Joshua Herb

ORCID: 0000-0002-0503-3739
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About
Contact & Profiles
Research Areas
  • Global Cancer Incidence and Screening
  • Economic and Financial Impacts of Cancer
  • Cutaneous Melanoma Detection and Management
  • Global Health Workforce Issues
  • Pancreatic and Hepatic Oncology Research
  • Cardiac tumors and thrombi
  • Healthcare Policy and Management
  • Venous Thromboembolism Diagnosis and Management
  • Colorectal Cancer Screening and Detection
  • Vascular Tumors and Angiosarcomas
  • Advances in Oncology and Radiotherapy
  • Health Systems, Economic Evaluations, Quality of Life
  • Cancer Genomics and Diagnostics
  • Parkinson's Disease Mechanisms and Treatments
  • Lung Cancer Treatments and Mutations
  • Neurological disorders and treatments
  • Nonmelanoma Skin Cancer Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Sarcoma Diagnosis and Treatment
  • Appendicitis Diagnosis and Management
  • Lung Cancer Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Opioid Use Disorder Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • CAR-T cell therapy research

The University of Texas MD Anderson Cancer Center
2023-2025

Icahn School of Medicine at Mount Sinai
2024

University of North Carolina at Chapel Hill
2018-2023

Duke Medical Center
2022

Sylvester Comprehensive Cancer Center
2022

UNC Lineberger Comprehensive Cancer Center
2022

University of Miami
2022

Medical College of Wisconsin
2022

University of North Carolina Health Care
2022

Communities In Schools of Orange County
2020

679 Background: Patients racialized as Black experience higher incidence and mortality from pancreatic cancer (PC). The aim of this study was to examine differences in receipt guideline concordant care (GCC) among older adults with PC Black, White, or Hispanic ethnicity. Methods: 65 years incident ethnicity were identified the SEER-Medicare database 2004-2019. primary outcome GCC (stage I/II: surgery+chemotherapy+/-radiation; stage III: chemotherapy+/-surgery+/-radiation; IV:...

10.1200/jco.2025.43.4_suppl.679 article EN Journal of Clinical Oncology 2025-01-27

Parkinson's Disease patients with predominant gait dysfunction appear to have reduced cortical thickness compared other motor phenotypes. The extent which advancing age or disease duration impact the pattern of these distinctions is unclear.We examine if PD signs postural instability and are distinguished by distinct patterns cerebral atrophy, how differences influenced duration.The Unified Rating Score (UPDRS) was administered 196 (age = 61.4±8.9yrs) in Off On dopamine state. All completed...

10.3233/jpd-150753 article EN Journal of Parkinson s Disease 2016-05-26

We evaluated temporal trends in rural-urban disparities of the surgeon supply among surgeons commonly treating patients with cancer.We performed a retrospective observational study county-level workforce changes from 2004 to 2017 using Area Health Resource File. calculated physician density (providers/100,000 population) for each specialty by rural and urban counties 2003 Rural-Urban Commuting Codes (RUCC), percent disparity density. Secondary analyses these Census region. Additionally, Gini...

10.1111/jrh.12658 article EN The Journal of Rural Health 2022-03-14

Advancing age and disease duration both contribute to cortical thinning in Parkinson's (PD), but the pathological interactions between them are poorly described. This study aims distinguish patterns of decline determined by advancing PD. A convenience cohort 177 consecutive PD patients, identified at Vanderbilt University Movement Disorders Clinic as part a clinical evaluation for Deep Brain Stimulation (age: M= 62.0, SD 9.3), completed standardized assessment, along with structural brain...

10.14336/ad.2015.1110 article EN cc-by Aging and Disease 2016-01-01

Abstract Purpose Major cancer surgeries have regionalized to fewer and higher‐volume hospitals, with the goal of improving quality surgical care. However, regionalization may negative effects on geographic access We hypothesize that lung patients been traveling further for surgery over time as has occurred, this increased travel primarily impacted rural patients. Methods A North Carolina all‐payer state discharge database was used capture discharges from 2005 2015 undergoing resection....

10.1111/jrh.12440 article EN The Journal of Rural Health 2020-05-01

Abstract Background and Objectives Synovial, clear cell, angiosarcoma, rhabdomyosarcoma, epithelioid (SCARE) soft tissue sarcoma are at risk for nodal involvement, although the positivity rates impact on prognostication in clinically node negative patients not well described. Methods Patients with extremity SCARE without clinical involvement undergoing surgical resection National Cancer Database (2004–2017) were included. Logistic regression was used to evaluate likelihood of surgery...

10.1002/jso.26465 article EN Journal of Surgical Oncology 2021-03-22

Abstract Background Guidelines recommend extended venous thromboembolism (VTE) prophylaxis for high‐risk populations undergoing major abdominal cancer operations. Few studies have evaluated VTE in the Medicare population who are at higher risk due to age. Methods We performed a retrospective study using 20% random sample of claims, 2012–2017. Patients ≥65 years with an resection were included. Primary outcome was proportion patients receiving new prescriptions discharge. Secondary outcomes...

10.1002/jso.27473 article EN Journal of Surgical Oncology 2023-10-06

In patients with chronic rhinosinusitis nasal polyps, primary human sinonasal epithelial cell (HSNEC) 1α-hydroxylase levels are reduced, as is their ability to metabolize 25-hydroxycholecalciferol [25(OH)D<sub>3</sub>] its active metabolite, 1α,25-dihydroxyvitamin D<sub>3</sub> [1,25(OH)<sub>2</sub>D<sub>3</sub>]. this study, we sought identify the factor responsible for regulation of HSNEC metabolism 25(OH)D<sub>3</sub>, focusing on C3 and C3a. Multiple inhaled irritants trigger release...

10.18043/ncm.83.4.294 article EN North Carolina Medical Journal 2022-07-01

Abstract Background Anti-integrin αvβ6 autoantibodies (anti-αvβ6) are a novel biomarker of ulcerative colitis (UC) that precede disease diagnosis by up to 10 years. Given integrin is also expressed on the biliary epithelium and primary sclerosing cholangitis (PSC) co-occurs with inflammatory bowel (IBD) in 90% patients, we aimed determine prevalence anti-αvβ6 patients PSC understand impact course. Methods Three cohorts pre-liver transplant controls (IBD non-IBD) were recruited from New York,...

10.1093/ecco-jcc/jjad212.0013 article EN Journal of Crohn s and Colitis 2024-01-01
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