A5015697885- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Neuroscience and Neuropharmacology Research
- Polydiacetylene-based materials and applications
- Tryptophan and brain disorders
- Immune cells in cancer
- Immunotherapy and Immune Responses
- Photoacoustic and Ultrasonic Imaging
- Photodynamic Therapy Research Studies
- Olfactory and Sensory Function Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Pain Mechanisms and Treatments
- Cancer Immunotherapy and Biomarkers
- Neurotransmitter Receptor Influence on Behavior
- Air Quality and Health Impacts
Hainan University
2020-2023
Hainan Medical University
2023
State Key Laboratory of Digital Medical Engineering
2023
Abstract Synergistic photothermal immunotherapy has captured great attention owing to the mutually strengthening therapeutic outcomes towards both original tumors and abscopal tumors. Herein, a versatile theranostic agent displaying aggregation‐induced emission, namely TPA‐BT‐DPTQ, was designed prepared based on benzo[ c ]thiophene unit as building block; it can be used for simultaneous fluorescence imaging (FLI) in second near‐infrared (NIR‐II) window, photoacoustic (PAI), (PTI), thermal...
Abstract To address urgent tasks in the treatment of advanced deep‐seated tumors, a 980 nm absorbing agent with aggregation‐induced emission tendency, namely TPE‐BT‐BBTD, which simultaneously possesses longest absorption wavelength among all reported AIE molecules is developed. The functionality deep near‐infrared‐II fluorescence imaging (NIR‐II FLI) and outstanding photothermal performance well‐tailored for pancreatic cancer treatment. With covalent attachment programmed death‐ligand 1...
Background Ocular myasthenia gravis (OMG) is a neuromuscular disorder primarily affecting the extraocular muscles, leading to ptosis and diplopia. Effective patient education crucial for disease management; however, in China, limited health care resources often restrict patients’ access personalized medical guidance. Large language models (LLMs) have emerged as potential tools bridge this gap by providing instant, AI-driven information. However, their accuracy readability educating patients...
Abstract Synergistic photothermal immunotherapy has captured great attention owing to the mutually strengthening therapeutic outcomes towards both original tumors and abscopal tumors. Herein, a versatile theranostic agent displaying aggregation‐induced emission, namely TPA‐BT‐DPTQ, was designed prepared based on benzo[ c ]thiophene unit as building block; it can be used for simultaneous fluorescence imaging (FLI) in second near‐infrared (NIR‐II) window, photoacoustic (PAI), (PTI), thermal...
<sec> <title>BACKGROUND</title> Ocular myasthenia gravis (OMG) is a neuromuscular disorder primarily affecting the extraocular muscles, leading to ptosis and diplopia. Effective patient education crucial for disease management; however, in China, limited health care resources often restrict patients’ access personalized medical guidance. Large language models (LLMs) have emerged as potential tools bridge this gap by providing instant, AI-driven information. However, their accuracy...
Alcohol has complex effects on cerebrovascular health. Monitoring the pathology of alcohol induced changes in vivo is essential for understanding mechanism and developing potential treatment strategies. Here, photoacoustic imaging was employed to examine mice under at different doses. By analyzing association structure, hemodynamics, neuronal function corresponding behavior, we found that affected brain behavior a dose-dependent manner. Low dose increased blood volume activated neurons,...
Morphine addiction causes major medical and social problems worldwide. Chronic morphine exposure results in the development of behavioral sensitization, accompanied by disruption brain homeostasis. As a key reward region, nucleus accumbens (NAc) plays central role mechanisms. Furthermore, neurons NAc are impaired chronic abuse, but contribution to is poorly understood. Here we indicated that morphine-induced an abnormal neuronal activation NAc. Critically, found remarkable increase...