A5102855071- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- COVID-19 and healthcare impacts
- Pancreatic and Hepatic Oncology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Multiple and Secondary Primary Cancers
- Trauma and Emergency Care Studies
- Cancer Treatment and Pharmacology
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic factors in colorectal cancer
- Peptidase Inhibition and Analysis
- Protease and Inhibitor Mechanisms
- Advances in Oncology and Radiotherapy
- Renal cell carcinoma treatment
- Pancreatitis Pathology and Treatment
- Radiation Dose and Imaging
- Statistical Methods in Clinical Trials
- Traditional Chinese Medicine Studies
- Anorectal Disease Treatments and Outcomes
- Surgical site infection prevention
- Signaling Pathways in Disease
- Sodium Intake and Health
- Cholangiocarcinoma and Gallbladder Cancer Studies
Sapporo Medical University
2023-2024
Institut de Virologie
2020-2022
University of Birmingham
2020
AstraZeneca (Brazil)
2020
Stryker (United Kingdom)
2020
Pfizer (United Kingdom)
2020
Merck (Germany)
2020
Tochigi Medical Center
2015-2019
National Hospital Organization
2015-2019
Yamagata Prefectural Central Hospital
2015
Abstract Background The aim of this study was to assess the impact inferior mesenteric artery (IMA) root nodal dissection before high ligation on survival in patients with sigmoid colon or rectal cancer. Methods Data 1188 consecutive who underwent resection for cancer, IMA, were identified from a prospective database (April 1965 December 1999). Survival involvement nodes along IMA proximal origin left colic (root nodes, station 253) through bifurcation superior (trunk 252) determined....
S-1 is a new oral formulation of 5-fluorouracil (5-FU) consisted 1M tegafur, 0.4M 5-chloro-2,4-dihydroxypyridine that inhibits degradation 5-FU, and potassium oxonate regulates the phosphorylation 5-FU in gastrointestinal tract, has shown excellent antitumor efficacy against various murine tumors rodents, compared to tegafur-based drug, UFT (1M tegafur plus 4M uracil), which used clinically Japan. To assess possibility using S-1, we investigated effect on human solid tumor xenografts athymic...
The clinical significance of plasma concentration matrix metalloproteinase 9 (MMP-9) was investigated in patients with gastric cancer.Plasma obtained from 138 healthy individuals and 70 who underwent gastrectomy for cancer at Aichi Cancer Centre between August 1994 July 1995. Plasma concentrations MMP-9 were measured using a one-step sandwich enzyme immunoassay employing monoclonal antibodies.Patients had higher than normal subjects. Postoperative lower preoperative levels. In addition to...
One thousand two hundred fifty-four cases (610 colonic and 644 rectal cancers resected during 2 years from 1984 followed up for more than 5 years) were entered 140 institutions in Japan analyzed by means of Cox's proportional hazards model. The pathologic variables the size depth invasion, Dukes' stage, venous lymphatic permeation, other clinical features, such as sex age patient location tumor. extent dissection, serum carcinoembryonic antigen (CEA) level, presence or absence adjuvant...
Patients with resectable (R) or borderline (BR) pancreatic ductal adenocarcinoma (PDAC) sometimes show unexpected liver, peritoneal, and para-aortic lymph node metastases intraoperatively. Despite radical pancreatectomy, a nonnegligible number of patients relapse within 6 months after surgery. The aim this study was to identify the preoperative predictors occult (OM), defined as intraoperative distant pancreatectomy.
Laparoscopic hepatectomy for colorectal liver metastases (CRLM) is performed worldwide. However, owing to a lack of palpatory information and difficulties associated with accurate intraoperative ultrasonographic diagnosis, the tumor may be exposed at hepatic transection margin. This study aimed investigate pathological significance near-infrared (NIR) fluorescence imaging indocyanine green (ICG)-guided laparoscopic determine its usefulness in securing resection margin CRLMs.
A coprological survey with detailed clinical observation of naturally occurring haemorrhagic enteritis (HE) cases was conducted to understand the pathophysiology HE by clarifying infection status Eimeria and enteropathogenic bacteria in cattle. Faecal samples from 55 26 clinically normal animals were collected, a quantitative examination potential performed. The number species oocysts per gram faeces (OPG) exceeded 10,000 69.1 cent maximum 1,452,500 OPG zuernii found be overwhelmingly...
Background Patients with resectable (R) or borderline (BR) pancreatic ductal adenocarcinoma (PDAC) sometimes show unexpected liver, peritoneal, and para-aortic lymph node metastases intraoperatively. Despite radical pancreatectomy, a nonnegligible number of patients relapse within 6 months after surgery. The aim this study was to identify the preoperative predictors occult (OM), defined as intraoperative distant pancreatectomy.Materials methods This included R BR PDAC who underwent...
大腸癌の同時性肝転移に対する本邦における治療の現況を明らかにするため,1997年の初回全国アンケート調査を引き継いで登録症例の追跡調査を行った.初回集積症例3,212例のなかで最終的に1,843症例が集積された.そのうちの解析適合症例446例を解析した.Hステージ別,転移個数別,転移腫瘍径別に治療方法別の有効性を検討したが,全てのステージで外科的切除が最も有効であった.特にH1症例,転移数3個以下,転移腫瘍径2.0cm以下の症例では,外科的切除を第一選択とすべきことが示唆された.またH2以上,転移個数4個以上,腫瘍径2.1cm以上の症例に関しては動注療法も有効であった.全身化学療法もH3や転移数5個以上のステージの進行した症例では有効性が認められた.
4093 Background: The results of phase I portion the treatment with oral S-1 (a new fluoropyrimidine) plus leucovorin (LV) in patients (pts) untreated metastatic colorectal cancer (mCRC) was reported at ESMO 2006. Dose limiting toxicities (DLTs) were grade 3 stomatitis/pharyngitis, nausea, diarrhea, ileus and exanthema. recommended doses (RDs) for this II determined to be 40 mg/m 2 LV 25 mg/body orally given twice daily on days 1 14 a 28-day cycle. PK profiles similar those monotherapy UFT...
Objectives: Among the preoperative and surgical findings in patients with thymoma, risk factors for pleural recurrence after complete resection were explored. Methods: Fifty-three Masaoka stage I to III thymoma who underwent 5 IVa disease comparison analysed. The longest diameter of tumour (LDT) contact length between contour lung (CLTL) measured on computed tomography (CT) scans. CLTL was evaluated at maximum section axial images (Fig. 1 (a)). A multivariate analysis including age, sex, WHO...