A5029466448- HIV, Drug Use, Sexual Risk
- Hepatitis C virus research
- Opioid Use Disorder Treatment
- HIV/AIDS Research and Interventions
- Substance Abuse Treatment and Outcomes
- COVID-19 epidemiological studies
- Data-Driven Disease Surveillance
- Hepatitis B Virus Studies
- Homelessness and Social Issues
- COVID-19 Digital Contact Tracing
- Mental Health Treatment and Access
- Health Policy Implementation Science
- Health Systems, Economic Evaluations, Quality of Life
- Forensic Toxicology and Drug Analysis
- Liver Disease Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- COVID-19 and Mental Health
- HIV/AIDS drug development and treatment
- Primary Care and Health Outcomes
- Child Nutrition and Water Access
- Cannabis and Cannabinoid Research
- Delphi Technique in Research
- Sleep and Work-Related Fatigue
- Alcohol Consumption and Health Effects
- Poverty, Education, and Child Welfare
Université de Montréal
2016-2025
Centre Hospitalier de l’Université de Montréal
2016-2025
Université de Sherbrooke
2019
Institut National de Santé Publique
2019
Abstract Background The COVID-19 pandemic had a disproportionate impact on the health and wellbeing of people who use drugs (PWUD) in Canada. However less is known about jurisdictional commonalities differences exposure impacts pandemic-related restrictions competing social risks among PWUD living large urban centres. Methods Between May 2020 March 2021, leveraging infrastructure from ongoing cohorts PWUD, we surveyed 1,025 participants Vancouver ( n = 640), Toronto 158), Montreal 227),...
People who use drugs (PWUD) are at high risk of experiencing indirect harms measures implemented to curb the spread COVID-19, given reliance on services and social networks. This study aimed document short-term changes in behaviours health-related indicators among PWUD Montreal, Canada following declaration a provincial health emergency Quebec.We administered structured rapid assessment questionnaire members an existing cohort individuals reporting past-year illicit drug recruited via...
Housing instability contributes to harm among people who inject drugs (PWID). We examined determinants of varying levels housing and explored gender differences in associated PWID. used baseline data from HEPCO, a community-based cohort PWID Montreal, Canada (2011-2022). (past 3 months) was categorised as stable, precarious (i.e., temporary accommodation) or unsheltered. Multinomial logistic regression assess relationships between sociodemographic factors, recent drug use, instability. A...
Opioid agonist treatment is considered important in preventing acquisition of hepatitis C virus (HCV) among people who inject drugs; however, the role dosage opioid unclear. We investigated joint association prescribed and patient-perceived adequacy with risk HCV infection drugs.We followed prospectively drugs at acquiring (who were RNA negative HCV-antibody or positive) Montréal, Canada (2004-2017). At 6-month, then 3-month intervals, participants tested for antibodies RNA, completed an...
The COVID-19 pandemic has spurred an unprecedented demand for interventions that can reduce disease spread without excessively restricting daily activity, given negative impacts on mental health and economic outcomes. Digital contact tracing (DCT) apps have emerged as a component of the epidemic management toolkit. Existing DCT typically recommend quarantine to all digitally-recorded contacts test-confirmed cases. Over-reliance testing may, however, impede effectiveness such apps, since by...
Barriers to HCV treatment initiation persisted after the introduction of direct-acting antivirals (DAAs) in Canada among people who inject drugs (PWID); whether DAA universal coverage lifted these barriers remain unknown. We assessed evolution and associated factors PWID Montreal, Canada, comparing eras IFN-based regimens (2011-2013), restricted access (2014-02/2018), (03/2018-03/2020).We included chronically HCV-infected participants followed a community-based cohort between 2011 03/2020...
Amphetamine injection is expanding in North America and has been associated with male homosexuality among people who inject drugs (PWID). Applying subcultural evolution theory, we examined overall gender-stratified trends amphetamine assessed sexual orientation as a gender-specific predictor of initiation PWID Montreal, Canada.Data were from HEPCO, an open prospective cohort PWID. Gender self-identified at enrolment. Interviewer-administered questionnaires three-monthly (HCV RNA-negative...
Keywords: hepatitis C elimination; COVID-19; SARS-CoV-2; priority populations; people who use drugs Author Affiliation
Hepatitis C virus (HCV) acquisition remains high in key risk environments including injection drug use and sex between men. However, few studies examine the independent contribution of sexual behaviour to HCV among people who inject drugs (PWID). We estimated incidence examined as a time-varying predictor prospective cohort study PWID Montreal (2004-2017). Initially, HCV-negative participants completed behavioural questionnaires antibody testing (6 months until 2011, 3 thereafter). A...
Disbursement of income assistance has been temporally associated with intensified drug use and related harms (coined the 'cheque effect'). However, relationships to injection (IDU) remain understudied. We examined short-term effects' factors among people who inject drugs (PWID).Cross-sectional analysis nested within a cohort study.Montreal, Quebec, Canada.PWID receiving assistance, no employment income. A total 613 PWID (median age 41, 83% male) contributed 3269 observations from 2011...
Cluster randomised trials (CRTs) are a key instrument to evaluate public health interventions, particularly in low- and middle-income countries (LMICs). Fidelity assessment examines study processes gauge whether an intervention was delivered as initially planned. Evaluation of implementation fidelity (IF) is required establish the measured effects trial due itself may be important for CRTs complex interventions. Current CRT reporting guidelines offer no guidance on IF assessment. We will...