations total lactose were measured. Maternal %FM was...

10.3390/nu9030252 article EN Nutrients 2017-03-09

Milk is rich in miRNAs that appear to play important roles the postnatal development of all mammals. Currently, two competing hypotheses exist: functional hypothesis, which proposes milk are transferred offspring and exert physiological regulatory functions, nutritional suggests these molecules do not reach systemic circulation recipient, but merely provide nutrition without conferring active signals offspring. The hypothesis based on indirect evidence requires further investigation....

10.1186/s12986-016-0101-2 article EN cc-by Nutrition & Metabolism 2016-06-21

During the COVID-19 pandemic, breastfeeding women have experienced restricted access to support, placing them at increased risk of mental health concerns and limited assistance. This study investigated effect pandemic on feeding choices maternal wellbeing amongst mothers living in Australian New Zealand. We conducted a cross-sectional online survey that examined methods, wellbeing, worries, challenges, positive experiences during pandemic. Most were exclusively (82%). Partial was associated...

10.3390/nu13061831 article EN Nutrients 2021-05-27

Human milk is a complex and variable ecosystem fundamental to the development of newborns. This study aimed investigate relationships between human oligosaccharides (HMO) bacterial profiles infant body composition. samples (n = 60) were collected at two months postpartum. Infant maternal composition was measured with bioimpedance spectroscopy. assessed using full-length 16S rRNA gene sequencing 19 HMOs quantitated high-performance liquid chromatography. Relative abundance taxa significantly...

10.3390/ijms23052865 article EN International Journal of Molecular Sciences 2022-03-05

Background: Whilst it is inconvenient and time-intensive, predominantly (PP) exclusively pumping (EP) mothers rely on breast expression to provide milk for their infants ensure continued supply, yet these populations are poorly understood. Methods: We assessed characterised Western Australian PP (n = 93) regarding 24 h production (MP) infant intake demographics, perinatal complications breastfeeding difficulties, the frequencies of which were compared with published general population...

10.3390/nu17020366 article EN Nutrients 2025-01-20
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