- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Infective Endocarditis Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Blood Pressure and Hypertension Studies
- Congenital Heart Disease Studies
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Cardiovascular Issues in Pregnancy
- Cardiomyopathy and Myosin Studies
- Sodium Intake and Health
- Cardiac Fibrosis and Remodeling
- Obstructive Sleep Apnea Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiovascular Disease and Adiposity
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Streptococcal Infections and Treatments
- Vascular anomalies and interventions
- Acupuncture Treatment Research Studies
Dokkyo Medical University
2015-2024
Boehringer Ingelheim (South Korea)
2019
Abbott (Japan)
2019
Bayer (Germany)
2019
Medtronic (Ireland)
2019
Bayer (France)
2019
Mitsui Memorial Hospital
2019
Keio University
2015
Dokkyo University
1995
Background The management of mixed aortic valve disease (MAVD), defined as the concomitant presence stenosis (AS) and regurgitation, remains a clinical challenging. present study assessed impact transcatheter replacement (TAVR) on cardiac geometry prognosis in patients with MAVD. Methods Results A retrospective multicenter TAVR registry was conducted, including who underwent for severe symptomatic AS between January 2015 March 2019. Patients were subdivided into 2 groups according to...
Left atrial strain (LAS) measured by two-dimensional speckle tracking echocardiography (2DSTE) is considered to be a marker of LA structural remodeling, but it remains unsettled. We investigated the potential usefulness and clinical relevance LAS detect remodeling including fibrosis analyzing gene expression in cardiovascular surgery patients. Preoperative 2DSTE was performed 131 patients (92 with sinus rhythm [SR] paroxysmal AF [PAF], 39 fibrillation [AF]) undergoing surgery. Atrial samples...
Background Prognostic implications of transcatheter aortic valve implantation (TAVI) in low‐gradient (LG) stenosis (AS) remain controversial. The authors hypothesized that differences cardiac functional recovery may solve this ongoing controversy. aim was to evaluate clinical outcomes and the response left ventricular (LV) function following TAVI patients with LG AS. Methods Results This multicenter retrospective study included 1742 severe AS undergoing between January 2015 March 2019....
Abstract Aims The aim of this study was to identify phenotypes with potential prognostic significance in aortic stenosis (AS) patients after transcatheter valve replacement (TAVR) through a clustering approach. Methods and results This multi-centre retrospective included 1365 severe AS who underwent TAVR between January 2015 March 2019. Among demographics, laboratory, echocardiography parameters, 20 variables were selected dimension reduction used for unsupervised clustering. Phenotypes...
Abstract Despite the known association of cardiac rupture with acute myocardial infarction (AMI), it is still unclear whether clinical characteristics are associated risk in-hospital mortality in patients AMI complicated by rupture. The purpose this study was to investigate between time occurrence and after AMI. We conducted a retrospective analysis multicenter registry data from eight medical universities Eastern Japan. From 10,278 consecutive AMI, we included 183 who had examined incidence...
We herein report the case of a 72-year-old man with endocarditis aortic valve who underwent urgent replacement 36 hours after admission due to an aggravation regurgitation. Postoperative cultures blood and site vegetation identified Candida parapsilosis as pathogen. Antifungal therapy amphotericin B fluconazole was initiated surgical treatment. Thereafter, patient displayed favorable clinical course. involving native valves is extremely rare associated very high mortality rate. Prompt...
Objective Embolic events are frequent and life-threatening complications of infective endocarditis (IE). Recently, an embolic risk assessment at admission, based on the Risk (ER) French Calculator, was designed to predict development symptomatic emboli associated with IE. This study aimed validate ER Calculator for prediction in-hospital events, including events. Methods We retrospectively analyzed clinical features 52 consecutive patients left-sided IE identify possible predictors within 30...
A 58-year-old woman with a past medical history of carotid body tumor, resected 4 months prior to presentation, was admitted our hospital for treatment cardiac tumor that identified on post-operative echocardiography and chest computed tomography. The surgically removed pathologically as paraganglioma, similarly the tumor. Genetic analysis both tumors non-synonymous mutation in succinate dehydrogenase (SDH) gene D, Exon4, c.320T>C, p.Leu107Pro showing co-segregation paternal transmission...
We report the case of a 51-year-old female, in whom coronary artery disease such as occlusion septal perforators was manifested, on occasion hospitalization with congestive heart failure.The patient had history radiation therapy for mediastinal tumor 19 years previously.As she no conventional risk factors, cause is thought to have been related therapy.As survival rates cancer patients improve consequence therapeutic advances, we should be aware possibility very late complication therapy,...
Ischemic mitral regurgitation (MR) is a serious complication after myocardial infarction, and the incidence of heart failure (HF) increases as severity MR increases. However, little known about relationship between mild HF in patients with old infarction (OMI) normal ejection fraction (EF).We hypothesized that combination impaired distensibility left ventricle may increase risk diastolic OMI EF.The was retrospectively investigated 62 EF > 50% on echocardiography.Of patients, 47 (76%) did not...