Shilpi Modi

ORCID: 0000-0002-0448-1185
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About
Contact & Profiles
Research Areas
  • Functional Brain Connectivity Studies
  • Advanced MRI Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Neural and Behavioral Psychology Studies
  • Neural dynamics and brain function
  • Neuroscience and Neuropharmacology Research
  • Epilepsy research and treatment
  • Fusion and Plasma Physics Studies
  • Pituitary Gland Disorders and Treatments
  • Thyroid Disorders and Treatments
  • EEG and Brain-Computer Interfaces
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Bone health and osteoporosis research
  • Olfactory and Sensory Function Studies
  • Cognitive Abilities and Testing
  • Acute Myeloid Leukemia Research
  • Atomic and Subatomic Physics Research
  • Tumors and Oncological Cases
  • Oral and Maxillofacial Pathology
  • Stress Responses and Cortisol
  • Psychosomatic Disorders and Their Treatments
  • Lymphoma Diagnosis and Treatment
  • Vestibular and auditory disorders
  • Meningioma and schwannoma management
  • Sarcoma Diagnosis and Treatment

Institute of Nuclear Medicine & Allied Sciences
2011-2024

Thomas Jefferson University
2020-2023

Artemis Hospitals
2018-2023

Jefferson Hospital for Neuroscience
2023

Institute of Liver and Biliary Sciences
2020

Defence Research and Development Organisation
2013-2015

Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences
2009-2012

Objective: Chronic alcoholism is associated with impaired cognitive abilities, a more severe deficit in visual than verbal functions. The processing deficits have classically been function of the cortex, located occipital lobe. present study sought to increase current understanding abilities alcohol-dependent subjects and their correlation metabolic aberrations lobe using vivo proton magnetic resonance spectroscopy (1H MRS). Method: To that end, 1H MRS was carried out primary cortex on 35...

10.15288/jsad.2014.75.817 article EN Journal of Studies on Alcohol and Drugs 2014-09-01

The present study aimed to investigate whether brain morphological differences exist between adult hypothyroid subjects and age-matched controls using voxel-based morphometry (VBM) with diffeomorphic anatomic registration via an exponentiated lie algebra algorithm (DARTEL) approach. High-resolution structural magnetic resonance images were taken in ten healthy subjects. analysis was conducted statistical parametric mapping. VBM revealed a reduction grey matter volume the left postcentral...

10.1111/jne.12001 article EN Journal of Neuroendocrinology 2012-10-11

Tuberculosis (TB) of the cervix is a rare disease. We describe two cases tuberculous cervicitis with variable clinical presentation. In one case, young woman presented primary infertility and secondary amenorrhoea. The other perimenopausal irregular vaginal bleeding postcoital blood-stained discharge. diagnosis was confirmed on histopathological examination endocervical curettings cervical biopsy. patients were given six months anti-tuberculous therapy responded well.

10.1258/td.2009.090423 article EN Tropical Doctor 2010-03-19

Hypothyroidism affects brain functioning as suggested by various neuroimaging studies. The primary focus of the present study was to examine whether hypothyroidism would impact connectivity among resting‐state networks ( RSN s) using functional magnetic resonance imaging (rsf MRI ). Twenty‐two patients with and 22 healthy controls were recruited scanned rsf . data analysed independent component analysis a dual regression approach that applied on five s identified fsl software...

10.1111/jne.12282 article EN Journal of Neuroendocrinology 2015-04-09

Abstract Subclinical hypothyroidism (SCH) is characterised by a mild elevation of thyroid‐stimulating hormone (range 5‐10 μIU mL ‐1 ) and normal free triiodothyronine thyroxine. Cognitive function impairment well known in thyroid disorders such as hyperthyroidism, although little about deficits brain functions SCH subjects. Also, whether hormone‐replacement treatment necessary or not subjects still debatable. To obtain an insight into the cognition subjects, intrinsic extrinsic functional...

10.1111/jne.12587 article EN Journal of Neuroendocrinology 2018-03-05

Despite the effectiveness of surgical interventions for treatment intractable focal temporal lobe epilepsy (TLE), substrates that support good outcomes are poorly understood. While algorithms have been developed prediction either seizure or cognitive/psychiatric alone, no study has reported on functional and structural architecture supports joint outcomes. We measured key aspects pre-surgical whole brain functional/structural network evaluated their ability to predict post-operative control...

10.1016/j.nicl.2023.103387 article EN cc-by-nc-nd NeuroImage Clinical 2023-01-01

<b><i>Introduction:</i></b> Hyperthyroidism, characterized by excessive thyroid hormone production, is a common endocrine disorder that affects various physiological processes, including brain function. Recent advancements in neuroimaging techniques have enabled researchers to investigate structural alterations the associated with hyperthyroidism. This study aimed examine regional cortical thickness and volume differences across between hyperthyroid patients control...

10.1159/000536027 article EN Neuroendocrinology 2024-01-01

Hyalinizing trabecular tumor (HTT) is an unusual and controversial lesion of the thyroid gland. Some have considered it a unique entity, some variant papillary carcinoma, still others nonspecific pattern that may be seen with variety lesions. The histological ultrastructural characteristics this neoplasm are well documented; however, its cytological diagnosis by fine needle aspiration cytology (FNAC) remains challenging. cytomorphological features entity overlap both medullary carcinoma to...

10.4103/0970-9371.70741 article EN cc-by-nc-sa Journal of Cytology 2010-01-01

Purpose: In the classical description of acute radiation syndrome, role central nervous system (CNS) is underestimated. It now well recognised that ionising radiation-induced oxidative stress may bring about functional changes in brain. this study, we prospectively evaluated metabolic brain after whole body irradiation mice using vivo proton (1H) nuclear magnetic resonance spectroscopy (MRS).Material and methods: Young adult were exposed to 8 Gy controls sham irradiated. 1H MRS from...

10.3109/09553002.2013.734944 article EN International Journal of Radiation Biology 2012-10-01

Primary melanotic meningeal neoplasms are extremely rare lesions and benign forms even rarer though with better prognosis than the malignant ones. We describe a 40-year-old male history of gradually progressive weakness both lower limbs normal bowel, bladder control, an intradural mass measuring 1.5×1.0 cm on radiologic investigations. The lesion was surgically excised. Histopathologic examination revealed heavily melanin-pigmented cells, nuclei reticulogranular chromatin small nucleoli,...

10.4103/1793-5482.92176 article EN Asian Journal of Neurosurgery 2011-12-01

Thyroid disease is known to affect brain metabolism and cognitive function, although the recovery of thyroid-induced functional changes after treatment remains unclear. We aimed investigate alteration in connectivity its correlation with neuropsychological variables hyperthyroid patients before anti-thyroid using a resting-state magnetic resonance imaging (rsfMRI) technique. This follow-up rsfMRI study previous work that showed impaired compared healthy controls. included data from 21 out an...

10.1111/jne.13075 article EN Journal of Neuroendocrinology 2021-12-05
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