A5034325179- Amphibian and Reptile Biology
- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Species Distribution and Climate Change
- Environmental DNA in Biodiversity Studies
- Gene expression and cancer classification
- Identification and Quantification in Food
- Genetics, Bioinformatics, and Biomedical Research
- Molecular Biology Techniques and Applications
- Bioinformatics and Genomic Networks
- Wildlife Ecology and Conservation
- Digital Imaging for Blood Diseases
- Scientific Computing and Data Management
- Animal Behavior and Reproduction
- Bat Biology and Ecology Studies
- Evolution and Genetic Dynamics
- Online Learning and Analytics
- Advanced Proteomics Techniques and Applications
- Genetic and phenotypic traits in livestock
- Fish Biology and Ecology Studies
- AI in cancer detection
- Spider Taxonomy and Behavior Studies
- Scarabaeidae Beetle Taxonomy and Biogeography
- Ovarian cancer diagnosis and treatment
- Fish Ecology and Management Studies
National Museum of Natural History
2018-2024
George Washington University
2019-2024
Smithsonian Institution
2018-2024
Deloitte (United States)
2021-2024
Center for Information Technology
2024
National Institutes of Health
2024
The University of Texas at Austin
2021
The University of Texas at Arlington
2015-2020
National Museum of Natural History
2019
University Surgical Associates
2016
Dusky Salamanders (genus
Abstract Background As genome sequencing becomes better integrated into scientific research, government policy, and personalized medicine, the primary challenge for researchers is shifting from generating raw data to analyzing these vast datasets. Although much work has been done reduce compute times using various configurations of traditional CPU computing infrastructures, Graphics Processing Units (GPUs) offer opportunities accelerate genomic workflows by orders magnitude. Here we...
The gekkonid genus Cyrtodactylus is the third most speciose vertebrate in world, containing well over 300 species that collectively range from South Asia to Melanesia across some of diverse landscapes and imperiled habitats on planet. A genus-wide phylogeny group has never been presented because researchers working different groups were using genetic markers construct phylogenies could not be integrated. We present here Maximum likelihood Bayesian inference mitochondrial mito-nuclear...
We present partial genome sequences of 50 salamander species (Urodela) from 10 genera and 4 families. These span nearly the entire range sizes in salamanders, ~14–130GB, latter which is among largest all animal genomes. Only three genomes were available to this point, Ambystomatidae (one species) Salamandridae (two two genera), we have added Amphiumidae species), Plethodontidae (45 6 Proteidae Sirenidae (three genera). ~140 million years evolutionary divergence, leaving only...
Abstract Effective conservation and management of pond‐breeding amphibians depends on the accurate estimation population structure, demographic parameters, influence landscape features breeding‐site connectivity. Population‐level studies typically sample larval life stages because they are easily captured can be sampled nondestructively. These often identify high levels relatedness between individuals from same pond, which exacerbated by sampling stage. Yet, effect these related genetic...
Abstract Significant advances have been made in species delimitation and numerous methods can test precisely defined models of speciation, though the synthesis phylogeography taxonomy is still sometimes incomplete. Emerging consensus treats distinct genealogical clusters genome-scale data as strong initial evidence speciation most cases, a hypothesis that must therefore be falsified under an explicit evolutionary model. We now hypotheses linking trait differentiation to specific mechanisms...
Abstract Aim This study seeks to understand the geological and climatological processes that have promoted biodiversity on Sunda Shelf in Southeast Asia. Using parachuting frog genus Rhacophorus , we estimate divergence times quantify respective contributions of between within‐island diversification species richness endemism. Location East Asia, Shelf. Methods We generated a concatenated mitochondrial nuclear DNA sequence alignment for 40 . estimated phylogenetic relationships times,...
The gekkonid genus Cyrtodactylus is the third most speciose vertebrate in world, containing well over 300 species that collectively range from South Asia to Melanesia across some of diverse landscapes and imperiled habitats on planet. A genus-wide phylogeny group has never been presented because researchers working different groups were using genetic markers construct phylogenies could not be integrated. We present here Maximum likelihood Bayesian inference mitochondrial mito-nuclear...
Abstract A period of isolation in allopatry typically precedes local adaptation and subsequent divergence among lineages. Alternatively, locally adapted phenotypes may arise persist the face gene flow, resulting strong correlations between ecologically‐relevant phenotypic variation corresponding environmental gradients. Quantifying genetic, ecological, such lineages can provide insights into abiotic biotic mechanisms that structure populations drive accumulation taxonomic diversity....
Abstract Multi-omics (genomics, transcriptomics, epigenomics, proteomics, metabolomics, etc.) research approaches are vital for understanding the hierarchical complexity of human biology and have proven to be extremely valuable in cancer precision medicine. Emerging scientific advances recent years made high-throughput genome-wide sequencing a central focus molecular by allowing collective analysis various kinds biological data from different types specimens single tissue or even at level...
We describe Cyrtodactylus psarops sp. nov. and C. semicinctus nov., two new species of bent-toed geckos from montane forests in the southern Bukit Barisan Range Sumatra, Indonesia. The are closely related to one another semenanjungensis, a lowland currently known only Peninsular Malaysia. Three characters immediately distinguish them most congeners Sunda Region: they lack transversely enlarged subcaudals, have precloacal depression, greatly scale positioned at apex continuous series femoral...
We redescribe Cyrtodactylus lateralis (Werner) on the basis of new specimens. is a prehensile-tailed species, known from scattered lowland to mid-elevation localities in northern Sumatra. The are more speciose and have wider distribution than previously thought. This group includes mainland SE Asian clade consisting C. elok, interdigitalis, brevipalmatus an insular containing durio, lateralis, nuaulu, serratus, spinosus, stresemanni. However, distinctive color pattern Wallacean Papuan...
Until recently many historical museum specimens were largely inaccessible to genomic inquiry, but high-throughput sequencing (HTS) approaches have allowed researchers successfully sequence DNA from dried and fluid-preserved specimens. In addition preserved specimens, museums contain large series of allozyme supernatant samples, the amenability these samples HTS has not yet been assessed. Here, we compared performance a target-capture approach using alternative sources 10 spring salamanders...
Abstract This manuscript describes the development of a resource module that is part learning platform named ‘NIGMS Sandbox for Cloud-based Learning’ https://github.com/NIGMS/NIGMS-Sandbox. The overall genesis described in editorial NIGMS at beginning this Supplement. delivers materials on protein quantification an interactive format uses appropriate cloud resources data access and analyses. Quantitative proteomics rapidly growing discipline due to cutting-edge technologies high resolution...
Abstract Allopatric divergence following the formation of geographical features has been implicated as a major driver evolutionary diversification. Widespread species complexes provide opportunities to examine allopatric across varying degrees isolation in both time and space. In North America, several may play such role diversification, including Mississippi River, Pecos Rocky Mountains, Cochise Filter Barrier, Gulf California Isthmus Tehuantepec. We used thousands nuclear single nucleotide...
ABSTRACT Microbial communities play key roles in ocean ecosystems through regulation of biogeochemical processes such as carbon and nutrient cycling, food web dynamics, gut microbiomes invertebrates, fish, reptiles, mammals. Assessments marine microbial diversity are therefore critical to understanding spatiotemporal variations community structure function ecosystems. With recent advances DNA shotgun sequencing for metagenome samples computational analysis, it is now possible access the...

 Historical student data can help elucidate the factors that promote success in mathematics courses. Herein we use both multiple regression and principal component analyses to explore ten years of historical from over 20,000 students an introductory college-level Algebra course urban American research university with a diverse population order understand relationship between performance previous courses, demographic background, time spent on coursework. We find indicators students’...
Abstract This manuscript describes the development of a resource module that is part learning platform named “NIGMS Sandbox for Cloud-based Learning” https://github.com/NIGMS/NIGMS-Sandbox. The overall genesis described in editorial NIGMS at beginning this Supplement. delivers materials on RNA sequencing (RNAseq) data analysis an interactive format uses appropriate cloud resources access and analyses. Biomedical research increasingly data-driven, dependent upon management methods facilitate...
We describe a new, narrowly endemic species of swamp-dwelling dusky salamander (Plethodontidae: Desmognathus pascagoula sp. nov.) from the Gulf Coastal Plain southeastern Mississippi and southwestern Alabama based on linear morphometrics, mitochondrial DNA, single nucleotide polymorphisms 881 loci produced using genotype-by-sequencing. Some populations new were historically referred to as D. auriculatus, polyphyletic assemblage at least three in Atlantic Texas North Carolina. Populations...