- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Multiple Myeloma Research and Treatments
- RNA modifications and cancer
- Hematopoietic Stem Cell Transplantation
- Circular RNAs in diseases
- Genomics and Chromatin Dynamics
- Hemoglobinopathies and Related Disorders
- Blood Coagulation and Thrombosis Mechanisms
- HIV-related health complications and treatments
- Immunodeficiency and Autoimmune Disorders
- Genomic variations and chromosomal abnormalities
- Dendrimers and Hyperbranched Polymers
- Maternal and Neonatal Healthcare
- Environmental and biological studies
- Chromosomal and Genetic Variations
- Eosinophilic Disorders and Syndromes
- Lymphoma Diagnosis and Treatment
- Iron Metabolism and Disorders
- SARS-CoV-2 and COVID-19 Research
- Genomics and Rare Diseases
Hospital Israelita Albert Einstein
2012-2023
RESUMO Objetivo: Estimar os intervalos de referência (IR) parâmetros hemograma completo na população adulta brasileira. Métodos: Estudo transversal, com dados da Pesquisa Nacional Saúde (PNS), entre 2014–2015. A amostra final constitui-se 2.803 adultos. Para estabelecer IR, aplicou-se critérios exclusão, removeram-se outliers e foram feitos particionamentos por sexo, idade raça/cor pele. Adotou-se o método não paramétrico. As diferenças avaliadas pelos testes Mann Withney Kruskal Wallis...
The aim of this study was to investigate the prevalence human immunodeficiency virus (HIV) infection among transgender women and travestis analyze factors associated with HIV in Brazil.
Despite advances in understanding of carcinogenesis and treatment acute myeloid leukemia, this neoplasm still has a lethality at least 30%. The search for biomarkers that can predict the response to early stages disease is necessary. In recent years, new form cellular communication between tumor non-neoplastic cells been discovered: exchange information through extracellular vesicles. These are small vesicles released by membrane-coated carry proteins, lipids, messenger RNAs, microRNA DNA,...
Objetivo: A utilização de anticorpos monoclonais conjugados para a quantificação linfócitos T na rotina diagnóstica laboratorial é grande importância, pois minimiza erros pipetagem, diminui o custo e otimiza tempo, proporcionando melhoria qualidade produtividade do processo. Este trabalho teve objetivo comparar desempenho dois painéis em um teste CD3, CD4 CD8. Método: Neste estudo, utilizamos total 10 amostras sangue periférico. Para cada 100ul As foram marcadas com seguinte painel 1...
Herein, we aimed to follow up on the cellular and humoral immune responses of a group individuals who initially received CoronaVac vaccine, followed by booster with Pfizer vaccine.Blood samples were collected: before 30 days after first dose; 30, 90, 180 second dose, also 20 vaccine.Whilst positivity gamma interferon-type response increased neutralizing IgG antibody levels only raised drop in these 90 days. The vaccine elicited robust response. A higher number double-negative senescent T...
Abstract Introduction Minimal residual disease (MRD) is a cornerstone for stratification of upfront B‐lymphoblastic leukemia (B‐ALL) treatment protocols to decrease relapse risk. Although its detection by flow cytometry (FC) and real‐time quantitative polymerase has clinical usefulness, evidence suggests that methods with increased sensitivity could lead improved outcomes. The aim this study was develop an amplicon‐based assay followed high‐throughput sequencing the immunoglobulin heavy...