A5081060373- Antifungal resistance and susceptibility
- Parasitic Diseases Research and Treatment
- Fungal Infections and Studies
- Air Quality and Health Impacts
- Immune cells in cancer
- Occupational and environmental lung diseases
- Antibiotic Use and Resistance
- Antimicrobial Peptides and Activities
Baylor College of Medicine
2022
The University of Texas MD Anderson Cancer Center
2019
St. John's School
2018
Chronic exposure to airborne carbon black ultrafine (nCB) particles generated from incomplete combustion of organic matter drives IL-17A-dependent emphysema. However, whether and how they alter the immune responses lung cancer remains unknown. Here, we show that nCB increased PD-L1
Background: The incidence of fungal infections has increased significantly, contributing to morbidity and mortality. This is caused by an alarming increase in with multi-drug resistant bacteria leading overuse broad-spectrum antimicrobials, which lead overgrowth Candida, thus enhancing its opportunity cause disease. Candida are major human pathogens that both mucosal deep tissue infections. Objective: aim our study was identify the distribution species among clinical isolates their...
Candida auris is an emerging, often MDR, yeast pathogen. Efficient animal models are needed to study its pathogenicity and treatment. Therefore, we developed a C. fruit fly infection model.TollI-RXA/Tollr632 female flies were infected with 10 different strains from the CDC Antimicrobial Resistance bank panel. We used three clinical albicans as controls. For drug protection assays, survival was assessed along measurement of fungal burden (cfu/g tissue) histopathology in auris-infected fed...
Candida auris is an emerging multi-drug-resistant human pathogen. Experimental data on the pathogenicity of C. scarce, especially regarding its virulence compared with albicans. Additionally, studies drug efficacy against rely conventional animal models that are laborious and low throughput; alternative, less cumbersome desirable. To end, we developed a fly infection model. We injected 2-week-old TollI-RXA/Tollr632 female flies needle dipped in solutions (108 yeast cells/mL) dorsal side...