A5081292140- Immune Cell Function and Interaction
- Immune cells in cancer
- Galectins and Cancer Biology
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Cancer, Stress, Anesthesia, and Immune Response
- Infectious Encephalopathies and Encephalitis
- Macrophage Migration Inhibitory Factor
- Immunotherapy and Immune Responses
- Antimicrobial Peptides and Activities
- Liver Disease and Transplantation
- interferon and immune responses
- Alcoholism and Thiamine Deficiency
- Microbial Inactivation Methods
- Cancer Cells and Metastasis
- Cancer Immunotherapy and Biomarkers
- Renal Transplantation Outcomes and Treatments
- Vitamin C and Antioxidants Research
Zhejiang University
2022-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2025
National Clinical Research Center for Digestive Diseases
2023-2025
Blood Center of Zhejiang Province
2022-2023
First Affiliated Hospital Zhejiang University
2022-2023
State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
2023
Background & Aims: Regulatory T cells (Tregs) are an obstacle to PD-1 blockade-mediated antitumor efficacy. However, the behaviors of Tregs response anti-PD-1 in HCC and characteristics tissue adaptation from peripheral lymphoid tissues tumor still unclear. Approach Results: Here, we determine that monotherapy potentially augments accumulation CD4 + Tregs. Mechanistically, mediates proliferation rather than tumor. Increased burden replenishes intratumoral Tregs, raising ratio CD8 cells....
Abstract Tumor‐associated macrophages (TAMs) are commonly considered accomplices in tumorigenesis and tumor development. However, the precise mechanism by which cells prompt TAMs to aid evading immune surveillance remains be further investigated. Here, it is elucidated that tumor‐secreted galectin‐1 (Gal1) conferred immunosuppressive properties TAMs. Specifically, patient specimens a public database first used analyze clinical relevance of Gal1 hepatocellular carcinoma (HCC). Then,...
Background: The most effective treatment for end-stage liver diseases is transplantation, which impeded by the shortage of donor livers. Split transplantation (SLT) important addressing shortage. However, full-right full-left SLT two adult recipients globally rarely conducted. This study aimed to investigate clinical outcomes this technique. Methods: We retrospectively analyzed data 22 who underwent at Shulan (Hangzhou) Hospital between January, 2021 and September, 2022. graft-to-recipient...